Interleukin-8: An evolving chemokine.
K. Matsushima, De Yang, J. Oppenheim
semanticscholar +1 more source
Metabolic Consequences of Rheumatoid Arthritis
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry+2 more
wiley +1 more source
Specific low frequency electromagnetic fields induce epigenetic and functional changes in U937 cells [PDF]
In this study, we investigated the effects of specific low frequency electromagnetic fields sequences on U937 cells, an in vitro model of human monocyte/macrophage differentiation. U937 cells were exposed to electromagnetic stimulation by means of the SyntheXer system using two similar sequences, XR-BC31 and XR-BC31/F.
arxiv
Glucocorticoids inhibit transcriptional and post-transcriptional expression of interleukin 1 in U937 cells. [PDF]
Peter Juel Thiis Knudsen+2 more
openalex +1 more source
Interleukin-22 Promotes Intestinal Stem Cell-Mediated Epithelial Regeneration
Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. The intestinal stem cell (ISC) niche provides Wnt, Notch and epidermal growth factor (EGF) signals supporting Lgr5+ crypt base columnar ISCs for ...
C. Lindemans+26 more
semanticscholar +1 more source
Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu+6 more
wiley +1 more source
A reaction-diffusion model for relapsing-remitting multiple sclerosis with a treatment term [PDF]
We present a mathematical study for the development of multiple sclerosis based on a reaction-diffusion system. The model describes interactions among different populations of human cells, motion of immune cells stimulated by cytokines, consumption of myelin sheath due to anomalously activated lymphocytes and its restoration by oligodendrocytes ...
arxiv
Personalized Mathematical Model Predicting Endotoxin-Induced Inflammatory Responses in Young Men [PDF]
The initial reaction of the body to pathogenic microbial infection or severe tissue trauma is an acute inflammatory response. The magnitude of such a response is of critical importance, since an uncontrolled response can cause further tissue damage, sepsis, and ultimately death, while an insufficient response can result in inadequate clearance of ...
arxiv
Glioblastoma cells release interleukin 1 and factors inhibiting interleukin 2-mediated effects. [PDF]
A. Fontana+3 more
openalex +1 more source
A multifunctional hydroxyapatite (HAp) coating integrated with silver‐gallium liquid metal nanoparticles (HAp‐Ag‐GaNPs) exhibits dual antibacterial and osteogenic properties. It effectively inhibits Gram‐positive and Gram‐negative bacteria, including resistant strains, while enhancing bone regeneration.
Ngoc Huu Nguyen+17 more
wiley +1 more source