Results 291 to 300 of about 1,016,945 (361)

Immunologic Profiling of CSF in Subarachnoid Neurocysticercosis Reveals Specific Interleukin-10-Producing Cell Populations During Treatment. [PDF]

Neurol Neuroimmunol Neuroinflamm
Tang NL, Schaughency P, Gazzinelli-Guimaraes P, Lack J, Thumm L, Miltenberger E, Nash TE, Nutman TB, O'Connell EM.   +8 more
europepmc   +1 more source

Restoring Histone Acetylation Accelerates Diabetic Wound Repair by Improving the Spatiotemporal Dynamics of Macrophages

Advanced Science, EarlyView.
Butyrate—via epigenetic modulation of the histone core—rebalance dysregulated macrophage function and promotes wound healing under persisting hostile conditions of diabetic mice. Additionally, butyrate harmonizes macrophage interactions with keratinocytes and fibroblasts as well as breaks the vicious cycle of inflammation in chronic wounds by restoring
Karmveer Singh, Albert Kallon Koroma, Rajeev Kumar Pandey, Yongfang Wang, Jinnan Cheng, Philipp Haas, Mahyar Aghapour, Linda Krug, Adelheid Hainzl, Meinhard Wlaschek, Pallab Maity, Karin Scharffetter‐Kochanek   +11 more
wiley   +1 more source

Differential Expression of Interleukin-6 (IL-6), Interleukin-10 (IL-10), and Interleukin-1 Beta (IL-1β) in Insulin Resistance and Type 2 Diabetes: A Comparative Study of Messenger RNA (mRNA) and Protein Levels. [PDF]

Iran J Pathol
Gaber HF, Mohsin MI.
europepmc   +1 more source

A Hypoxia‐Responsive Single‐Atom Sonozyme for Targeted Sonocatalytic Therapy in Alleviating Atherosclerotic Plaque

Advanced Science, EarlyView.
A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen, Guotao Yuan, Zhiwen Liu, Zhengyu Cao, Li He, Ruonan Li, Tongsheng Huang, Minglong Zheng, Kexin Wen, Canxia Huang, Shuang Zhu, Pingyu Zhang, Jingfeng Wang, Yuling Zhang, Yue Pan   +14 more
wiley   +1 more source

Interleukin-10 contrasts inflammatory synaptopathy and central neurodegenerative damage in multiple sclerosis. [PDF]

Front Mol Neurosci
Gilio L, Fresegna D, Stampanoni Bassi M, Musella A, De Vito F, Balletta S, Sanna K, Caioli S, Pavone L, Galifi G, Simonelli I, Guadalupi L, Vanni V, Buttari F, Dolcetti E, Bruno A, Azzolini F, Borrelli A, Fantozzi R, Finardi A, Furlan R, Centonze D, Mandolesi G.   +22 more
europepmc   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Interleukin-10 levels in azithromycin-induced cardiac damage and the protective role of combined selenium and vitamin E treatment. [PDF]

Toxicol Rep
Rohym HH, Hemeda MS, Elsayed AM, Farrag MS, Elsayed HA, Ezzat AA, Ibrahim MA, Makloph M.   +7 more
europepmc   +1 more source

tRNA‐Derived Fragment tRF‐22 Promotes Immunosuppression by Inhibiting HnRNPAB Ubiquitination in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
tRF‐22 fosters an immunosuppressive and pro‐oncogenic tumor microenvironment in ESCC by stabilizing hnRNPAB against TRIM25‐mediated ubiquitination and enhancing TGFβ2 expression, which increases PMN‐MDSCs infiltration and suppresses CD8+ T cells. Targeting tRF‐22 or blocking TGFβ signalling improves anti‐PD1 response, offering a promising therapeutic ...
Ling Pan, Xin Qin, Li Gong, Haining Liu, Bo Cheng, Jing Wang, Yajie Hu, Lingxing Zeng, Yiping Wang, Qingxu Song, Yufeng Cheng   +10 more
wiley   +1 more source

Interleukin-6 and Interleukin-10 as a Predictor of Mortality in Elderly with COVID-19.

Ann Afr Med
Rosyid AN, Puspitasari AD, Sensusiati AD, Nugraha J, Amin M.   +4 more
europepmc   +1 more source

Small extracellular vesicles derived from auricular chondrocytes promote secretion of interleukin 10 in bone marrow M1-like macrophages. [PDF]

Regen Ther
Kobatake T, Miyamoto Y, Fujihara Y, Saijo H, Hoshi K, Hikita A.   +5 more
europepmc   +1 more source