Results 1 to 10 of about 387,985 (305)

Emerging Therapies for Recurrent Pericarditis: Interleukin‐1 inhibitors [PDF]

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Recurrent pericarditis (RP) is a complex inflammatory disorder associated with adverse outcomes and poor quality of life. After the first episode of acute pericarditis, a non‐negligible group of patients will fail to achieve complete remission despite ...
Saberio Lo Presti   +5 more
doaj   +5 more sources

Specific Interleukin-1 Inhibitors, Specific Interleukin-6 Inhibitors, and GM-CSF Blockades for COVID-19 (at the Edge of Sepsis): A Systematic Review [PDF]

open access: yesFrontiers in Pharmacology, 2022
Sepsis is a syndrome with high mortality, which seriously threatens human health. During the pandemic of coronavirus disease 2019 (COVID-19), some severe and critically ill COVID-19 patients with multiple organ dysfunction developed characteristics ...
Ying Wang   +6 more
doaj   +2 more sources

Interleukin-1 Inhibitors and Vaccination Including COVID-19 in Inflammatory Rheumatic Diseases: A Nonsystematic Review [PDF]

open access: yesFrontiers in Immunology, 2022
Newly emerging variants of coronavirus 2 (SARS-CoV-2) raise concerns about the spread of the disease, and with the rising case numbers, the Coronavirus disease 2019 (COVID-19) remains a challenging medical emergency towards the end of the year 2021 ...
Pamir Atagündüz   +2 more
doaj   +2 more sources

Interleukin-1 inhibitors for acute gout. [PDF]

open access: yesCochrane Database Syst Rev, 2014
Acute gout flares cause significant pain and disability and it is important to provide quick and effective pain relief. Traditional options for managing acute flares include colchicine, non-steroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids.To assess the benefits and harms of interleukin-1 inhibitors (anakinra, canakinumab, rilonacept) in ...
Sivera F   +4 more
europepmc   +3 more sources

Is It Time to Revisit the Role of Interleukin-1 Inhibitors in Osteoarthritis? [PDF]

open access: yesDiabetes, Metabolic Syndrome and Obesity
Martin Brom,1 Franziska Saxer,1,2 Linda Mindeholm,1 Matthias Schieker,1 Philip G Conaghan3 1Translational Medicine, Novartis Biomedical Research, Basel, Switzerland; 2Medical Faculty, University of Basel, Basel, Switzerland; 3Leeds Institute of Rheumatic
Brom M   +4 more
doaj   +2 more sources

International multi-centre study of pregnancy outcomes with interleukin-1 inhibitors. [PDF]

open access: yesRheumatology (Oxford), 2017
To provide outcome data concerning pregnancies exposed to the Interleukin-1 (IL-1) inhibitors prior to conception in both men and women, during pregnancy and breast feeding.Retrospective data were collected from members of the International Society for Systemic Autoinflammatory diseases and collated in a single centre.
Youngstein T   +18 more
europepmc   +5 more sources

Alopecia Areata and Atopic Dermatitis: Common Mechanisms and Emerging Therapeutics [PDF]

open access: yesJournal of Inflammation Research
Alice Tang,1 Grace Rachko,2 Flavia Manzo Margiotta,1,3,4 Jasmine Levine,1 Ester Del Duca,1,5 Benjamin Ungar1 1Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 2Rutgers New Jersey Medical School, Newark, NJ, USA ...
Tang A   +5 more
doaj   +2 more sources

Biologic disease-modifying antirheumatic drugs in the treatment of major monogenic autoinflammatory diseases: literature review and clinical observation

open access: yesСовременная ревматология, 2021
Autoinflammatory diseases (AIDs) are a heterogeneous group of rare genetically determined conditions, the main manifestations of which are episodes of fever in combination with other signs of systemic inflammation: skin rashes, musculoskeletal and ...
S. O. Salugina, E. S. Fedorov
doaj   +1 more source

Drug Survival of Tumor Necrosis Factor-Alpha Inhibitors and Switched Subsequent Biologic Agents in Patients with Psoriasis: A Retrospective Study

open access: yesDermatology and Therapy, 2023
Introduction This study aimed to retrospectively examine the drug survival of tumor necrosis factor (TNF)-alpha inhibitors and switched subsequent biologic agents after discontinuation of TNF inhibitors.
Megumi Kishimoto   +6 more
doaj   +1 more source

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