Results 41 to 50 of about 62,501,450 (280)

Interleukin 27 and viral hepatitis [PDF]

Hepatology, 2009
The last few years have seen major advances in the treatment of hepatitis C. Yet despite the use of ribarvirin and peg-IFN-alpha therapy more than half of treated patients are unable to develop a sustained viral clearance (SVC), essential for the avoidance of the long term complications of chronic viral infection (1).
Arian, Laurence, Paul, Klennerman
openaire   +2 more sources

Correlation between serum AQP-4 antibody, inflammatory cytokines and recurrence of neuromyelitis optica in patients with chronic insomnia

Zhongguo linchuang yanjiu, 2022
Objective To investigate the levels of serum aquaporin 4(AQP-4) antibodies and cytoinflammatory factors in patients with neuromyelitis optica(NMO) complicated with chronic insomnia and their correlation with the recurrence of NMO. Methods A total of 103
WANG Feng, HU Xiao-ping, TIAN Ru-ping
doaj   +1 more source

The Role of Interleukin-27 In Patients With Allergic Rhinitis: A Single Center Study [PDF]

Zagazig University Medical Journal
Background: A newly discovered cytokine called interleukin-27 (IL-27) has both pro- and anti-inflammatory effects in various illnesses. But up until now, its role in the pathophysiology of allergic rhinitis (AR) was unclear.
Dina Shabana, Ayman Allam, Dina Abd-El hamed, Mohamed Abdelhady, Fedaa Nabil   +4 more
doaj   +1 more source

Keratoacanthoma Accompanied by Multiple Lung Squamous Cell Carcinomas Developing in a Renal Transplant Recipient

Case Reports in Dermatology, 2014
Keratoacanthoma (KA) is a benign keratinocytic neoplasm that spontaneously regresses after 3-6 months and shares features with well-differentiated squamous cell carcinoma (SCC). An increased incidence of both KA and non-melanoma skin tumor, including SCC,
Sadanori Furudate, Taku Fujimura, Aya Kakizaki, Yumi Kambayashi, Akira Hashimoto, Setsuya Aiba   +5 more
doaj   +1 more source

Ligand-Mediated Targeting of Cytokine Interleukin-27 Enhances Its Bioactivity In Vivo

Molecular Therapy: Methods & Clinical Development, 2020
We have examined the role of a novel targeted cytokine, interleukin-27 (IL-27), modified at the C terminus with a dual targeting and therapeutic heptapeptide, in treating prostate cancer.
Marxa L. Figueiredo, Manoel Figueiredo Neto, Janelle Wes Salameh, Richard E. Decker, Rachel Letteri, Delphine Chan-Seng, Todd Emrick   +6 more
doaj   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem, Herrmann, Eva, Oliver Waidmann, Kronenberger, Bernd, Friederike Brunner, Rudloff, Ina, Bernd Kronenberger, Waidmann, Oliver, Albrecht Piiper, Pfeilschifter, Josef (Prof. Dr.), Piiper, Albrecht, Heiko Mühl, Filmann, Natalie, Ina Rudloff, Malte Bachmann, Eva Herrmann, Josef Pfeilschifter, Lisa Kapper, Bachmann, Malte, Brunner, Friederike, Kapper, Lisa, Mühl, Heiko, Natalie Filmann, Zeuzem, Stefan, Kronenberger Bernd, Brunner Friederike, Filmann Natalie, Kapper Lisa, Herrmann Eva, Zeuzem Stefan, Mühl Heiko, Rudloff Ina, Piiper Albrecht, Waidmann Oliver, Bachmann Malte, Pfeilschifter Josef   +35 more
core   +2 more sources

Association Between IL-27 and IL-6 Serum Levels and IgA Nephropathy Alterations

Kidney and Dialysis
Background: IgA nephropathy (IgAN) is the most common primary glomerulonephritis, characterized by immune dysregulation and progressive renal injury. Among immunoregulatory mediators, interleukin-6 (IL-6) and interleukin-27 (IL-27) have been implicated ...
Julian Ananiev, Elina Aleksandrova, Nedelina Terzieva, Iskui Erkanyan, Eduard Tilkiyan, Milena Nikolova-Vlahova   +5 more
doaj   +1 more source

High interleukin 27 production is associated with early clinical stage and localized disease in patients with melanoma [PDF]

Journal of Medical Biochemistry, 2016
Background: The immune response in patients with me I anoma is an important focus of research due to the tumor's resistance and immunotherapy possibilities. IL-27 is one of the cytokines with antitumor properties. The role of IL-27 in the pathogenesis of
Pantić-Biševac Jelena, Stanojević Ivan, Mijušković Željko, Banović Tatjana, Đukić Mirjana, Vojvodić Danilo   +5 more
doaj  

The antitumor potential of Interleukin-27 in prostate cancer

Oncotarget, 2013
Prostate cancer (PCa) is of increasing significance worldwide as a consequence of the population ageing. Fragile elderly patients may particularly benefit from noninvasive and well tolerable immunotherapeutic approaches. Preclinical studies have revealed that the immune-regulatory cytokine IL-27 may exert anti-tumor activities in a variety of tumor ...
DI CARLO, EMMA, SORRENTINO, CARLO, Zorzoli A, Di Meo S, Tupone MG, Ognio E, MINCIONE, Gabriella, Airoldi I.   +7 more
openaire   +5 more sources

Interleukin-27 augments the inhibitory effects of sorafenib on bladder cancer cells

, 2017
Both sorafenib and interleukin-27 (IL-27) are antineoplastic drugs. This study aimed to investigate the synergistic effect of these two drugs on bladder cancer cells.
J.Y. Cao (6512813), X. Han (3042561), X.Q. Yu (6512822), H.S. Li (6512819), H.S. Yin (6512816)   +4 more
core   +1 more source