Emerging Therapies for Recurrent Pericarditis: Interleukin‐1 inhibitors [PDF]
Recurrent pericarditis (RP) is a complex inflammatory disorder associated with adverse outcomes and poor quality of life. After the first episode of acute pericarditis, a non‐negligible group of patients will fail to achieve complete remission despite ...
Saberio Lo Presti +5 more
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Specific Interleukin-1 Inhibitors, Specific Interleukin-6 Inhibitors, and GM-CSF Blockades for COVID-19 (at the Edge of Sepsis): A Systematic Review [PDF]
Sepsis is a syndrome with high mortality, which seriously threatens human health. During the pandemic of coronavirus disease 2019 (COVID-19), some severe and critically ill COVID-19 patients with multiple organ dysfunction developed characteristics ...
Ying Wang +6 more
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Interleukin-1 Inhibitors and Vaccination Including COVID-19 in Inflammatory Rheumatic Diseases: A Nonsystematic Review [PDF]
Newly emerging variants of coronavirus 2 (SARS-CoV-2) raise concerns about the spread of the disease, and with the rising case numbers, the Coronavirus disease 2019 (COVID-19) remains a challenging medical emergency towards the end of the year 2021 ...
Pamir Atagündüz +2 more
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Interleukin-1 inhibitors for acute gout. [PDF]
Acute gout flares cause significant pain and disability and it is important to provide quick and effective pain relief. Traditional options for managing acute flares include colchicine, non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids.To assess the benefits and harms of interleukin-1 inhibitors (anakinra, canakinumab, rilonacept) in ...
Sivera F +4 more
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Is It Time to Revisit the Role of Interleukin-1 Inhibitors in Osteoarthritis? [PDF]
Martin Brom,1 Franziska Saxer,1,2 Linda Mindeholm,1 Matthias Schieker,1 Philip G Conaghan3 1Translational Medicine, Novartis Biomedical Research, Basel, Switzerland; 2Medical Faculty, University of Basel, Basel, Switzerland; 3Leeds Institute of Rheumatic
Brom M +4 more
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Interleukin 1 inhibitors in monogenic autoinflammatory diseases – one size does not fit all [PDF]
Ewa Więsik-Szewczyk
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International multi-centre study of pregnancy outcomes with interleukin-1 inhibitors. [PDF]
To provide outcome data concerning pregnancies exposed to the Interleukin-1 (IL-1) inhibitors prior to conception in both men and women, during pregnancy and breast feeding.Retrospective data were collected from members of the International Society for Systemic Autoinflammatory diseases and collated in a single centre.
Youngstein T +18 more
europepmc +5 more sources
Alopecia Areata and Atopic Dermatitis: Common Mechanisms and Emerging Therapeutics [PDF]
Alice Tang,1 Grace Rachko,2 Flavia Manzo Margiotta,1,3,4 Jasmine Levine,1 Ester Del Duca,1,5 Benjamin Ungar1 1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Rutgers New Jersey Medical School, Newark, NJ, USA ...
Tang A +5 more
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Autoinflammatory diseases (AIDs) are a heterogeneous group of rare genetically determined conditions, the main manifestations of which are episodes of fever in combination with other signs of systemic inflammation: skin rashes, musculoskeletal and ...
S. O. Salugina, E. S. Fedorov
doaj +1 more source
Introduction This study aimed to retrospectively examine the drug survival of tumor necrosis factor (TNF)-alpha inhibitors and switched subsequent biologic agents after discontinuation of TNF inhibitors.
Megumi Kishimoto +6 more
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