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More than a decoy receptor? Interleukin 22 Binding Protein (IL-22BP) in bacterial pneumonia

The Journal of Immunology, 2018
Abstract IL-22 is secreted by lymphoid cells such as Th17 cells and ILC3s. The IL-22 receptor is composed of IL-22Ra1 and IL-10Rbeta. In the lung, the IL-22R localizes in the upper airway epithelial cells. We previously reported that IL-22 contains pneumococcal lung infection due to hepatic activation of C3 and improved cellular ...
Giraldina Trevejo-Nunez   +3 more
openaire   +1 more source

Plasma interleukin-22 and its cellular receptor (IL-22RA1) expression in chronic lymphocytic leukemia

The Egyptian Journal of Haematology, 2013
Background Chronic lymphocytic leukemia (CLL) is an environment-dependent hematologic malignancy where interactions with accessory cells through cytokines and their receptors seem to confer a survival advantage, thus contributing to disease progression.
NihalM. Heiba, ShereenA. Elshazly
openaire   +1 more source

Functional characterisation of the Interleukin-22 receptor

2003
Interleukin-22 is a cytokine originally identified as an IL-9-induced gene that belongs to a family of IL-10-related cytokines, composed of IL-10, IL-22, IL-19, IL-20, mda-7/IL-24 and AK155/IL-26. So far, the main biological activity of IL-22 is the induction of acute phase reactants expression in liver and pancreas.
Renauld, Jean-Christophe, Lejeune, Diane
openaire   +1 more source

Interleukin 22 receptor abundance and signaling is regulated by the ubiquitin proteasome and glycogen synthase kinase 3β. (INM2P.422)

The Journal of Immunology, 2014
Abstract Signaling through the interleukin (IL)-22 cytokine axis provides essential immune protection in the setting of extracellular infection at mucosal and other epithelial surfaces. Molecular regulation of IL-22 receptor (IL-22R) protein has not been characterized.
Nathaniel Weathington   +5 more
openaire   +1 more source

Interleukin-22 receptor 1 upregulation and activation in hypoxic endothelial cells improves perfusion recovery in experimental peripheral arterial disease

Biochemical and Biophysical Research Communications, 2018
Inflammation induced by muscle ischemia is involved in tissue repair and perfusion recovery in peripheral arterial disease (PAD) patients. Interleukin (IL)-22 is an inflammatory cytokine discovered in recent years and shows versatile functions; however, its role in PAD remains unknown.
Hongyao, Hu   +4 more
openaire   +2 more sources

Interleukin 22 receptor alpha1 is expressed by both the luminal and glandular epithelia of the day 34 pregnant mare uterus (P6319)

The Journal of Immunology, 2013
Abstract Invasive trophoblast cells of the equine chorionic girdle (CG) migrate through maternal endometrium to form endometrial cups, dense accumulations of cells that produce equine chorionic gonadotropin from days 40 to 120 of pregnancy.
Margaret Brosnahan   +3 more
openaire   +1 more source

Ectopic expression of Interleukin-22 receptors (IL-22R1) on lymphocytes induces multi-organ inflammation and premature death (35.12)

The Journal of Immunology, 2010
Abstract IL-22 signals through a heterodimeric receptor composed of IL-22R1 and IL-10R2. The IL-22R1 chain of this heterodimeric receptor is not expressed on leukocytes, but aberrant expression of this receptor has been found on ALK+ anaplastic large cell lymphoma.
Ram Savan   +8 more
openaire   +1 more source

Critical Care Management of Chimeric Antigen Receptor T-Cell Therapy Recipients

Ca-A Cancer Journal for Clinicians, 2022
Sandrine Valadè   +2 more
exaly  

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