Results 311 to 320 of about 23,125,138 (369)
Identification of potential inhibitors of interleukin-2-inducible T-cell kinase: insights from docking, molecular dynamics, MMPBSA and free energy landscape studies. [PDF]
Amino AcidsAhmed S +8 more
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Interleukin-2 receptor signaling acts as a checkpoint that influences the distribution of regulatory T cell subsets. [PDF]
iScienceShouse AN, Villarino AV, Malek TR.
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Serum Soluble Interleukin-2 Receptor as a Potential Marker for Assessing Disease Activity in the TAFRO Subtype of Idiopathic Multicentric Castleman Disease. [PDF]
Intern MedOzaki T +8 more
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Interleukin-2–based therapies in cancer
Science Translational Medicine, 2022Molecular insights into the mechanism of beneficial and adverse effects of interleukin-2 (IL-2) have resulted in the development of improved IL-2 formulations with IL-2 receptor bias and tissue-targeting properties.
M. E. Raeber, Dilara Şahin, O. Boyman
semanticscholar +1 more source
Acta Clinica Belgica, 1987
SummaryDiscovered in 1976, the lymphokine interleukin-2, intensively studied during the last years, plays a major role in the regulation of the immune function. The authors reviewing its principal properties, anticipate forthcoming prospects of considerable implications in therapy.Acta Clin. Bclg. 42, 4: 255–68.
M, Hiden, P, Nève
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SummaryDiscovered in 1976, the lymphokine interleukin-2, intensively studied during the last years, plays a major role in the regulation of the immune function. The authors reviewing its principal properties, anticipate forthcoming prospects of considerable implications in therapy.Acta Clin. Bclg. 42, 4: 255–68.
M, Hiden, P, Nève
openaire +2 more sources
Leukemia Research, 1990
Interleukin 2 receptors (IL-2-R) are composed of (at least) two chains: the alpha chain (or p55 or Tac) and the beta chain (or p70 or p75). The association of both chains constitutes high affinity IL2-R complexes (Kd congruent to 10-100 pM), whereas the alpha-chain or the beta chain alone bind IL-2 with low (Kd congruent to 5-50 nM) and intermediate ...
M, Allouche +5 more
openaire +2 more sources
Interleukin 2 receptors (IL-2-R) are composed of (at least) two chains: the alpha chain (or p55 or Tac) and the beta chain (or p70 or p75). The association of both chains constitutes high affinity IL2-R complexes (Kd congruent to 10-100 pM), whereas the alpha-chain or the beta chain alone bind IL-2 with low (Kd congruent to 5-50 nM) and intermediate ...
M, Allouche +5 more
openaire +2 more sources