Results 161 to 170 of about 4,008,604 (402)
IL-17 is associated with disease severity and targetable inflammatory processes in heart failure [PDF]
Aims Heart failure (HF) is recognized as an inflammatory disease in which cytokines play an important role. In animal HF models, interleukin-17A (IL-17) has been linked to deterioration of cardiac function and fibrosis, whereas knock-out of IL-17 showed ...
Baumhove, Lukas +11 more
core +3 more sources
Experimental Dermatology, 2018 Psoriasis is a chronic, immune‐mediated, systemic inflammatory disease that is defined by a characteristic skin reaction produced when elevated levels of inflammatory cytokines such as interleukin (IL)‐17 alter the growth and differentiation of skin ...
J. Krueger, P. Brunner
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background and Objectives Ofatumumab, a fully human anti‐CD20 monoclonal antibody, is effective in reducing relapses and disability progression in patients with multiple sclerosis. This study aimed to examine immune profile changes associated with ofatumumab in a prospective cohort of Chinese patients with relapsing–remitting multiple ...
Shu Yang +9 more
wiley +1 more source
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium [PDF]
, 1999 Martine Chabaud +6 more
openalex +1 more source
Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis. [PDF]
, 2019 How pathogenic cluster of differentiation 4 (CD4) T cells in rheumatoid arthritis (RA) develop remains poorly understood. We used Nur77-a marker of T cell antigen receptor (TCR) signaling-to identify antigen-activated CD4 T cells in the SKG mouse model ...
Ashouri, Judith F +10 more
core
Interleukin-17/Interleukin-21 and Interferon-g producing T cells specific for β2 Glycoprotein I in atherosclerosis inflammation of systemic lupus erythematosus patients with antiphospholipid syndrome [PDF]
, 2019 Systemic lupus erythematosus is frequently associated with antiphospholipid syndrome. Patients with lupus-antiphospholipid syndrome are characterized by recurrent arterial/venous thrombosis, miscarriages, and persistent presence of autoantibodies against
Alnwaisri, Heba +17 more
core +2 more sources
The Interleukin-23/Interleukin-17 Axis Links Adaptive and Innate Immunity in Psoriasis
Frontiers in Immunology, 2018 Research into the pathophysiology of psoriasis has shed light onto many fascinating immunological interactions and underlying genetic constellations. Most prominent among these is the crosstalk between components of the innate and the adaptive immune ...
M. Schön, L. Erpenbeck
semanticscholar +1 more source
The Interleukin‐23 / Interleukin‐17 axis in intestinal inflammation
Journal of Internal Medicine, 2008 Abstract.Although the precise aetiology of inflammatory bowel disease (IBD) remains unclear, recent discoveries have led to an improved understanding of disease pathogenesis. Whilst these findings have underscored the central role of innate and adaptive immune responses in intestinal inflammation, they have also precipitated a paradigm shift in the key
openaire +3 more sources
Arthritis Care &Research, Volume 77, Issue 4, Page 513-521, April 2025.Objective To assess changes in gene expression following tofacitinib treatment and investigate transcription patterns as potential predictors of treatment response in patients with active juvenile idiopathic arthritis (JIA). Methods Whole‐blood samples were collected from patients with JIA at baseline and after 18 weeks of open‐label tofacitinib ...
Esraa Eloseily +7 more
wiley +1 more source
Salivary Levels of Interleukin-17 in Iranian Patients With Systemic Sclerosis
Acta Medica IranicaSystemic sclerosis (SSc) is a rare immune-mediated rheumatic disease in which the skin, muscles, blood vessels, and internal organs are damaged through chronic inflammation.
Ali Tadayon +5 more
doaj +1 more source