Results 41 to 50 of about 898,035 (301)

Pro-inflammatory signaling by IL-10 and IL-22: bad habit stirred up by interferons? [PDF]

open access: yes, 2013
Interleukin (IL)-10 and IL-22 are key members of the IL-10 cytokine family that share characteristic properties such as defined structural features, usage of IL-10R2 as one receptor chain, and activation of signal transducer and activator of ...
Mühl, Heiko
core   +2 more sources

High-dose dexamethasone regulates interleukin-18 and interleukin-18 binding protein in idiopathic thrombocytopenic purpura

open access: yesHaematologica, 2009
To evaluate the effects of high-dose dexamethasone (HD-DXM) on the balance of interleukin-18 (IL-18) and its endogenous antagonist IL-18 binding protein (IL-18BP) in ITP patients, IL-18, IL-18BP as well as IFN-γ, IL-4 plasma levels and platelet counts ...
Ning-ning Shan   +6 more
doaj   +1 more source

Interleukin 18 levels in patients with stable coronary artery disease is associated with IL18RAP and IL18R1 gene polymorphism and the risk of myocardial infarction

open access: yesРоссийский кардиологический журнал, 2020
Aim. To determine the relationship between the serum interleukin (IL) 18 level, the carriage of variant alleles IL18, IL18R1, IL18RAP and the risks of myocardial infarction (MI), hypertension, multifocal atherosclerosis in patients with stable coronary ...
A. V. Ponasenko   +3 more
doaj   +1 more source

De-novo design of complementary (antisense) peptide mini-receptor inhibitor of interleukin 18 (IL-18).

open access: yes, 2004
Complementary (antisense) peptide mini-receptor inhibitors are complementary peptides designed to be receptor-surrogates that act by binding to selected surface features of biologically important proteins thereby inhibiting protein-cognate receptor ...
Bhakoo, Ashish   +4 more
core   +1 more source

Interleukin-18 in Human Milk [PDF]

open access: yesPediatric Research, 2001
We analyzed IL-18 levels of human milk. Colostrum contained significantly higher levels of IL-18 compared with early milk and mature milk. By stepwise multiple linear regression analysis, preterm delivery and pregnancy complications of mothers significantly correlated with high levels of IL-18 in human milk (p = 0.0007 and 0.0018, respectively).
Y, Takahata   +7 more
openaire   +2 more sources

Factors Associated With In Vitro Interferon-gamma Production in Tuberculosis

open access: yesJournal of the Formosan Medical Association, 2011
Macrophage activation assisted by interferon-gamma (IFN-γ) is a primary mechanism by which Mycobacterium tuberculosis is killed, but IFN-γ (production is inhibited in tuberculosis (TB) patients. The production of IFN-γ is influenced by many factors, such
Chung-Chieh Yu   +5 more
doaj   +1 more source

Interleukin-18 gene promoter polymorphisms and recurrent spontaneous abortion [PDF]

open access: yes
Background: IL-18 is a multifunctional cytokine capable of inducing either Th1 or Th2 polarization depending on the immunologic milieu. IL-18 is detected at the materno-fetal interface very soon in early pregnancy.
امانی, داور   +5 more
core   +1 more source

The circulating level of interleukins 6 and 18 in ischemic and idiopathic dilated cardiomyopathy [PDF]

open access: yesJournal of Cardiovascular and Thoracic Research, 2019
Introduction: By aging population, the heart failure and its life-threatening complications have become an enormous issue in public health. Regarding the inflammation as a major contributing pathological factor, the determination of most important ...
Mahdiyar Iravani Saadi   +6 more
doaj   +1 more source

Role of IL-33 in inflammation and disease [PDF]

open access: yes, 2011
Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is expressed by mainly stromal cells, such as epithelial and endothelial cells, and its expression is upregulated following pro-inflammatory stimulation.
Miller, Ashley M.
core   +3 more sources

Interleukin-18 and its gene single nucleotide polymorphisms (SNPs) influence chronic hepatitis C progression

open access: yesJournal of Infection in Developing Countries, 2018
Introduction: Interleukin-18 (IL-18) is a pro-inflammatory cytokine that is induced by hepatitis C virus (HCV) infection. Inter-individual variations of IL-18 gene expression may alter HCV-associated liver injury.
Ebada M Said   +7 more
doaj   +1 more source

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