Advanced Science, EarlyView.An engineered peptide self‐assembled nanofiber platform, designed to replicate STING–cGAMP binding motifs, facilitates pH‐responsive cytosolic delivery of cGAMP, enhances the endoplasmic reticulum with high efficiency, and robustly activates the STING pathway.
Yubin He +6 more
wiley +1 more source
Predictive value of serum interleukin-33 and thymic stromal lymphopoietin for the risk of acute exacerbation in patients with chronic obstructive pulmonary disease. [PDF]
Front Med (Lausanne)Yin S, Xu K, Wu S, Liu H, Ding Z.
europepmc +1 more source
Interleukin-33 promotes lipolysis of adipocytes and protects male mice against obesity via activation of β-adrenergic receptor signaling. [PDF]
Int J Obes (Lond)Chen Q +6 more
europepmc +1 more source
Diagnostic and monitoring value of serum interleukin-33 and rs16924159 polymorphism in relation to disease activity and tumor necrosis factor inhibitor response in rheumatoid arthritis. [PDF]
J Rheum DisKamel AH, Abbas AA, Alosami MH.
europepmc +1 more source
Partial reduction of interleukin-33 signaling improves senescence and renal injury in diabetic nephropathy. [PDF]
MedComm (2020)Chen L +15 more
europepmc +1 more source
Interleukin-33 links asthma to alopecia areata: Mendelian randomization and mediation analysis.
Skin Res TechnolWu P +6 more
europepmc +1 more source
Interleukin-33 in Health and Disease
Nature Reviews Immunology, 2016 Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now, evidence is accumulating that IL-33 also potently stimulates group 2 innate lymphoid cells (ILC2s), regulatory T (Treg) cells, TH1 cells, CD8+ T cells and natural killer (NK ...
Heth R. Turnquist +2 more
exaly +4 more sources
Interleukin-33: increasing role in dermatological conditions
Archives of Dermatological Research, 2016 Interleukin-33 is a novel and an unconventional member of IL-1 family. It is an inflammation-induced factor with dual function exercising its role as an intracellular regulator of gene expression, as well as, an extracellular alarm mediator. It is a ligand for ST2, a heterodimeric membrane-bound receptor of the orphan IL-1 family receptor.
Balato, Anna +4 more
openaire +6 more sources
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Interleukin-33 Safeguards Neutrophils in Sepsis
Nature Medicine, 2010Cytokines have a fundamental role in orchestrating innate immune responses to bacterial infections. Interleukin-33 (IL-33) is now shown to protect from sepsis by promoting neutrophil influx into the focus of infection (pages 708–712).
Thierry Roger, Thierry Calandra
exaly +3 more sources