Results 101 to 110 of about 13,619,962 (300)

Interleukin-6 gene (IL-6): a possible role in brain morphology in the healthy adult brain [PDF]

, 2012
Background: Cytokines such as interleukin 6 (IL-6) have been implicated in dual functions in neuropsychiatric disorders. Little is known about the genetic predisposition to neurodegenerative and neuroproliferative properties of cytokine genes.
Domschke, Katharina, Volker Arolt, Walter Heindel, Katharina Domschke, Schoening, Sonja, Bernhard T Baune, Jochen Bauer, Christina Uhlmann, Arolt, V, Heindel, W., Konrad, Carsten, Domschke Katharina, Rauch, AV, Konrad Carsten, Suslow Thomas, Sonja Schöning, Kugel, H., Kugel, Harald, Heindel, W, Heindel, Walter, Konrad, C, Domschke, K, Uhlmann, C., Birosova, E, Udo Dannlowski, Suslow, T., Konrad, C., Baune, Bernhard T., Ohrmann Patricia, Uhlmann, C, Grotegerd Dominik, Patricia Ohrmann, Thomas Suslow, Ohrmann, P, Baune, B., Harald Kugel, Rauch, Astrid V., Astrid V Rauch, Grotegerd, D., Birosova Eva, Dannlowski Udo, Rauch Astrid V, Dannlowski, U, Kugel Harald, Birosova, E., Bauer, Jochen, Grotegerd, D, Grotegerd, Dominik, Arolt Volker, Rauch, A., Suslow, T, Uhlmann Christina, Dannlowski, U., Schöning Sonja, Bauer, J., Eva Birosova, Ohrmann, Patricia, Suslow, Thomas, Birosova, Eva, Kugel, H, Bauer, J, Ohrmann, P., Carsten Konrad, Schoning, S., Baune Bernhard T, Schöning, Sonja, Arolt, Volker, Arolt, V., Uhlmann, Christina, Dannlowski, Udo, Bauer Jochen, Domschke, K., Dominik Grotegerd, Baune, BT, Heindel Walter, Schöning, S   +75 more
core   +2 more sources

Prostaglandin D2 and Interleukin-5 Reduce Crth2 Surface Expression on Human Eosinophils

Allergology International, 2004
Background: Recently, a second prostaglandin D2 (PGD2) receptor, chemoattractant receptor-homologous molecule expressed on Th2 cells (CRTH2), was identified.
Kazuyuki Hamada, Yoshiyuki Yamada, Yumiko Kamada, Shigeharu Ueki, Kazutoshi Yamaguchi, Hajime Oyamada, Miyoshi Fujita, Atsuko Usami, Takahito Chiba, Akira Kanda, Hiroyuki Kayaba, Junichi Chihara   +11 more
doaj   +1 more source

Predictive Value of Composite Inflammatory Markers for Stroke Prognosis: A Prospective Cohort Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Novel composite inflammatory markers' role in stroke prognosis is understudied, and the best predictor is unclear, requiring further exploration. Objectives This study aimed to systematically evaluate the associations of 6 novel composite inflammatory markers on stroke prognosis.
Bing Wu, Jie‐Jie Li, Jing Jing, Jin‐Xi Lin, Xia Meng, Yong Jiang, Yong‐Jun Wang, Hong‐Qiu Gu   +7 more
wiley   +1 more source

Sepsis beim Hund: Interleukin-6 als prognostischer Parameter [PDF]

, 2007
Wie auch in der Humanmedizin stellen Sepsis und SIRS den behandelnden Arzt in der Veterinärmedizin vor eine große Herausforderung. Eine optimale therapeutische Intervention setzt besonders die Früherkennung dieser Erkrankungen und damit auch die ...
Rau, Stefanie Maria
core   +1 more source

Cytokine Contents in Chronic Lymphocytic Leukemia: Association with ZAP70 Expression

Turkish Journal of Hematology, 2016
Objective: Chronic lymphocytic leukemia (CLL) is a disease that shows varying clinical progression, and expression of the protein tyrosine kinase ZAP70 has been described as a very valuable prognostic factor.
Nilgün Işıksaçan, Suzan Çınar, Esin Aktaş Çetin, Melih Aktan, Günnur Deniz   +4 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production pathway

, 2002
Granulomatous Diseases Review Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production ...
Kumararatne, D.S., Baretto, Richard, De Heer, E., J.F. EMILE, Ottenhoff, THM, De Heer, E, Edgar, JD, Binch, J., Ottenhoff, T.H., Casanova, J.L., Lammas, David, Lammas, D.A., Edgar, J, Kumararatne, DS, Panchalingam, S, Novelli, V., E. DE HEER, Drysdale, P, Binch, J, Ottenhoff, TH, Panchalingam, S., Emile, JF, Drysdale, Pamela, C. MACLENNAN, T. H. M. OTTENHOFF, Ben-smith, Anne, Novelli, V, P. DRYSDALE, MacLennan, Calman, R. BARETTO, Casanova, JL, J. BINCH, Ben-Smith, A., Casanova, J-L, Ben-Smith, A, Drysdale, P., Emile, J.F., D. S. KUMARARATNE, Baretto, R, Baretto, R., S. PANCHALINGAM, J.-L. CASANOVA, MacLennan, C, J. D. EDGAR, A. BEN-SMITH, Kumararatne, Dinakantha, D. A. LAMMAS, MacLennan, C., Lammas, David A, V. NOVELLI   +49 more
core   +1 more source

Retinal vascular calibers and correlations with biomarkers in bitches with pyometra-induced systemic inflammatory response syndrome [PDF]

Veterinary World
Background and Aim: Pyometra is a common uterine disease in intact bitches, frequently progressing to systemic inflammatory response syndrome (SIRS).
Fábio Dumit Pizzinatto, Alexandre Pinto Ribeiro, Bianca Eidt Rodrigues, Hanna Rodrigues Miranda, Nathalia de Assis Pereira   +4 more
doaj   +1 more source

CSF Cytokine Network Organization Predicts Progression Independent of Relapse and MRI Activity in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progression independent of relapse activity is a major determinant of long‐term disability in multiple sclerosis, but its immunopathologic basis remains incompletely understood. We investigated whether relapse‐independent progression in radiologically stable relapsing–remitting multiple sclerosis is associated with distinct ...
Antonio Bruno, Matteo Conti, Ettore Dolcetti, Federica Azzolini, Angela Borrelli, Roberta Fantozzi, Mario Stampanoni Bassi, Giovanni Galifi, Giuseppe Maccarrone, Luca Montaguti, Marco Cervigni, Maddalena Dal Pozzo, Roberto Furlan, Annamaria Finardi, Girolama Alessandra Marfia, Marco Salvetti, Antonella Conte, Fabio Buttari, Diego Centonze, Luana Gilio   +19 more
wiley   +1 more source

Endothelial Cell Proteins as Biomarkers in Susac Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin, Yue Andy Qi, Ying Hao, Catherine DeMarino, Samuel Darko, Irene Cortese, Daniel S. Reich, María I. Gaitán, Steven Jacobson, Bridgett J. Billioux, Bryan Smith, Avindra Nath   +11 more
wiley   +1 more source