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Bulletin du cancer, 1991
Human IL-4 is a mature 129 AA glycoprotein, mostly secreted by activated T cells. It is a pleiotropic cytokine which acts on T and B lymphocytes, monocytes, polymorphonuclear cells, fibroblasts and endothelial cells. In addition it acts at various stages of cell differentiation and its effects are also dependent on the cytokine environment.
J, Banchereau +4 more
openaire +1 more source
Human IL-4 is a mature 129 AA glycoprotein, mostly secreted by activated T cells. It is a pleiotropic cytokine which acts on T and B lymphocytes, monocytes, polymorphonuclear cells, fibroblasts and endothelial cells. In addition it acts at various stages of cell differentiation and its effects are also dependent on the cytokine environment.
J, Banchereau +4 more
openaire +1 more source
Journal of lipid mediators and cell signalling, 1994
Human IL-4 is a mature glycoprotein of 129 amino acids, mostly secreted by activated T cells. It is a pleiotropic cytokine which acts on T and B lymphocytes, monocytes, polymorphonuclears, fibroblasts and endothelial cells. In addition, it acts at various stages of cell differentiation, and its effects are also dependent on the cytokine environment. In
J, Banchereau +4 more
openaire +1 more source
Human IL-4 is a mature glycoprotein of 129 amino acids, mostly secreted by activated T cells. It is a pleiotropic cytokine which acts on T and B lymphocytes, monocytes, polymorphonuclears, fibroblasts and endothelial cells. In addition, it acts at various stages of cell differentiation, and its effects are also dependent on the cytokine environment. In
J, Banchereau +4 more
openaire +1 more source
Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity
Cancer Cell, 2022Yared Hailemichael +2 more
exaly
1995
Abstract Both the murine (Mosley et al. 1989) and human (ldzerda et al. 1990) IL-4 receptors have been molecularly cloned. The murine IL-4 receptor, which was cloned first (Mosley et al. 1989), is produced as an 810-amino-acid precursor with a predicted 25-amino-acid signal peptide (GenBank accession number M27959).
openaire +1 more source
Abstract Both the murine (Mosley et al. 1989) and human (ldzerda et al. 1990) IL-4 receptors have been molecularly cloned. The murine IL-4 receptor, which was cloned first (Mosley et al. 1989), is produced as an 810-amino-acid precursor with a predicted 25-amino-acid signal peptide (GenBank accession number M27959).
openaire +1 more source
Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19
New England Journal of Medicine, 2021Anthony C Gordon +2 more
exaly