Results 281 to 290 of about 12,582,645 (332)

Bimetallic Peroxide Nanocomposites‐Driven Redox Dyshomeostasis to Activate Sequential Cuproptosis and Pyroptosis for Amplified Tumor Immunotherapy

Advanced Science, EarlyView.
Hyaluronic acid‐modified bimetallic peroxide nanocomposites (MgO2‐CuO2@HA) are designed for synergistic tumor therapy. The nanocomposites release Mg2+, H2O2, and Cu2+ in tumor cells, induce cuproptosis via Cu+‐mediated protein aggregation, and activate pyroptosis through caspase‐1/gasdermin D pathways for inducing immunogenic cell death, collectively ...
Guanting He, Haixia Zhu, Peipei Kang, Lili Feng, Chenghao Yu, Yanlin Zhu, Bin Liu, Zhengxiao Guo, Piaoping Yang   +8 more
wiley   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Evaluation of serum interleukin-12 and interleukin-4 as potential biomarkers for the diagnosis of major depressive disorder. [PDF]

Sci Rep
Sarmin N, Roknuzzaman ASM, Mouree TZ, Islam MR, Al Mahmud Z.   +4 more
europepmc   +1 more source

Interleukin-4 Modulates Neuroinflammation by Inducing Phenotypic Transformation of Microglia Following Subarachnoid Hemorrhage. [PDF]

Inflammation
Wang J, Wang L, Wu Q, Cai Y, Cui C, Yang M, Sun B, Mao L, Wang Y.   +8 more
europepmc   +1 more source

Correction: Olteanu et al. <i>Interleukin-4</i> Gene Polymorphisms in Romanian Patients with Inflammatory Bowel Diseases: Association with Disease Risk and Clinical Features. <i>Diagnostics</i> 2023, <i>13,</i> 1465. [PDF]

Diagnostics (Basel)
Olteanu AO, Ionescu EM, Tieranu CG, Popa LO, Andrei SI, Preda CM, Dutescu MI, Bojinca M, Tieranu I, Popa OM.   +9 more
europepmc   +1 more source

Long-term interleukin-4 release from 3D printable affinity hydrogels promotes M2-like macrophage polarisation <i>in vitro</i>.

Biomater Sci
Loxley GA, Coser C, Ghaemmaghami AM, Yang J.   +3 more
europepmc   +1 more source

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Interleukin-4

Definitions, 2020
openaire   +2 more sources

Interleukin 4

International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology, 1990
Since its discovery in 1982, numerous biological activities of interleukin-4 (IL-4) have been described. Like other cytokines, IL-4 is highly pleiotropic, both with respect to the number of different target cells that are responsive to it and with respect to the number of different biological responses it elicits.
J H, Jansen, W E, Fibbe, R, Willemze, J C, Kluin-Nelemans   +3 more
  +6 more sources

Interleukin‐4 and listeriosis

Immunological Reviews, 1997
Summary: Experimental infection of mice with Listeria monocytogenes (L. monocytogenes) has served as an appropriate model for analyzing Thl nil driven immune responses. Generally, Th2 responses are absent and IL‐4 is not detectable. Here, we describe experimental settings under which IL‐4 is detectable in listeriosis.
Kaufmann, S., Emoto, M., Szalay, G., Barsig, J., Flesch, I.   +4 more
openaire   +3 more sources