Results 11 to 20 of about 1,334,419 (369)

Effects of Interleukin-2 (IL-2) and Interleukin-6 (IL-6) in Recurrent Spontaneous Abortion (RSA).

Iraqi Journal of Pharmaceutical Sciences, 2017
Recurrent Spontaneous Abortion (RSA) is the most painful experience for couples expecting a child. This study aimed to determine the relevance of IL-2 and IL-6 in recurrent spontaneous abortion (RSA).  Serum samples were collected from 90 women attend Al
Dhamraa w. Ahmed
doaj   +5 more sources

Clearance rates and systemic effects of intravenously administered interleukin 2 (IL-2) containing preparations in human subjects. [PDF]

British Journal of Cancer, 1983
The present study was designed to examine the feasibility of in vivo administration of interleukin 2 (IL-2) to induce cytotoxic cell activity against tumours in human subjects.
C. Bindon, M. Czerniecki, P. Ruell, A. Edwards, W. McCarthy, R. Harris, P. Hersey   +6 more
semanticscholar   +2 more sources

Constitutive Binding of the Transcription Factor Interleukin-2 (IL-2) Enhancer Binding Factor to the IL-2 Promoter* [PDF]

Journal of Biological Chemistry, 1997
A positive regulatory element in the interleukin-2 (IL-2) promoter, designated the antigen receptor response element-2, is essential for the induction of IL-2 gene expression upon the binding of an inducible multiprotein complex of proteins known as ...
A. Nirula, D. J. Moore, R. Gaynor
semanticscholar   +2 more sources

Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes. [PDF]

Blood, 1996
J. Drach, A. Gsur, G. Hamilton, Shourong Zhao, J. Angerler, Michael Fiegl, N. Zojer, M. Raderer, I. Haberl, M. Andreeff, H. Huber   +10 more
semanticscholar   +2 more sources

Diminished Proliferation of Human Immunodeficiency Virus-Specific CD4+ T Cells Is Associated with Diminished Interleukin-2 (IL-2) Production and Is Recovered by Exogenous IL-2

Journal of Virology, 2003
Christiana Iyasere, J. Tilton, Alison Johnson, Souheil-Antoine Younes, B. Yassine-Diab, R. Sékaly, W. Kwok, S. Migueles, Alisha C. Laborico, W. Shupert, C. Hallahan, R. Davey, M. Dybul, S. Vogel, J. Metcalf, M. Connors   +15 more
semanticscholar   +2 more sources

Localization of Salmonella and albumin-IL-2 to the tumor microenvironment augments anticancer T cell immunity

Journal of Biomedical Science, 2022
Background For centuries, microbial-based agents have been investigated as a therapeutic modality for the treatment of cancer. In theory, these methods would be cheap to produce, broadly applicable in a wide array of cancer types, and could synergize ...
Yu-Jui Kung, Brandon Lam, Ssu-Hsueh Tseng, Alana MacDonald, Hsin-Fang Tu, Suyang Wang, John Lin, Ya Chea Tsai, T. C. Wu, Chien-Fu Hung   +9 more
doaj   +1 more source

Blood levels of pro-inflammatory and anti-inflammatory cytokines during an oral glucose tolerance test in patients with symptoms suggesting reactive hypoglycemia [PDF]

Brazilian Journal of Medical and Biological Research, 2016
We evaluated the impact of postprandial glycemia on blood levels of pro-inflammatory and anti-inflammatory cytokines during an oral glucose tolerance test in non-diabetic patients with symptoms suggesting reactive hypoglycemia.
W. Eik Filho, S.S. Marcon, T. Krupek, I.T.S. Previdelli, O.C.N. Pereira, M.A.R.C.P. Silva, R.B. Bazotte   +6 more
doaj   +3 more sources

Reigniting hope in cancer treatment: the promise and pitfalls of IL-2 and IL-2R targeting strategies

Molecular Cancer, 2023
Interleukin-2 (IL-2) and its receptor (IL-2R) are essential in orchestrating immune responses. Their function and expression in the tumor microenvironment make them attractive targets for immunotherapy, leading to the development of IL-2/IL-2R-targeted ...
Shan Muhammad, Tao Fan, Yang Hai, Yibo Gao, Jie He   +4 more
doaj   +1 more source

Increased Protein Stability and Interleukin-2 Production of a LATG131D Variant With Possible Implications for T Cell Anergy

Frontiers in Cell and Developmental Biology, 2020
The adaptor LAT plays a crucial role in the transduction of signals coming from the TCR/CD3 complex. Phosphorylation of some of its tyrosines generates recruitment sites for other cytosolic signaling molecules.
Mikel M. Arbulo-Echevarria, Inmaculada Vico-Barranco, Isaac Narbona-Sánchez, Francisco García-Cózar, Francisco García-Cózar, Arkadiusz Miazek, Enrique Aguado, Enrique Aguado   +7 more
doaj   +1 more source

A Comprehensive Review of Low-Dose Interleukin-2 (IL-2) Therapy for Systemic Lupus Erythematosus: Mechanisms, Efficacy, and Clinical Applications. [PDF]

Cureus
Farooq A, Trehan S, Singh G, Arora N, Mehta T, Jain P, Bector G, Jain A, Arora RS, Puri P.   +9 more
europepmc   +3 more sources