Results 41 to 50 of about 22,558,942 (346)
Interleukin‐1α, interleukin‐2, and soluble interleukin‐2 receptors in polymyositis [PDF]
Arthritis & Rheumatism, 1990 AbstractCell‐mediated immunity has been implicated in the pathogenesis of polymyositis (PM). We conducted a prospective study in which serum levels of soluble interleukin‐2 receptors (IL‐2R), IL‐1α, and IL‐2 were correlated with creatine kinase (CK) levels and clinical disease activity.
Bruce A. Baethge, Robert E. Wolf
openaire +3 more sources
Рациональная фармакотерапия в кардиологии, 2017 Aim. To study possible variants of changes in structural and functional parameters of central hemodynamics in liver cirrhosis classes A, B, C (Child– Pugh) to improve the early diagnostics of extrahepatic complications.Material and methods. Parameters of
V. E Kulikov +5 more
doaj +1 more source
THE INVESTIGATION OF SOME CYTOKINES ROLE IN THE DEVELOPMENT OF ALOPECIA AREATA
Вісник проблем біології і медицини, 2020 The immune response plays a leading role in the pathogenesis of alopecia areata which develops by Тh1-type with the formation of a large number of proinflammatory cytokines: IL-1, IL-2, IL-6, IL-8, IFN-γ and TNF-α. The anti-inflammatory cytokines disrupt
Aljabali M. A., Kuts L. V.
doaj +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Expression of chicken interleukin-2 gene in Pichia methanolica
浙江大学学报. 农业与生命科学版, 2003 Chicken interleukin-2 (chIL-2) is an important cytokine discovered recently. To explore a new approach to the expression of chIL-2 gene in methyltrophic yeast-Pichia methanolica (P.
ZHOU Ji-yong +4 more
doaj +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
مجلة كلية الطب, 2017 Background: Osteoporosis is a frequent disease that is manifested by reduced in mineral density and raised in fracture risk. Recent studies have indicated that osteoporosis is caused by composite connections among local and systemic regulators of bone ...
Hind Sh. Ahmed
doaj +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
FEBS Letters, EarlyView.Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Interleukin-2 and regulatory T cells in graft-versus-host disease.
New England Journal of Medicine, 2011 BACKGROUND Dysfunction of regulatory T (Treg) cells has been detected in diverse inflammatory disorders, including chronic graft-versus-host disease (GVHD). Interleukin-2 is critical for Treg cell growth, survival, and activity.
J. Koreth +17 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu +17 more
wiley +1 more source