Results 131 to 140 of about 1,297,479 (340)

Interleukin signaling [PDF]

open access: yesCurrent Biology, 2002
Vosshenrich, Christian A. J.   +1 more
openaire   +3 more sources

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

open access: yesAdvanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai   +9 more
wiley   +1 more source

Double Cross‐Linked Hydrogel for Intra‐articular Injection as Modality for Macrophages Metabolic Reprogramming and Therapy of Rheumatoid Arthritis

open access: yesAdvanced Functional Materials, EarlyView.
A hydrogel for intra‐articular injection for the treatment of rheumatoid arthritis (RA) is formulated and comprehensively studied. After administration, the hydrogel induces a metabolic reprogramming of immunometabolism of macrophages to trigger fatty acid oxidation subsequently inducing polarization of anti‐inflammatory M2 macrophages. This results in
Yutong Song   +8 more
wiley   +1 more source

High‐Throughput Microfluidic‐Mediated Assembly of Layer‐By‐Layer Nanoparticles

open access: yesAdvanced Functional Materials, EarlyView.
The layer‐by‐layer (LbL) assembly of polymer films on nanoparticle (NP) surfaces is a promising technique for targeted drug delivery. Despite its success in preclinical mouse models, a current good manufacturing practices (cGMP) compliant, clinical‐scale production method has been lacking.
Ivan S. Pires   +4 more
wiley   +1 more source

SALIVARY BIOMARKERS LEVELS ACCORDING TO THE PERIODONTAL STATUS – REVIEW

open access: yesRomanian Journal of Medical and Dental Education, 2019
Sampling of saliva is simple and effective. It is a simple method in that it does not require expertise for collection and is less expensive. Periodontal disease is a chronic microbial and inflammatory process characterized by the presence of pathogenic ...
Dora Maria Popescu   +5 more
doaj  

Defective gamma interferon production in leprosy. Reversal with antigen and interleukin 2. [PDF]

open access: bronze, 1983
N Nogueira   +9 more
openalex   +1 more source

A Bioengineered Model of the Human Cornea for Preclinical Assessment of Human Ocular Exposure to Environmental Toxicants

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This paper presents a microphysiological system containing an array of individually addressable living corneal tissues constructed using primary human cells. The bioengineered eye model can simulate acute exposure of the human cornea to different types of environmental toxicants and provides a novel platform for visualization and quantitative ...
Se‐jeong Kim   +12 more
wiley   +1 more source

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