Results 261 to 270 of about 14,230,992 (393)

Interleukin-4-Mediated NLRP3 Inflammasome Activation in Microglia Contributes to Allergic Rhinitis via Central Sensitization. [PDF]

Research (Wash D C)
Lv H, Wang Y, Tan L, Xie Y, Liu P, Guan M, Cong J, Xu Y.   +7 more
europepmc   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

Association of interleukin-4 polymorphisms with multiple sclerosis in southeastern Iranian patients

, 2012
Mohammad Kazemi Arababadi, Reza Mosavi, Ali Ravari, Hossein Teimori, Gholamhossein Hassanshahi   +4 more
openalex   +1 more source

Interleukin‐33 exacerbates acute colitis via interleukin‐4 in mice

Immunology, 2013
P. Pushparaj, Dong Li, M. Komai‐Koma, R. Guabiraba, J. Alexander, C. McSharry, Damo Xu   +6 more
semanticscholar   +1 more source

Interleukin-4 modulates type I interferon to augment antitumor immunity. [PDF]

Sci Adv
Newnes HV, Armitage JD, Buzzai AC, de Jong E, Audsley KM, Barnes SA, Srinivasan S, Serralha M, Fear VS, Guo BB, Jones ME, Forrest ARR, Foley B, Darcy PK, Beavis PA, Bosco A, Waithman J.   +16 more
europepmc   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

In vitro and in vivo evaluation of chemically synthesized, receptor-biased interleukin-4 and photocaged variants. [PDF]

Sci Adv
Ninomiya M, Egholm C, Breu D, Boyman O, Bode JW.   +4 more
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Immunity

Emerging Infectious Diseases, 2016
Theodore M. Lee
doaj   +1 more source

Interleukin-4 downregulates the cyclic tensile stress-induced matrix metalloproteinases-13 and cathepsin B expression by rat normal chondrocytes

, 2008
英之 土井
openalex   +1 more source