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Interleukin-38 overexpression prevents bleomycin-induced mouse pulmonary fibrosis
Naunyn-Schmiedeberg's Archives of Pharmacology, 2020Pulmonary fibrosis is a kind of pulmonary disorder with chronic inflammation and excessive collagen deposition, and its etiology is not clear. Interleukin (IL)-38 is a new member of IL-1 family cytokines, but its role in pulmonary fibrosis has not been elucidated.
Zhiwei Xu +4 more
semanticscholar +4 more sources
Interleukin-38 is elevated in inflammatory bowel diseases and suppresses intestinal inflammation.
Cytokine, 2020There has been no report investigating the role of IL-38 in inflammatory bowel diseases (IBD). Therefore, we investigated the expression of IL-38 in IBD patients and its role in regulating intestinal inflammation. The levels of IL-38 were significantly elevated in the intestine of IBD patients and DSS-induced colitis mice.
Cheng Xie +6 more
semanticscholar +3 more sources
Interleukin-38 increases the insulin sensitivity in children with the type 2 diabetes.
International Immunopharmacology, 2020The prevalence of type 2 diabetes mellitus (DM) is increasing in the children population. It is well known that inflammation contributes to the type 2 DM pathogenesis. Interleukin 38 (IL-38) is one newly identified anti-inflammatory factor. Therefore, we investigated whether the expression level of IL-38 is associated with type 2 DM in the children and
Y. Liu +4 more
semanticscholar +3 more sources
Plasma interleukin‐38 in patients with rheumatoid arthritis
International Immunopharmacology, 2018Previous studies have indicated that interleukin-38 (IL-38) is involved in rheumatoid arthritis (RA). The present study aims to assess plasma levels of IL-38 in RA and discuss the potential of IL-38 as a biomarker for RA. Protein concentrations of IL-38 were examined by enzyme-linked immunosorbent assay, and the mRNA level of IL-38 was tested by ...
Wang-Dong Xu +3 more
semanticscholar +4 more sources
Interleukin‐38 inhibits adipogenesis and inflammatory cytokine production in 3T3‐L1 preadipocytes
Cell Biology International, 2020Interleukin‐38 (IL‐38) is a novel member of the IL‐1 cytokine family with anti‐inflammatory activity. However, its effect on adipogenesis and inflammatory cytokines secretion of adipocytes in vitro has not been reported. To address whether IL‐38 inhibits
Yan Li +4 more
semanticscholar +3 more sources
Plasma levels of interleukin-38 in healthy aging and in type 2 diabetes.
Diabetes Research and Clinical Practice, 2020Plasma levels of interleukin (IL)-38 were evaluated in patients with type 2 diabetes (T2DM) and healthy controls. Plasma IL-38 was higher in T2DM patients and positively related to waist/hip ratio, HbA1c, uric acid, liver function tests, triglycerides and total proteins. Patients suffering from diabetic nephropathy had the highest IL-38 levels.
Felicia Gurău +6 more
semanticscholar +4 more sources
A Prospective Study to Assess The Role of Interleukin-38 in Inflammatory Bowel Disease
, 2021This thesis examines the role of Interleukin-38 in inflammatory bowel disease (IBD), a gastrointestinal condition that impacts patient's quality of life. Interleukin-38 is a new molecule in its early research phase. In my thesis, I found that there is an
Manjeet K. Sandhu
semanticscholar +3 more sources
Journal of Interferon & Cytokine Research, 2021
The aim of this study was to assess interleukin-1β (IL-1β), IL-1Ra, IL-36, and IL-38 levels together with hs-CRP levels in patients with different radiographic grades of knee osteoarthritis (OA) in comparison to healthy individuals.
Baver Akcan Duman +4 more
semanticscholar +5 more sources
The aim of this study was to assess interleukin-1β (IL-1β), IL-1Ra, IL-36, and IL-38 levels together with hs-CRP levels in patients with different radiographic grades of knee osteoarthritis (OA) in comparison to healthy individuals.
Baver Akcan Duman +4 more
semanticscholar +5 more sources
Serum levels of interleukin-38 in sufferers with atopic eczema
Egyptian Journal of Dermatology and Venerology, 2019Background The relation between interleukin-38 (IL-38) and atopy is not precisely regarded yet. The current study has a look at set to assess the serum level of IL-38 in atopy patients and controls in order to illustrate the disease association and ...
Fathia M Khattab +2 more
semanticscholar +3 more sources
Journal of Interferon and Cytokine Research, 2021
Inflammatory cytokines has been of great interest in the field of colorectal cancer (CRC) tumor immunology in recent years. As an anti-inflammatory interleukin (IL), IL-38 may contribute to the early diagnosis of CRC and improve the prognosis of CRC ...
Lifeng Huang +4 more
semanticscholar +1 more source
Inflammatory cytokines has been of great interest in the field of colorectal cancer (CRC) tumor immunology in recent years. As an anti-inflammatory interleukin (IL), IL-38 may contribute to the early diagnosis of CRC and improve the prognosis of CRC ...
Lifeng Huang +4 more
semanticscholar +1 more source