Results 151 to 160 of about 63,752,558 (296)

Alternating Shear Force of Respiration Regulates Cell Interactions of Fibroblasts and Macrophages to Promote Soft Tissue Integration of Chest Wall Polyetheretherketone Implants

open access: yesAdvanced Science, EarlyView.
Given that PEEK chest wall implants induce shear force at the soft tissue‐implant interface due to respiratory motion in the early in vivo post‐implantation stage. We confirmed that this mechanical stimulus triggers the PIEZO1/ITGB1/YAP1 signalling axis in L929 and the STAT6/p‐STAT6 pathway in RAW264.7, which in turn mediates adhesion and migration of ...
Rou Huang   +14 more
wiley   +1 more source

Real-World Dose Adjustment and Switching of Interleukin-17/23 Inhibitors for Thai Psoriasis. [PDF]

open access: yesDermatol Res Pract
Chaiyabutr C   +6 more
europepmc   +1 more source

An Avalanche Effect Nanomodulator Triggers Cascade Ferroptosis/Cuproptosis for Immunosuppressive Microenvironment Remodeling

open access: yesAdvanced Science, EarlyView.
A nanomodulator called L‐Arginine/lificiguat@Copper‐hollow Prussian blue@Calcium phosphate nanoparticles is constructed to launch a self‐amplifying “avalanche effect” in tumor cells. The ensuing cascade, triggered by the acidic tumor microenvironment and near‐infrared light, induces calcium overload, generates a reactive oxygen species and reactive ...
Hongmei Zhou   +9 more
wiley   +1 more source

Circulating Interleukin-17 Across Airway Disease Phenotypes: A Single-Center Observational Study. [PDF]

open access: yesJ Clin Med
Porr C   +6 more
europepmc   +1 more source

Versatile Co‐Engineering of Immunogenic Cell Death‐Primed Dead Tumor Cell Bodies With Tumor‐Activated MnO2 for cGAS‐STING‐Potentiated Personalized Immunotherapy

open access: yesAdvanced Science, EarlyView.
DTBEI@CS@MnO2, fabricated via modular electrostatic co‐engineering and photothermal/photodynamic immunogenic cell death, specifically responds to the acidic and GSH‐rich tumor microenvironment. This triggers the release of DTBEI that provides tumor antigens, DNA, and DAMPs, as well as the generation of Mn2+, thereby synergistically potentiating cGAS ...
Bolun Xu   +6 more
wiley   +1 more source

Human colon carcinogenesis is associated with increased interleukin-17-driven inflammatory responses

open access: yes, 2015
Zhaohui Xie,1 Yine Qu,2 Yanli Leng,2 Wenxiu Sun,2 Siqi Ma,2 Jingbo Wei,2 Jiangong Hu,3 Xiaolan Zhang1 1Department of Gastroenterology, Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, People’s Republic of China; 2Department of ...
Ma S   +7 more
core  

Chemical Bond‐Orchestrated Energy Depletion to Augment Lung Cancer Chemo‐Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study grafted dichloroacetic acid (DCA) into perylenediimide (PDI) skeleton via ionic or covalent bond to create novel metabolic agent PDIC‐AC and PDIC‐NAC, explicitly elaborated the underlying energy metabolism and therapeutic mechanism, and developed a promising strategy for energy metabolism‐targeting chemo‐immunotherapy by chemical bond ...
Xuejie Zhao   +5 more
wiley   +1 more source

Association of Serum Interleukin-17 Levels With Vitiligo: A Pilot Cross-Sectional Comparative Study. [PDF]

open access: yesCureus
Ahmad T   +9 more
europepmc   +1 more source

Interleukin-6 and depressive symptom severity in response to physical exercise

open access: yes, 2017
Interleukin-6 and depressive symptom severity in response to physical ...
JJ Liu (16089827)   +6 more
core  

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