Results 41 to 50 of about 1,035,955 (303)

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

β7 Integrin Inhibition Can Increase Intestinal Inflammation by Impairing Homing of CD25hiFoxP3+ Regulatory T Cells. [PDF]

, 2020
Background & aimsIntegrin α4β7 mediates lymphocyte trafficking to the gut and gut-associated lymphoid tissues, a process critical for recruitment of effector lymphocytes from the circulation to the gut mucosa in inflammatory bowel disease (IBD) and ...
Eckmann, Lars, Ginsberg, Mark H, Kuk, Wun, Lopez-Ramirez, Miguel Alejandro, Rivera-Nieves, Jesús, Sun, Hao   +5 more
core   +1 more source

Neutrophil and lymphocyte responses to oral Streptococcus in Adamantiades-Behcet's disease [PDF]

, 2005
Immune reactions against microorganisms play an important pathogenic role in Adamantiades-Behçet’s disease (ABD). We had previously obtained Streptococcus sanguinis (strain BD113-20) isolated from the oral cavity of patients with ABD.
Aoki, Aridogan, Bowden, Celet, Direskeneli, Direskeneli, Doran, Emiko Isogai, Frandsen, Frassanito, Hiroshi Isogai, Hiroshi Ohtsuki, Isogai, Katsantonis, Keiji Oguma, Kenji Yokota, Lehner, Mantas, Martin, Misumi, Raziuddin, Sakane, Sugi-Ikai, Tomomi Kurauchi, Toshihiko Matsuo, Turan, Wanahita, Yokota, Yokota, Yoshihito Fujinami, Zouboulis   +30 more
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Serum IL-6 and IL-10 levels are associated with fatal outcomes in patients with SFTS in China

Journal of Infection in Developing Countries
Introduction: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with a high mortality rate and is a public health concern.
Xiaoyi Liu, Fan Zhang, Jinping Qiao, Wentao He   +3 more
doaj   +1 more source

Factors Associated With In Vitro Interferon-gamma Production in Tuberculosis

Journal of the Formosan Medical Association, 2011
Macrophage activation assisted by interferon-gamma (IFN-γ) is a primary mechanism by which Mycobacterium tuberculosis is killed, but IFN-γ (production is inhibited in tuberculosis (TB) patients. The production of IFN-γ is influenced by many factors, such
Chung-Chieh Yu, Yu-Chih Liu, Chien-Ming Chu, Duen-Yau Chuang, Wen-Chen Wu, Huang-Pin Wu   +5 more
doaj   +1 more source

IL-10/β-Endorphin-Mediated Neuroimmune Modulation on Microglia during Antinociception

Brain Sciences, 2023
Microglia are glial cells centrally related to pathophysiology and neuroimmunological regulation of pain through microglia–neuron crosstalk mechanisms. In contrast, anti-inflammatory mechanisms guided by immunological effectors such as IL-10 trigger the ...
Thiago Caetano Andrade Belo, Gabriela Xavier Santos, Bruno Eduardo Gabriel da Silva, Bruno Lopes Gonçalves Rocha, Dennis William Abdala, Larissa Alves Moreira Freire, Fernanda Santos Rocha, Giovane Galdino   +7 more
doaj   +1 more source

Bisdemethoxycurcumin and Its Cyclized Pyrazole Analogue Differentially Disrupt Lipopolysaccharide Signalling in Human Monocyte-Derived Macrophages [PDF]

, 2018
open11noSeveral studies suggest that curcumin and related compounds possess antioxidant and anti-inflammatory properties including modulation of lipopolysaccharide- (LPS-) mediated signalling in macrophage cell models. We here investigated the effects of

core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

THE ASSOCIATION OF PROCALCITONIN, LACTATE, WBC COUNT, AND INTERLEUKIN-10 MAY BE HELPFUL IN THE EARLY DIAGNOSIS OF SEPSIS IN BRAZILIAN PATIENTS

Arquivos de Ciências da Saúde da UNIPAR
Introduction: Sepsis is a set of clinical symptoms resulting from inflammation and infection. Several biomarkers are used for early diagnosis and improved management of sepsis.
Cristiane Alves da Silva Menezes, Victor Hugo Ferreira Gomes, Fernanda Rocha de Freitas, Simone Martins Gonçalves, Pâmela Santos Azevedo, Edna Afonso Reis, Ieda de Fátima Oliveira Silva, Ana Paula Lucas Mota   +7 more
doaj   +1 more source