Results 111 to 120 of about 2,248,771 (288)

The immunoprotective activity of interleukin-33 in mouse model of cecal ligation and puncture-induced sepsis

open access: yes, 2016
Lymphocyte apoptosis plays a pivotal role in sepsis-induced immunosuppression and is the primary cause of high mortality rates. Interleukin-33 is a member of the interleukin-1 family that is involved in the polarization of T cells toward a T helper 2 ...
An, You-Zhong   +3 more
core   +1 more source

Real‐world effectiveness and safety of secukinumab in giant cell arteritis: an Italian multicentre cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective The objective of this study was to evaluate the real‐world effectiveness and safety of secukinumab in giant cell arteritis (GCA) patients. Methods This multicentre retrospective study included patients with GCA who received secukinumab at 14 Italian centres with at least 6 months of follow‐up.
Luca Iorio   +29 more
wiley   +1 more source

Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus

open access: yes, 2019
[[abstract]]BackgroundHypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals.
Huang, HT;Tsai, SF;Wu, HT;Huang, HY;Hsieh, HH;Kuo, YM;Chen, PS;Yang, CS;Tzeng, SF
core   +1 more source

Genetically Programmed Shape‐Morphing of Engineered Living Materials

open access: yesAdvanced Functional Materials, EarlyView.
Here, bacterial and mammalian engineered living materials (ELMs) are presented, in which living cells direct genetically programmed and enzymatically mediated shape‐morphing. The resulting deformation and shape‐recovery can be actuated in a genetically controlled manner by an ELM incorporating out‐of‐equilibrium counteracting biochemical reactions with
Jan Becker   +7 more
wiley   +1 more source

Correlation of interleukin-33 with Th cytokines and clinical severity of dry eye disease

open access: yesIndian Journal of Ophthalmology, 2018
Purpose: The purpose of this study is to determine the tear and serum protein levels of interleukin-33 (IL-33) and its correlation with Th cytokines and disease severity in dry eye (DE) syndrome.
Guoping Luo   +5 more
doaj   +1 more source

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study [PDF]

open access: yes, 2012
Background: Interleukin-22 (IL-22), recently identified as a crucial parameter of pathology in experimental liver damage, may determine survival in clinical end-stage liver disease.
Stefan Zeuzem   +23 more
core   +2 more sources

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

interleukin-33 and interleukin-18 serum levels in patients with rheumatoid arthritis and osteoporosis

open access: yesمجله دانشگاه علوم پزشکی بیرجند, 2014
Background and Aim: Limited studies have been focused on the role of IL-33 and IL-18 in Rheumatoid arthritis (RA).This study was done to measure the levels of IL-18 and IL-33 in the serum of patients with RA, before treatment, three month after ...
Ali Shahraki   +3 more
doaj  

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

open access: yesAdvanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave   +8 more
wiley   +1 more source

Interleukin (IL)-33: New Therapeutic Target for Atopic Diseases

open access: yes, 2014
.: Interleukin (IL)-33, a member of the IL-1 family of cytokines, is produced when epithelial and endothelial cells are exposed to stimuli. Hematopoietic cells such as macrophages also produce IL-33.
Takeshi Nabe
core   +1 more source

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