Results 251 to 260 of about 62,794,741 (290)

Interleukin-33 and the function of innate lymphoid cells

Trends in Immunology, 2012
Interleukin (IL)-33 is a member of the IL-1 cytokine family that has been shown to play an important role in the induction and effector phases of type 2 immune responses. Both innate and adaptive immunity are regulated by IL-33, and many studies have shown disease-associated functions for this cytokine.
Mirchandani, Ananda S., Salmond, Robert J., Liew, Foo Y.   +2 more
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Role of interleukin 33 in human immunopathology

Annals of the Rheumatic Diseases, 2010
Interleukin 33 (IL33) is a recently described member of the IL1 superfamily of cytokines. Originally defined on the basis of T-cell subset differentiation, IL33 is now recognised to mediate a wider role in regulating components of the innate immune response also, particularly via mast cell activation.
G E J, Murphy, D, Xu, F Y, Liew, I B, McInnes   +3 more
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Interleukin-33 and Atherosclerosis

2011
Interleukin (IL)-33 (also known as IL-1 F11) is a newly identified member of the IL-1 cytokine family with close amino acid sequence homology to IL-18 [1]. The human and mouse sequences for IL-33 have been mapped to chromosomes 9 (9p24.1) and 19 (19qc1), encoding proteins of 270 and 266 amino acids respectively.
Foo Y. Liew, Ashley M. Miller
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Interleukin-33: a regulator of basophils

Blood, 2009
The cytokine network controlling basophils has been extended to interleukin-33. This commentary provides an update and summary on this emerging concept.
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Association of serum interleukin‐33 level and the interleukin‐33 genetic variant with Japanese cedar pollinosis

Clinical & Experimental Allergy, 2008
Summary Background IL‐33, an IL‐1‐like cytokine, is a ligand for IL1RL1, which is an important effector molecule of type 2 T helper responses. Although IL‐33/IL1RL1 interaction has been suggested to be important in induction of allergic airway inflammation, serum levels of IL‐33 and the genetic
M, Sakashita, T, Yoshimoto, T, Hirota, M, Harada, K, Okubo, Y, Osawa, S, Fujieda, Y, Nakamura, K, Yasuda, K, Nakanishi, M, Tamari   +10 more
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Interleukin-33 in atopic dermatitis

Journal of Dermatological Science, 2019
Atopic dermatitis (AD) is characterized by pruritus, barrier disruption, and inflammationincluding type 2 cytokine production. Interleukin-33 (IL-33) is an inflammatory cytokine that is over-expressed in the keratinocytes of patients with AD. IL-33 transgenic mice, which express IL-33 specifically in keratinocytes, spontaneously develop AD-like eczema,
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Interleukin-33 and oxidative stress in epilepsy patients

Epilepsy Research, 2021
İnflammation and oxidative stress plays an important role in the etiology of epilepsy. Interleukin-33 (IL-33), a new member of the cytokine family associated with interleukin-1 (IL-1), has been found to play a role in pathogenesis of central nervous system diseases and cause the production of proinflammatory cytokines and oxidative stress molecules ...
Ozlem Ethemoglu, Mustafa Calık, Ismail Koyuncu, Kadri Burak Ethemoglu, Adalet Göcmen, Ahmet Güzelcicek, Dursun Cadırcı   +6 more
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Interleukin-33 as a New Marker of Pulmonary Sarcoidosis

2015
The mechanisms of sarcoidosis (Besniera-Boeck-Schaumann disease, BBS) remain incompletely understood, although recent observations suggested an important contribution of interleukin-33 (IL-33). So far, there are no data about bronchoalveolar lavage fluid (BALF) concentration of IL-33 in patients with BBS. In the present study we attempted to relate the
W, Naumnik, B, Naumnik, W, Niklińska, M, Ossolińska, E, Chyczewska   +4 more
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Tranilast inhibits interleukin-33 production by macrophages

European Journal of Pharmacology, 2018
Tranilast is an anti-allergy medication that inhibits the release of chemical mediators such as histamine. However, the mechanisms underlying its anti-allergy effects are not fully understood. Interleukin (IL)-33, a novel member of the IL-1 cytokine family, promotes T helper type 2 immune responses and plays a pathogenic role in allergic disorders.
Sachiko, Hiraide, Yoshiki, Yanagawa, Kenji, Iizuka   +2 more
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Upregulation of Interleukin-33 in obstructive renal injury

Biochemical and Biophysical Research Communications, 2016
Interstitial fibrosis and loss of parenchymal tubular cells are the common outcomes of progressive renal diseases. Pro-inflammatory cytokines have been known contributing to the damage of tubular cells and fibrosis responses after renal injury. Interleukin (IL)-33 is a tissue-derived nucleus alarmin that drives inflammatory responses.
Wei-Yu Chen, Ya-Jen Chang, Chia-Hao Su, Tzu-Hsien Tsai, Shang-Der Chen, Chung-Hsi Hsing, Jenq-Lin Yang   +6 more
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