Results 31 to 40 of about 12,361,983 (303)

Macrophage dysfunction initiates colitis during weaning of infant mice lacking the interleukin-10 receptor

eLife, 2017
Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signaling
Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz   +16 more
doaj   +1 more source

Blood concentrations of endothelin, interleukins 6 and 10 in men with diabetes mellitus

Mìžnarodnij Endokrinologìčnij Žurnal, 2021
Background. Pathological activation of cytokines is one of the key links in the pathogenesis of diabetes mellitus (DM) and the development of its complications, in particular from the cardiovascular system.
E.V. Luchytskiy, V.E. Luchytskiy, G.A. Zubkova, V.M. Rybalchenko, I.I. Skladanna   +4 more
doaj   +1 more source

Interleukin-10 inhibits interleukin-1β production and inflammasome activation of microglia in epileptic seizures

Journal of Neuroinflammation, 2019
Microglia are important for secreting chemical mediators of inflammatory responses in the central nervous system. Interleukin (IL)-10 and IL-1β secreted by glial cells support neuronal functions, but the related mechanisms remain vague.
Yi Sun, Jiangjun Ma, Dongfang Li, Pinggan Li, Xiaolin Zhou, Yu Li, Zhan-wen He, Lijun Qin, L. Liang, Xiangyang Luo   +9 more
semanticscholar   +1 more source

The Interleukin-10 Family of Cytokines and Their Role in the CNS

Frontiers in Cellular Neuroscience, 2018
Resident cells of the central nervous system (CNS) play an important role in detecting insults and initiating protective or sometimes detrimental host immunity. At peripheral sites, immune responses follow a biphasic course with the rapid, but transient,
Amanda R Burmeister, I. Marriott
semanticscholar   +1 more source

Cytokine profiling for Egyptian diabetic patients with nephropathy

Journal of Medicine in Scientific Research, 2022
Background Evidence suggests that poor glycemic control is significantly associated with the development of microvascular complications of diabetes such as nephropathy.
Samar M Samir, Abdel R B. Abdel Gaffar, Ibrahim A Emara, Rania Hassan Mohamed   +3 more
doaj   +1 more source

The Correlation between Interleukin-10 Serum with Bacterial Index in Multidrug Therapy-treated Leprosy Patients

Berkala Ilmu Kesehatan Kulit dan Kelamin (Periodical of Dermatology and Venerology), 2016
Background: Immune respons disturbance oftenly found in leprosy patient, mainly in various T cell subset and cytokine immune system arranger. Interleukin-10 produced by Th 2 cell, Th3 cell, monocyte, dendritic cell, eosinophil, mast cell, and ...
Eva Krishna Sutedja, Jono Hadi Agusni, Hartati Purbo Dharmadji   +2 more
doaj   +1 more source

Role of Interleukin-10 in Acute Brain Injuries

Frontiers in Neurology, 2017
Interleukin-10 (IL-10) is an important anti-inflammatory cytokine expressed in response to brain injury, where it facilitates the resolution of inflammatory cascades, which if prolonged causes secondary brain damage.
Joshua M. Garcia, S. Stillings, Jenna L. Leclerc, Harrison Phillips, Nancy J Edwards, S. Robicsek, Brian L. Hoh, Spiros L. Blackburn, S. Doré   +8 more
semanticscholar   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Investigation of Interleukin-10 Promoter Polymorphisms and Interleukin-10 Levels in Children with Irritable Bowel Syndrome

Gut and Liver, 2013
Background/AimsThe aim of this study was to investigate whether genetic variations at positions -1082, -819, and -592 in the interleukin (IL)-10 promoter affect IL-10 production in children with irritable bowel syndrome (IBS).Methods : Ninety-four ...
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source