Results 281 to 290 of about 4,629,468 (340)

Targeting Interleukin-13 Receptor α2 and EphA2 in Aggressive Breast Cancer Subtypes with Special References to Chimeric Antigen Receptor T-Cell Therapy. [PDF]

Int J Mol Sci
Kashyap D, Salman H.
europepmc   +1 more source

Targeted Therapy with a Novel Superantigen-based Fusion Protein Against Interleukin-13 Receptor α2-overexpressing Tumor Cells: An In-silico Study. [PDF]

Iran J Pathol
Gholipour Z, Imani Fooladi AA, Parivar K.   +2 more
europepmc   +1 more source

Interleukin 4, Interleukin 13, and Interleukin 9

Interleukin 4, Interleukin 13, and Interleukin 9
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Interleukin-13 in asthma

Current Opinion in Pulmonary Medicine, 2003
Some time ago, the Th2 cytokine, interleukin (IL)-13, was identified as a critical regulator of the allergic response. Initial studies in animal models of disease provided compelling evidence that IL-13, independent from other Th2 cytokines, was necessary and sufficient to induce all features of allergic asthma.
Marsha, Wills-Karp, Monica, Chiaramonte
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Measurement of Interleukin‐13

Current Protocols in Immunology, 2001
AbstractThis unit describes two protocols that can be used to quantitate interleukin‐13 (IL‐13). The enzyme‐linked immunosorbent assay (ELISA) has the advantage of being highly specific for human IL‐13 and does not recognize other cytokines present in the sample.
Angus, Lauder, Andrew N J, McKenzie
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Interleukin-13: A promising therapeutic target for autoimmune disease.

Cytokine & growth factor reviews, 2019
Interleukin-13 (IL-13) was previously thought to be a redundant presence of IL-4, but in recent years its role in immunity, inflammation, fibrosis, and allergic diseases has become increasingly prominent.
Y. Mao, Chan-Na Zhao, J. Leng, Ruixue Leng, D. Ye, S. Zheng, Hai-Feng Pan   +6 more
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Interleukin-4 and interleukin-13 as possible therapeutic targets in systemic sclerosis.

Cytokine, 2019
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of skin and internal organs. Its pathogenesis, which is still poorly understood, features three main pathogenic moments: an initial diffuse vasculopathy followed by low-grade ...
G. Gasparini, E. Cozzani, A. Parodi
semanticscholar   +1 more source

The role of interleukin-13 in chronic inflammatory intestinal disorders.

Autoimmunity Reviews, 2019
Interleukin (IL)-13 is a cytokine playing a pivotal role in T helper (Th)2 immune response supposed to be implicated in some intestinal disorders. IL-13 is produced by Th2 cells, natural killer T cell, innate lymphoid cells and innate immune cells, which
P. Giuffrida, F. Caprioli, F. Facciotti, A. Di Sabatino   +3 more
semanticscholar   +1 more source

[Interleukin 13 and interleukin 13 receptor involvement in systemic sclerosis].

La Revue de medecine interne, 2007
Interleukin 13 is an immunoregulatory cytokine predominantly secreted by activated Th2 cells. It has similar functions with interleukin 4 and they share a common receptor. However, unlike interleukin 4, l'interleukin 13 does not appear to be important in the initial differentiation of CD4 T into Th2-type cells, but rather appears to be necessary in the
Granel, B., Chevillard, C., Dessein, A.
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Interleukin-4 and Interleukin-13 Signaling Connections Maps

Science, 2003
Cytokines are inflammatory mediators important in responding to pathogens and other foreign challenges. Interleukin-4 (IL-4) and IL-13 are two cytokines produced by T helper type 2 cells, mast cells, and basophils. In addition to their physiological roles, these cytokines are also implicated in pathological conditions such as asthma and allergy.
Ann E, Kelly-Welch, Erica M, Hanson, Mark R, Boothby, Achsah D, Keegan   +3 more
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