Results 151 to 160 of about 8,039,165 (298)

Interleukin-8-driven monocyte activation in primary sclerosing cholangitis: Insights from single-cell analysis and humanized immune system mice. [PDF]

open access: yesJHEP Rep
Heyerick L   +20 more
europepmc   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

open access: yesAdvanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao   +8 more
wiley   +1 more source

Association of interleukin-8 and neutrophil-to-lymphocyte ratio with clinical indices in diabetic nephropathy. [PDF]

open access: yesCaspian J Intern Med
Freidoon M   +7 more
europepmc   +1 more source

Identification of an Osteochondral Erosion Process in Gout Driven by Fibrinogen‐Integrin Activation and Local MSU Crystallization

open access: yesAdvanced Science, EarlyView.
Cartilage injury promotes local fibrinogen deposition, which accelerates monosodium urate crystallization and activates integrin‐mediated matrix‐degradation. This self‐amplifying cycle drives gout‐related cartilage erosion. Disrupting fibrinogen deposition or restoring the cartilage barrier could interrupt this vicious cycle.
Hanlin Xu   +7 more
wiley   +1 more source

Diagnostic value of interleukin-8 in colon cancer: Prospective, case-control study. [PDF]

open access: yesWorld J Gastrointest Surg
Güneş G   +3 more
europepmc   +1 more source

Targeting p21‐High Senescent Kupffer Cells Nanotherapeutically Potentiates Antitumor Immunity in Advanced Hepatocellular Carcinoma with Portal Vein Tumor Thrombus

open access: yesAdvanced Science, EarlyView.
Schematic illustration of a biomimetic SKEV@AAV platform targeting p21‐high senescent Kupffer cells (sKCs) in hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT). p21‐high sKCs accumulate in the PVTT microenvironment and establish an immunosuppressive, SASP‐rich environment that facilitates tumor cell proliferation and immune evasion.
Na Ta   +10 more
wiley   +1 more source

Interleukin-10/Interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family history

open access: yes, 2009
Interleukin-10/Interleukin-5 responses at birth predict risk for respiratory infections in children with atopic family ...
M Kusel (10012535)   +7 more
core  

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

open access: yesAdvanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li   +13 more
wiley   +1 more source

Correlation of serum interleukin-8 with disease severity in aplastic anemia. [PDF]

open access: yesHematol Transfus Cell Ther
Sabir SF, Abd Al-Lateef HI, Hamza NA.
europepmc   +1 more source

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