Results 21 to 30 of about 62,501,450 (280)
Interleukin 33, soluble suppression of tumorigenicity 2, interleukin 27, and galectin 3 as predictors for outcome in patients admitted to intensive care units [PDF]
Open Medicine, 2023 Intensive care units (ICUs) are expert hospital areas that provide treatment and 24 h care for people who are very sick. Sepsis represents a serious, severe condition and it can lead to septic shock and multiple organ dysfunction syndromes and is one of ...Eric Stevan, Zaric Radica Zivkovic, Jevdjic Jasna, Drakulic Svetlana Miletic, Stanojevic Ivan, Vojvodic Danilo, Arsenijevic Petar, Stojanovic Bojan, Jakovljevic Stefan, Markovic Nenad, Zaric Milan, Canovic Petar, Nesic Jelena, Zornic Nenad +13 moredoaj +2 more sourcesAutophagy, Interleukin 27, mycobacterium, tuberculosis
, 2018 Interleukin-27 (IL-27), a key immunoregulatory cytokine plays an important role in host responseto mycobacterial infection as neutralization of IL-27 augments intracellular killing of mycobacteria.Autophagy has a pivotal role in host immunity and is regulated by various cytokines. Here, we report thatIL-27 inhibits IFN- and starvation induced autophagy gaurav sharma (5598827)openaire +2 more sourcesDiagnostic Accuracy of Interleukin 27 for the Diagnosis of Pleural Tuberculosis. [PDF]
TanaffosPleural tuberculosis (TB) is one of the most common forms of extra-pulmonary TB. Since diagnosis is challenging through microbiological tests, discovering new diagnostic techniques with higher accuracy could help us improve early detection and lead to better outcomes.Marjani, Majid, Aghebatkheyri, Amir Reza, Dalil Roofchayee, Neda, Eslaminejad, Alireza, Azimi, Mojdeh, Eskandari, Alireza, Abedin, Atefeh, Sadr, Makan, Poorhosseini, Seyed Mohammad, Rezaei, Mitra, Mortaz, Esmaeil +10 moreopenaire +3 more sourcesT cell intrinsic STAT1 signaling prevents aberrant Th1 responses during acute toxoplasmosis
Frontiers in Immunology, 2023 Infection-induced T cell responses must be properly tempered and terminated to prevent immuno-pathology. Using transgenic mice, we demonstrate that T cell intrinsic STAT1 signaling is required to curb inflammation during acute infection with Toxoplasma ...Aaron B. Schultz, Aaron B. Schultz, David G. Kugler, Luis Nivelo, Luis Nivelo, Nicolas Vitari, Nicolas Vitari, Nicolas Vitari, Laura P. Doyle, Laura P. Doyle, Svetlana Ristin, Svetlana Ristin, Lothar Hennighausen, John J. O’Shea, Dragana Jankovic, Alejandro V. Villarino, Alejandro V. Villarino +16 moredoaj +1 more sourceInterleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies [PDF]
, 2012 BACKGROUND: Persistent inflammation has been proposed to contribute to various stages in the pathogenesis of cardiovascular disease. Interleukin-6 receptor (IL6R) signalling propagates downstream inflammation cascades.Thomas, GN, Willeit, P, Trip, MD, Willeit, J, Nelson, Christopher P, Samani, NJ, Danesh, J, Psaty, Bruce M., Assimes, Themistocles L., Stringham, Heather M, Kastelein, JJP, Adamovic, Svetlana, Franks, Paul W., Trip, Mieke D, Harris, Tamara B, Meade, TW, Thomas, Graham; id_orcid, Tivesten, A, de Bakker, PIW, Tybjærg-Hansen, Anne, Boehnke, M, de Bakker, Paul IW, Wilson, Anthony G, Trip, Mieke D., Witteman, Jacqueline C. M., Freitag, DF, Sarwar, Nadeem, Gao, P, Gallacher, John Edward, Ljunggren, Osten, Qi, Lu, Hall, Alistair S., Samani, Nilesh J., Karlsson, Magnus, Hofman, Bert, Goodall, AH, Watkins, H, Arbor, Ann, Davey Smith, George, Chambers, John C, Shaffer, Jonathan A, Butterworth, Adam S., Tracy, Russell P, O'Donnell, CJ, Gorman, Donal N., Psaty, Bruce M, Panagiotakos, DB, Wilde, Arthur AM, Best, LG, Di Angelantonio, Emanuele, Sundstrom, J, Butterworth, AS, Emerging Risk Factors Collaboration (Döring, A. ; Meisinger, C.), Cambien, Francois, Gregson, J, Gorman, Donal N, Best, Lyle G., Manson, JE, Rimm, Eric B, Wennberg, P, de Bakker, Paul I. W., Melzer, D, Qi, L, Gillum, Richard F, Kleber, ME, Gallacher, John, Kastelein, John JP, Chasman, DI, Cambien, F, Ridker, Paul M, Salomaa, Veikko, Hall, AS, Benjamin, Emelia J., Chasman, Daniel I, Salonen, JT, Kaptoge, S, Salonen, Jukka T., O'Donnell, Christopher J., Ingelsson, Erik, Benjamin, Emelia J, Freitag, Daniel F, Rader, Daniel J., Tracy, Russell P., Salonen, Jukka T, Saleheen, D, ?, ?, Salomaa, V, Clarke, Robert, Kleber, Marcus E., Chambers, JC, Witteman, Jacqueline C M, Braund, Peter S., Manson, JoAnn E., Boehnke, Michael, Ouwehand, Willem H, Rendon, A, Wilson, Anthony G., Harari, Olivier, Hopewell, Jemma C., Wilson, AG, Tracy, RP, Karlsson, M, Cantin, B, Reilly, Muredach P., Ohlsson, C, Melzer, David, IL6R Genetics Consortium Emerging Risk Factors Collaboration, Meade, Tom W, Benjamin, EJ, Stringham, Heather M., Freitag, Daniel F., Cantin, Bernard, Gregson, John, Chasman, Daniel I., Butterworth, Adam S, Reich, David, Braund, PS, Schunkert, H, Di Angelantonio, E, Ouwehand, WH, Harris, Tamara B., Thomas, G. Neil, Allin, Kristine H., Nelson, CP, Allin, Kristine Højgaard, Best, Lyle G, de Faire, Ulf, Davey-Smith, George, Kooner, Jaspal S, Gudnason, Vilmundur, Rimm, Eric B., Shaffer, Jonathan A., Sundstrom, Johan, Jansson, JO, Erdmann, Jeanette, Steri, M, Kauhanen, J, Holm, H, Samani, Nilesh J, Nordestgaard, BG, Mellstrom, Dan, Rader, Daniel J, Kaptoge, Stephen, Goodall, Alison H., Meade, Tom W., Clarke, R, Shaffer, JA, Ben-Shlomo, Yoav, Wilson, James F, Witteman, JCM, Ridker, PM, Davey-Smith, G, Tivesten, Asa, Koenig, W, Franks, Paul W.,, O'Donnell, Christopher J, Allin, Kristine H, van der Schoot, CE, Reilly, MP, Asselbergs, FW, Nelson, Christopher P., Hung, J, Danesh, John, Witteman, Jacqueline CM, Gudnason, V, Adamovic, S, Holm, Hilma, Kleber, Marcus E, Cushman, M, Ljunggren, Östen,, Erdmann, J, Koenig, Wolfgang, Rimm, EB, Hung, Joseph, Asselbergs, Folkert W., van der Schoot, C. Ellen, Wassertheil-Smoller, S, Kooner, Jaspal S., Panagiotakos, Demosthenes B, Franks, Paul, Willeit, Peter, Nordestgaard, Børge G, Kooner, JS, Chambers, John C., Tybjaerg-Hansen, Anne, Nordestgaard, Borge G., Tybjaerg-Hansen, A, Kauhanen, Jussi, Wilde, Arthur A. M., Gillum, RF, Watkins, Hugh, Mellstrom, D, Thomas, G Neil, Sarwar, N, de Faire, U, Wilde, AAM, Psaty, BM, Ben-Shlomo, Y, Panagiotakos, Demosthenes B., Ljunggren, O, Harris, TB, Sundström, Johan,, Reilly, Muredach P, Wilde, Arthur A M, Asselbergs, Folkert W, Woodward, Mark, Stringham, HM, Harari, O, Saleheen, Danish, Schunkert, Heribert, Hall, Alistair S, Cushman, Mary, Gorman, DN, Gillum, Richard F., Hopewell, Jemma C, Wilson, JF, IL6R Genetics Consortium, Rader, DJ, Wilson, James F., Kastelein, John J. P., Woodward, M, Hopewell, JC, Hofman, Albert, Rendon, Augusto, Wennberg, Patrik, Jansson, John-Olov, Wilhelmsen, L, Reich, D, Manson, JoAnn E, Onat, A, Amouyel, Philippe, Hamsten, A, Ingelsson, E, Franks, Paul W, Willeit, Johann, Onat, Altan, Wilhelmsen, Lars, Assimes, Themistocles L, Gallacher, J, Wassertheil-Smoller, Sylvia, van der Schoot, C Ellen, Assimes, TL, Goodall, Alison H, Franks, PW, Amouyel, P, Steri, Maristella, Ohlsson, Claes, Braund, Peter S, Allin, KH, Hamsten, Anders, Ridker, Paul M., Ouwehand, Willem H., Gao, Pei, Uitterlinden AG, Stark K, Asselbergs FW, Gregson J, Baumert J, Böhm BO, Kleber ME, Butterworth AS, de Jong JS, Yarnell JW, Danesh J. Collaborators Assimes TL, Wennberg P, Rimm EB, Preuss M, Qi L, Ripatti S, Stefanadis C, Smith AV, Ben Shlomo Y, Rasheed A, Ridker PM, Goodall AH, Karlsson, Magnus,, Kuusisto J, Tikkanen E, Rose LM, Perola M, Dupuis J, Armitage J, Mukamal KJ, Wilson JF, Nordestgaard BG, Hu FB, Jula A, Cheng KK, Reich D, Thorsteinsdóttir U, Thompson PL, Quertermous T, Nieminen MS, Illig T, Lind L, Gallacher J, Tivesten Å, Basu S, Mellström D, Stringham HM, Winkelmann BR, Silveira A, Tivesten, Åsa,, O'Donnell CJ, Whincup PH, Arveiler D, Morris RW, Guralnik JM, Sinisalo J, Maiwald S, Scharnagl H, Jansson JH, van der Schouw YT, Jansson JO, Tuomainen TP, Chasman DI, Freitag DF, Hengstenberg C, Tracy RP, Peden JF, Dehghan A, Fontes JD, Lam TH, Gigante B, Sivapalaratnam S, Hall AS, Harris TB, Lund University., Laakso M, Wilde AA, Nahrstaedt J, Deloukas P, Dagenais GR, Sarwar N, Qu L, Hofman A, Benjamin EJ, Loley C, Kastelein JJ, Rumley A, Heckbert SR, Koenig IR, Beilby JP, Clarke R, Bezzina CR, Amouyel P, Howard BV, Kaptoge S, de Bakker PI, Willenborg C, Shungin D, Schunkert H, Wassertheil Smoller S, Gillum RF, Barroso I, Mellström, Dan,, Gao P, Di Angelantonio E, Tuomilehto J, Cantin B, Shaffer JA, Jansson, John-Olov,, Ingelsson E, Männistö S, Knowles JW, Wilhelmsen L, Singleton AB, Koenig W, Chambers JC, Das D, Davidson KW, Psaty BM, Willeit J, Willeit P, Hlatky MA, Hankinson SE, Schreiber S, Wiggins KL, Panagiotakos DB, Dekker LR, Salonen JT, Manson JE, Thomas GN, Watkins H, Lokki ML, Pai J, Ljunggren Ö, McQuillan BM, Buring J., Adamovic, Svetlana,, Go AS, Gorman DN, Boehnke M, Bis JC, Witteman JC, Adamovic S, Sheikh N, Havulinna AS, Thorleifsson G, Reilly MP, Folsom AR, Sanna S, Fraser R, Meisinger C, Karlsson MK, Kauhanen J, Li M, van Duijn CM, Cambien F, Samani NJ, Davey Smith G, Assimes TL, de Faire U, Meade TW, van der Schoot CE, Verschuren WM, Ohlsson, Claes,, Motazacker M, Allin KH, Sabater Lleal M, Smith NL, Danesh J, Jackson A, Kurl S, Tanck M, Shea SJ, Yin X, Kooner JS, Collins R, Zhang W, Steri M, Thorand B, Saleheen D, CUCCA, Francesco, Gudnason V, Harari O, Melzer D, Onat A, Best LG, Tybjærg Hansen A, Nelson CP, Onland Moret NC, Franks PW, Rosengren A, Karlsson M, Erdmann J, Basart H, Wannamethee SG, Salomaa V, Ouwehand WH, Trip MD, Woodward M, Rendon A, Parish S, Balmforth AJ, Braund PS, Stefansson K, Abecasis GR, Ohlsson C, Sundström J, Hveem K, Hólm H, Ferrucci L, Syvänen AC, Hallmans G, Hopewell JC, Lowe G, Pitsavos C, Kiechl S, Farrall M, Thorgeirsson G, Hamsten A, Rader DJ, Boer JM, Franks, Paul,, Jiang CC, Chrysohoou C, Hung J, Bandinelli S, Schlessinger D, März W, Uda M, Cushman M, Wilson AG, Thompson JR, Qasim A, Sarwar, N;Butterworth, AS;Freitag, DF;Gregson, J;Willeit, P;Gorman, DN;Gao, P;Saleheen, D;Rendon, A;Nelson, CP;Braund, PS;Hall, AS;Chasman, DI;Tybjærg-Hansen, A;Chambers, JC;Benjamin, EJ;Franks, PW;Clarke, R;Wilde, AA;Trip, MD;Steri, M;Witteman, JC;Qi, L;van der Schoot, CE;de Faire, U;Erdmann, J;Stringham, HM;Koenig, W;Rader, DJ;Melzer, D;Reich, D;Psaty, BM;Kleber, ME;Panagiotakos, DB;Willeit, J;Wennberg, P;Woodward, M;Adamovic, S;Rimm, EB;Meade, TW;Gillum, RF;Shaffer, JA;Hofman, A;Onat, A;Sundström, J;Wassertheil-Smoller, S;Mellström, D;Gallacher, J;Cushman, M;Tracy, RP;Kauhanen, J;Karlsson, M;Salonen, JT;Wilhelmsen, L;Amouyel, P;Cantin, B;Best, LG;Ben-Shlomo, Y;Manson, JE;Davey-Smith, G;de Bakker, PI;O'Donnell, CJ;Wilson, JF;Wilson, AG;Assimes, TL;Jansson, JO;Ohlsson, C;Tivesten, Å;Ljunggren, Ö;Reilly, MP;Hamsten, A;Ingelsson, E;Cambien, F;Hung, J;Thomas, GN;Boehnke, M;Schunkert, H;Asselbergs, FW;Kastelein, JJ;Gudnason, V;Salomaa, V;Harris, TB;Kooner, JS;Allin, KH;Nordestgaard, BG;Hopewell, JC;Goodall, AH;R, Campbell H, Wild S, Kooner AS +489 morecore +2 more sourcesPotent Antitumor Activity of Interleukin-27 [PDF]
Cancer Research, 2004 AbstractAlthough much promising data that interleukin (IL)-12 could be a powerful therapeutic agent against cancer were reported in animal models, its excessive toxicity has become a problem for its clinical application. IL-27 is a novel IL-12 family member that plays a role in the early regulation of T helper cell 1 initiation, including induction of ...Hisada, Masayuki, Kamiya, Sadahiro, Fujita, Koji, Belladonna, Maria Laura, Aoki, Tatuya, Koyanagi, Yasuhisa, Mizuguchi, Junichiro, Yoshimoto, Takayuki +7 moreopenaire +3 more sourcesDecreased expression of interleukin‐27 in immune thrombocytopenia [PDF]
British Journal of Haematology, 2011 SummaryPrimary immune thrombocytopenia (ITP) is an immune‐mediated disorder in which disturbed cytokine profiles have been found. Interleukin‐27 (IL27) has been shown to bear both proinflammatory and anti‐inflammtory effects. In the present study, plasma levels of IL27, interferon gamma (IFNG), IL4, and IL17A were determined by enzyme‐linked ...Xin-guang, Liu, Juan, Ren, Yuan, Yu, Lin, Sun, Yan, Shi, Ping, Qin, Lei, Yang, Shi-hui, Ma, Xiao-yuan, Dong, Dao-xin, Ma, Xun, Qu, Cheng-shan, Guo, Chun-yan, Chen, Ming, Hou, Jun, Peng +14 moreopenaire +2 more sources
