Results 81 to 90 of about 657,596 (286)
Modulation by IL-10 of antigen-induced allergic responses in mice
Memorias do Instituto Oswaldo Cruz, 1997 Over the last few years, we examined the anti-allergic properties of interleukin (IL)-10 in different models of inflammation in the mouse, as well as against IgE-dependent activation of mouse bone marrow-derived mast cells (BMMC).
Claudia Zuany-Amorim +2 more
doaj +1 more source
Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin +2 more
wiley +1 more source
Th2 cytokines and asthma — The role of interleukin-5 in allergic eosinophilic disease
Respiratory Research, 2001 Interleukin-5 is produced by a number of cell types, and is responsible for the maturation and release of eosinophils in the bone marrow. In humans, interleukin-5 is a very selective cytokine as a result of the restricted expression of the interleukin-5 ...
Chapman Richard W +4 more
doaj +1 more source
Drugs in Context, 2019 Background: Asthma is an inflammatory disease of the airways with symptoms that vary over time and intensity, sometimes leading to disability or even death. Eosinophilic asthma accounts for 25% of cases of severe asthma.
Olalla Montero-Pérez +2 more
doaj +1 more source
Pollen grains induce a rapid and biphasic eczematous immune response in atopic eczema patients [PDF]
, 2008 Introduction: Eczematous reactions to type I allergy-inducing antigens are documented in a subgroup of patients with atopic eczema. Yet, the underlying immunological mechanisms are not well understood.
Behrendt, Heidrun +7 more
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Selective suppression of leukocyte recruitment in allergic inflammation
Memorias do Instituto Oswaldo Cruz, 2005 Allergic diseases result in a considerable socioeconomic burden. The incidence of allergic diseases, notably allergic asthma, has risen to high levels for reasons that are not entirely understood.
CL Weller, PJ Jose, TJ Williams
doaj +1 more source
Clinical efficacy of mepolizumab in the treatment of severe eosinophilic asthma in children
Медицинский совет, 2020 Severe bronchial asthma in children remains a serious problem, which is caused by high mortality, side effects from therapy with high doses of glucocorticosteroids and a significant consumption of health resources.
V. N. Drozdov +4 more
doaj +1 more source
Genome-wide association studies of inflammatory bowel disease in German shepherd dogs [PDF]
, 2018 Canine Inflammatory Bowel Disease (IBD) is considered a multifactorial disease caused by complex interactions between the intestinal immune system, intestinal microbiota and environmental factors in genetically susceptible individuals.
Allenspach, Karin +7 more
core +6 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source