Results 161 to 170 of about 3,093,388 (334)

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim, Ning Guo, Zong Yao Tan, Xing Gao, Pouria Fattahi, Haijiao Liu, Jeehan Chang, Mousa Younesi, Selice Jung, Yewhan Chung, Minkyung Song, Michelle Jung, Dan Dongeun Huh   +12 more
wiley   +1 more source

Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus [PDF]

, 2007
Amr H. Sawalha, Kenneth M. Kaufman, Jennifer A. Kelly, Adam J. Adler, Teresa Aberle, J Kilpatrick, Edward K. Wakeland, Q-Z Li, Amy E. Wandstrat, David R. Karp, Judith A. James, Joan T. Merrill, Peter E. Lipsky, John B. Harley   +13 more
openalex   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Usefulness of Uric Acid to Predict Changes in C-Reactive Protein and Interleukin-6 in 3-Year Period in Italians Aged 21 to 98 Years [PDF]

, 2007
Carmelinda Ruggiero, Antonio Cherubini, Edgar R. Miller, Marcello Maggio, Samer S. Najjar, Fulvio Lauretani, Stefania Bandinelli, Umberto Senin, Luigi Ferrucci   +8 more
openalex   +1 more source

Regulation of SOX11 expression through CCND1 and STAT3 in mantle cell lymphoma [PDF]

, 2019
The neural transcription factor SOX11 is usually highly expressed in typical mantle cell lymphoma (MCL), but it is absent in the more indolent form of MCL.
Budde, Elizabeth, Chan, Wing C., Chen, Robert W., Kwak, Larry W., Mei, Matthew, Mohanty, Atish, Müschen, Markus, Ngo, Vu N., Nguyen, Thang V., Pham, Lan V., Phan, An, Popplewell, Leslie, Rosen, Steven T., Sandoval, Natalie, Weisenburger, Dennis D.   +14 more
core   +1 more source

Salt‐Compact Albumin as a New Pure Protein‐based Biomaterials: From Design to In Vivo Studies

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
A new class of materials built entirely of native albumin protein is designed using a simple protocol based on salt‐assisted compaction, breaking with current crosslinking strategies. This green process leads, surprisingly, to water‐insoluble handable materials with high preservation of their native protein structures and Young's modulus close to that ...
Eya Aloui, Jordan Beurton, Claire Medemblik, Ludivine Hugoni, Igor Clarot, Ariane Boudier, Youri Arntz, Marcella De Giorgi, Jérôme Combet, Guillaume Fleith, Eric Mathieu, Naji Kharouf, Leyla Kocgozlu, Benoît Heinrich, Damien Favier, Michael Brender, Fouzia Boulmedais, Pierre Schaaf, Benoît Frisch, Philippe Lavalle   +19 more
wiley   +1 more source

Activation of Natural killer cells with interleukin 21 in the treatment of preclinical Neuroblastoma model

Fiyz̤, 2021
Background: Neuroblastoma (NB) is one of the most prevalent children's neoplasm and some of which still do not respond to common treatments and is an ideal candidate for NK cell immune therapy.
Alireza Shoae Hassani, Mahdi Shadnoush, Hadi Kazemi, Nasim Vosughi, Rashin Mohseni, Iman Seihoon, Javad Verdi   +6 more
doaj  

The Existence of Multiple Conformers of Interleukin-21 Directs Engineering of a Superpotent Analogue [PDF]

, 2007
Kent Bondensgaard, Jens Breinholt, Dennis Madsen, Diana Højmark Omkvist, Lishan Kang, Anne Worsaae, Peter B. Becker, Christine Bruun Schiødt, Siv A. Hjorth   +8 more
openalex   +1 more source

Gasotransmitters in Modern Medicine: Promises and Challenges in the Use of Porous Crystalline Carriers

Advanced Healthcare Materials, EarlyView.
This perspective provides an overview of the growing interest in utilizing various gasotransmitters—small gaseous signaling molecules namely nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S)—for several therapeutic applications, with emphasis on the potential use of porous materials as carriers to provide safe and controlled local ...
Rosana V. Pinto, Moisés L. Pinto, Christian Serre   +2 more
wiley   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source