Acute and chronic impact of interleukin-33 stimulation on chemokines and growth factors in human cord blood-derived mast cells. [PDF]
Bakhashab S +7 more
europepmc +1 more source
Interleukin-33 links asthma to alopecia areata: Mendelian randomization and mediation analysis.
Wu P +6 more
europepmc +1 more source
The Interleukin 33-T Helper 2 Cell Axis Promotes Human Liver Fibrosis. [PDF]
Lurje I, Tacke F.
europepmc +1 more source
Inhibition of Interleukin-33 to Reduce Glomerular Endothelial Inflammation in Diabetic Kidney Disease. [PDF]
Hofherr A +15 more
europepmc +1 more source
Low Secretory Leukocyte Protease Inhibitor (SLPI)-Level Potentiates Alternaria Extract-Induced T-Helper 2 (Th2) Airway Inflammation via the Interleukin-33 (IL-33) Pathway. [PDF]
Hirano T +4 more
europepmc +1 more source
Interleukin-33 promotes intrauterine adhesion formation in mice through the mitogen-activated protein kinase signaling pathway. [PDF]
Liu D +8 more
europepmc +1 more source
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Interleukin-33 in health and disease
Nature Reviews Immunology, 2016Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now, evidence is accumulating that IL-33 also potently stimulates group 2 innate lymphoid cells (ILC2s), regulatory T (Treg) cells, TH1 cells, CD8+ T cells and natural killer (NK ...
Foo Yew, Liew +2 more
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Interleukin-33: increasing role in dermatological conditions
Archives of Dermatological Research, 2016Interleukin-33 is a novel and an unconventional member of IL-1 family. It is an inflammation-induced factor with dual function exercising its role as an intracellular regulator of gene expression, as well as, an extracellular alarm mediator. It is a ligand for ST2, a heterodimeric membrane-bound receptor of the orphan IL-1 family receptor.
Balato, Anna +4 more
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Interleukin-33 in atopic dermatitis
Journal of Dermatological Science, 2019Atopic dermatitis (AD) is characterized by pruritus, barrier disruption, and inflammationincluding type 2 cytokine production. Interleukin-33 (IL-33) is an inflammatory cytokine that is over-expressed in the keratinocytes of patients with AD. IL-33 transgenic mice, which express IL-33 specifically in keratinocytes, spontaneously develop AD-like eczema,
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