Results 111 to 120 of about 1,003,113 (304)

In vitro generation of regulatory T cells: A challenging tool for studying immune aging in humans

FEBS Open Bio, EarlyView.
In vitro induction of human regulatory T cells using standard protocols generates suppressive, Foxp3‐expressing CD4+ T cells independently of TGF‐β supplementation and donor age. Regulatory T (Treg) cells play a key role in immune tolerance and homeostasis.
Lynn Muller, Jana Bleher, Birgit Weinberger, Lourdes Rocamora‐Reverte   +3 more
wiley   +1 more source

Median level of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), interleukin-12p70 (IL-12p70), interleukin-17A (IL-17A), tumour necrosis factor alfa (TNF-α) and interferon gamma (IFN-γ) of study participant’s plasma samples.

, 2020
Median level of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-6 (IL-6), interleukin-8 (IL-8), interleukin-10 (IL-10), interleukin-12p70 (IL-12p70), interleukin-17A (IL-17A), tumour necrosis factor alfa (TNF-α) and interferon gamma (IFN-γ) of ...
Robert Nowak (6748448), Dorota Kostrzewa-Nowak (8367930)   +1 more
core   +1 more source

Antioxidant and anti-inflammatory activity by modulating IL-6 as a potential mechanism in the nephroprotective and hepatoprotective properties of Tribulus terrestris

Research in Pharmaceutical Sciences
Background and purpose: Carboplatin, a second-generation platinum-containing compound is associated with renal tubular injury and hepatic damage in cancer patients.
Neha Shetty, Sadhana Holla, Veena Nayak, Vijetha B Shenoy, Rao KG Mohandas   +4 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Interleukin signaling in the regulation of natural killer cells biology in breast cancer

Frontiers in Immunology
In the field of breast cancer treatment, the immunotherapy involving natural killer (NK) cells is increasingly highlighting its distinct potential and significance.
Jiachi Xu, Jiachi Xu, Hongyu Gao, Hongyu Gao, Muhammad Salman Azhar, Haifan Xu, Siyuan Chen, Mingcan Li, Xinxi Ni, Ting Yan, Hui Zhou, Qian Long, Qian Long, Wenjun Yi, Wenjun Yi   +14 more
doaj   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source

Interleukin-6 levels in selected 12 plasma sample before and after apo-B depletion.

Interleukin-6 levels in selected 12 plasma sample before and after apo-B depletion.
Chin-Sung Kuo (8878307), Kai-Lee Chen (18349731), Ruey-Hsing Chou (5029544), Po-Hsun Huang (183737), Chun-Chin Chang (6315131), Jih-Hua Wei (18349734), Shing-Jong Lin (174700)   +6 more
core   +1 more source

Ethyl acetate extract of fungus comb from Malayan termite (Macrotermes gilvus Hagen) mound modulates splenic inflammatory responses in mice

Open Veterinary Journal
Background: The fungus comb is a unique structure inside termites' nests that facilitates the growth of Termitomyces sp. as a nutrient source for the termites. It is known to possess immunomodulatory properties that boost the immune system.
Hermawan Susanto, Jeferson Caesario, Decsa Medika Hertanto, Ketut Sudiana, Kukuh Dwiputra Hernugrahanto, Dwikora Novembri Utomo, Nicolaas Cyrillus Budhiparama, Ahmad Dzulfikri Nurhan, Mahardian Rahmadi, Dodi Nandika, Lina Karlinasari, Arinana Arinana, Irmanida Batubara, Lucia Dhiantika Witasari, Yanti Rachmayanti, Dikhi Firmasyah, Sairah Abdul Karim, Indang Ariati Ariffin, Djoko Santoso   +18 more
doaj   +1 more source

Effects of Add‐On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand, Seyed Hossein Aghamiri, Saeed Mohmammad Soleymani, Shadiyeh Bararpoor Poshkohi, Samaneh Masoudi, Hadi Esmaily   +5 more
wiley   +1 more source

A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]

, 2004
Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Kabesch, Michael, Stachel, Daniel, Carr, David, Schmid, Irene, Woitsch, Bernd, Weiland, Stephan K., Fritzsch, Christian, Mutius, Erika von   +7 more
core   +1 more source