Results 241 to 250 of about 2,248,771 (288)

Oncogenic KRAS-Dependent Stromal Interleukin-33 Directs the Pancreatic Microenvironment to Promote Tumor Growth. [PDF]

Cancer Discov
Donahue KL, Watkoske HR, Kadiyala P, Du W, Brown K, Scales MK, Elhossiny AM, Espinoza CE, Lasse Opsahl EL, Griffith BD, Wen Y, Sun L, Velez-Delgado A, Renollet NM, Morales J, Nedzesky NM, Baliira RK, Menjivar RE, Medina-Cabrera PI, Rao A, Allen B, Shi J, Frankel TL, Carpenter ES, Bednar F, Zhang Y, Pasca di Magliano M.   +26 more
europepmc   +1 more source

Soluble interleukin-33 receptor (sST-2): a novel marker for assessing cardiovascular risk in rheumatoid arthritis. [PDF]

J Circ Biomark
Claus I, Hoffmeister M, Remus C, Dammermann W, Gioti O, Ritter O, Patschan D, Patschan S.   +7 more
europepmc   +1 more source

Phase I Study of the Anti-interleukin 33 Fragment Antigen-Binding Region RO7303359 in Geographic Atrophy Secondary to Age-Related Macular Degeneration. [PDF]

Ophthalmol Sci
Pearlman JA, Sheth VS, Khanani AM, Indjeian VB, Brunstein F, Kuruvilla D, Maia M, Dere R, Ma L, Chen H, Datta S, Willis JR, Wiley HE.   +12 more
europepmc   +1 more source

Interleukin-33 links asthma to alopecia areata: Mendelian randomization and mediation analysis.

Skin Res Technol
Wu P, Tian K, Gao S, Jia Z, Xu W, Wang X, Wu L.   +6 more
europepmc   +1 more source

Interleukin-33 in health and disease

Nature Reviews Immunology, 2016
Interleukin-33 (IL-33) - a member of the IL-1 family - was originally described as an inducer of type 2 immune responses, activating T helper 2 (TH2) cells and mast cells. Now, evidence is accumulating that IL-33 also potently stimulates group 2 innate lymphoid cells (ILC2s), regulatory T (Treg) cells, TH1 cells, CD8+ T cells and natural killer (NK ...
Foo Yew, Liew, Jean-Philippe, Girard, Heth Roderick, Turnquist   +2 more
openaire   +3 more sources

Interleukin-33: increasing role in dermatological conditions

Archives of Dermatological Research, 2016
Interleukin-33 is a novel and an unconventional member of IL-1 family. It is an inflammation-induced factor with dual function exercising its role as an intracellular regulator of gene expression, as well as, an extracellular alarm mediator. It is a ligand for ST2, a heterodimeric membrane-bound receptor of the orphan IL-1 family receptor.
Balato, Anna, Raimondo, Annunziata, Balato, Nicola, Ayala, Fabio, LEMBO, Serena   +4 more
openaire   +6 more sources

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Role of interleukin 33 in human immunopathology

Annals of the Rheumatic Diseases, 2010
Interleukin 33 (IL33) is a recently described member of the IL1 superfamily of cytokines. Originally defined on the basis of T-cell subset differentiation, IL33 is now recognised to mediate a wider role in regulating components of the innate immune response also, particularly via mast cell activation.
G E J, Murphy, D, Xu, F Y, Liew, I B, McInnes   +3 more
openaire   +2 more sources

Association of serum interleukin‐33 level and the interleukin‐33 genetic variant with Japanese cedar pollinosis

Clinical & Experimental Allergy, 2008
SummaryBackground IL‐33, an IL‐1‐like cytokine, is a ligand for IL1RL1, which is an important effector molecule of type 2 T helper responses. Although IL‐33/IL1RL1 interaction has been suggested to be important in induction of allergic airway inflammation, serum levels of IL‐33 and the genetic influences of the polymorphisms of IL‐33 in human ...
M, Sakashita, T, Yoshimoto, T, Hirota, M, Harada, K, Okubo, Y, Osawa, S, Fujieda, Y, Nakamura, K, Yasuda, K, Nakanishi, M, Tamari   +10 more
openaire   +2 more sources

Interleukin-33 and Atherosclerosis

2011
Interleukin (IL)-33 (also known as IL-1 F11) is a newly identified member of the IL-1 cytokine family with close amino acid sequence homology to IL-18 [1]. The human and mouse sequences for IL-33 have been mapped to chromosomes 9 (9p24.1) and 19 (19qc1), encoding proteins of 270 and 266 amino acids respectively.
Foo Y. Liew, Ashley M. Miller
openaire   +1 more source

Interleukin-33: a regulator of basophils

Blood, 2009
The cytokine network controlling basophils has been extended to interleukin-33. This commentary provides an update and summary on this emerging concept.
openaire   +2 more sources