Results 81 to 90 of about 73,008,320 (286)

IL-22 regulates genes involved in intestinal immune defence responses.

, 2019
WT organoids were treated with IL-22 (2 ng/ml) for 3 hours. RNA was isolated for RNAseq analysis. (A) Volcano plot showing fold change (log2) in gene expression of WT organoids treated with IL-22 (2 ng/ml) for 3 hours compared to untreated WT organoids ...
Yu Chen (29959), Ignacio Moraga (8044517), Maud Vandereyken (4506520), Mahima Swamy (8044523), Ian P. Newton (8044514), Inke S. Näthke (8044520)   +5 more
core   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

The Role of IL-22 in Viral Infections: Paradigms and Paradoxes

Frontiers in Immunology, 2016
Interleukin-22 (IL-22) is a member of the IL-10 family of cytokines. Hematopoietic cells express IL-22, and this cytokine signals through the heterodimeric IL-22R expressed by non-hematopoietic cells.
Silvia eGimeno Brias, Gabrielle eStack, Maria A Stacey, Alec J Redwood, Ian R Humphreys   +4 more
doaj   +1 more source

Interleukin 22 serum levels are associated with radiographic progression in rheumatoid arthritis [PDF]

, 2011
To study the role of interleukin 22 (IL-22) in rheumatoid arthritis (RA)
Dechant, Claudia, Schramm, Markus A., Grunke, Mathias, Baeuerle, Michael, Schulze-Koops, Hendrik, Leipe, Jan, Reindl, Christiane S., Nigg, Axel P., Vielhauer, Volker, Skapenko, Alla, Witt, Matthias N., C. Dechant, M. Grunke, J. Leipe, M. N. Witt, A. Skapenko, C. S. Reindl, V. Vielhauer, M. A. Schramm, H. Schulze-Koops, M. Baeuerle, A. P. Nigg   +21 more
core   +1 more source

Serum levels of interleukin-17, -18, -22, and -25 in patients with bullous pemphigoid before and after treatment

Frontiers in Medicine
ObjectiveThis study aimed to explore the relationship between serum levels of interleukin-17 (IL-17), interleukin-18 (IL-18), interleukin-22 (IL-22), interleukin-25 (IL-25), anti-BP180 antibodies, anti-BP230 antibodies, and immunoglobulin E (IgE) and the
Xinyi Hong, Xinyi Hong, Xinyi Hong, Xinyi Hong, Xiuqin Wang, Xiuqin Wang, Xiuqin Wang, Xiuqin Wang, Yin Cheng, Yin Cheng, Yin Cheng, Yin Cheng, Hanqing Song, Hanqing Song, Hanqing Song, Hanqing Song, Congcong Xu, Congcong Xu, Congcong Xu, Congcong Xu, Peiguang Wang, Peiguang Wang, Peiguang Wang, Peiguang Wang   +23 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

High fat diet induces formation of spontaneous liposarcoma in mouse adipose tissue with overexpression of interleukin 22.

PLoS ONE, 2011
Interleukin 22 (IL-22) is a T-cell secreted cytokine that modulates inflammatory response in nonhematopoietic tissues such as epithelium and liver. The function of IL-22 in adipose tissue is currently unknown.
Zheng Wang, Ling Yang, Yuhui Jiang, Zhi-Qiang Ling, Zhigang Li, Yuan Cheng, Heng Huang, Lingdi Wang, Yi Pan, Zhenzhen Wang, Xiaoqiang Yan, Yan Chen   +11 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source