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Interleukin-18 and interleukin-18 Binding Protein [PDF]
Frontiers in Immunology, 2013 Interleukin-18 (IL 18) is a member of the IL 1 family of cytokines. Increasing reports have expanded the role of IL 18 in mediating inflammation in animal models of disease using IL 18 deficient mice, neutralization of IL 18 or deficiency in the IL 18 ...
Charles eDinarello +6 more
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The role of interleukin-18 and interleukin-18 binding protein in K/BxN serum transfer-induced arthritis [PDF]
Frontiers in Immunology, 2023 BackgroundInterleukin-18 is a proinflammatory cytokine, the activity of which is regulated by its natural inhibitor, IL-18 binding protein (IL-18BP). Elevated circulating levels of IL-18 have been observed in patients with systemic juvenile idiopathic ...
Sebastien Fauteux-Daniel +17 more
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Proinflammatory cytokines interleukin-18 and interleukin-6 mediate anorexia induction by trichothecene deoxynivalenol and its congeners [PDF]
Frontiers in Veterinary ScienceAs the common foodborne mycotoxins with the highest pollution rate, deoxynivalenol (DON, also named “vomitoxin”) can harm the health of humans and animals by causing anorectic response.
Chuang Zhou +8 more
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Serum interleukin 18 level in kidney diseases and age [PDF]
Urology AnnalsBackground: Interleukin-18 (IL-18), also known as interferon-gamma inducing factor is a protein which in humans is encoded by the IL18 gene, it is a member of the IL 1 family and has a molecular weight of 18 kDa.
Ghada Abd Eltawab Radwan +2 more
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Association of Interleukin-18 gene polymorphism -137G/C with Allergic rhinitis [PDF]
مجله دانشگاه علوم پزشکی گرگان, 2015 Background and Objective: The interleukin-18 (IL-18) gene on chromosome 11 has been suggested as a susceptibility factor for allergies. It is a member of the IL-1 family that was originally described as interferon (IFN-γ)–inducing factor.
Ramazi Sh +5 more
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Interleukin 18 and interleukin 22 as important immune markers in patients with tuberculosis [PDF]
E3S Web of Conferences, 2023 Tuberculosis (TB) is a lung infection caused by the bacterium Mycobacterium tuberculosis (MTB). TB is a leading cause of death globally, accounting for approximately 1.5 million deaths per year.
Kamoona Firas Mohammad Hussein +1 more
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Interleukin 18 in Immune-mediated rheumatic diseases and COVID-19
Научно-практическая ревматология, 2022 Immune-mediated rheumatic diseases (IMRDs), based on the leading mechanisms of pathogenesis, are conditionally classified into autoimmune, autoinflammatory, and «mixed pattern».
E. L. Nasonov, A. S. Avdeeva
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Dental Research Journal, 2020 Background: Regarding the prevalence and importance of periodontal disease and the potential of salivary biomarkers for the early diagnosis of these diseases, this study was conducted to compare salivary concentrations of Interleukin-17 (IL-17) and ...
Surena Vahabi +2 more
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Interleukin‑17A and Interleukin‑18 level in the blood serum of patients with different clinical course of Rosacea [PDF]
Archives of the Balkan Medical Union, 2018 Introduction. Rosacea is a common chronic dermatosis characterized by lesions of open areas of the skin (face) and torpidity to treatment. The objective of our study was to determine and analyze the content of proinflammatory cytokines – interleukin‑17A
Maryna V. STOROZHUK, Olha I. DENYSENKO
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EMBO Molecular Medicine, 2021 The inflammasome is a cytosolic multiprotein complex that plays a crucial role in inflammation and cell death. The sensor proteins in the inflammasome complex detect various microbial and endogenous stimuli, leading to subsequent caspase activation.
Daisuke Watanabe +2 more
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