Results 101 to 110 of about 167,621 (254)

IL-1 regulates the IL-23 response to wheat gliadin, the etiologic agent of Celiac Disease [PDF]

, 2008
Celiac disease (CD) is an autoimmune disease prevalent in ~1% of the general population. CD is unique because both the major genetic (Human Leukocyte Antigen-DQ2/DQ8 alleles) and etiologic factors (dietary glutens) for susceptibility are known.
Alessio Fasano, Dean L. Mann, Kristina M. Harris   +2 more
core   +1 more source

Preliminary results of safety and efficacy of the interleukin 1 receptor antagonist anakinra in patients with severe lupus arthritis [PDF]

, 2004
B. Ostendorf, C Iking-Konert, K Kurz, G Jung, O Sander, M Schneider   +5 more
openalex   +1 more source

Interleukin-1-receptor antagonist in the Muckle-Wells syndrome [PDF]

, 2003
Hawkins, PN, Lachmann, HJ, McDermott, MF
core   +1 more source

Interleukin-1 Receptor Antagonist (IL-1RN) Gene Variable Number Tandem Repeats (VNTR) Polymorphism Association in men Infertility in Erbil City /Kurdistan Iraq

, 2021
Yassin Kareem Amin, Ashti Mohammad Amin Said, Ahmed A. Al-Naqshbandi, Saeed Ghulam   +3 more
openalex   +2 more sources

Mature tau pathology is not improved by interfering with interleukin-1 receptor signaling in two mouse models of tauopathy.

PLoS ONE
Prior work suggests that the cytokine interleukin-1β (IL-1β) may be a key regulator of tau pathology in the presence of amyloidosis. Here, we tested the possible benefits of interleukin-1 receptor antagonist (IL-1RA) gene therapy in two mouse models of ...
Dylan J Finneran, Brianna M Jackman, Taylor Desjarlais, Alayna Henry, Ahlam S Soliman, Patricia C Muskus, Rama Shankar, Bin Chen, Kevin R Nash, Dave Morgan, Marcia N Gordon   +10 more
doaj   +1 more source

Imbalance Between Interleukin-1β and Interleukin-1 Receptor Antagonist in Epicardial Adipose Tissue Is Associated With Non ST-Segment Elevation Acute Coronary Syndrome [PDF]

, 2020
Valentina Parisi, Laura Petraglia, Serena Cabaro, Vittoria D’Esposito, Dario Bruzzese, Giusy Ferraro, Andrea Urbani, Fabrizio Vincenzo Grieco, Maddalena Conte, Aurelio Caruso, Maria Grimaldi, Antonio De Bellis, Salvatore Severino, Pasquale Campana, Emanuele Pilato, Giuseppe Comentale, Maddalena Raia, Giulia Scalia, Giuseppe Castaldo, Pietro Formisano, Dario Leosco   +20 more
openalex   +1 more source

Targeted delivery of anti-inflammatory therapy to rheumatoid tissue by fusion proteins containing an IL-4-linked synovial targeting peptide [PDF]

, 2011
We provide first-time evidence that the synovial endothelium-targeting peptide (SyETP) CKSTHDRLC successfully delivers conjugated IL-4 to human rheumatoid synovium transplanted into SCID mice. SyETP, previously isolated by in vivo phage display and shown
Ahuva Nissim, Ciara M. Finucane, Costantino Pitzalis, Danielle DiCara, Michele Bombardieri, Rita Jones, Sarah E. Wythe, Stephen J. Mather, Taher E. I. Taher, Y. K. Stella Man, Yuti Chernajovsky   +10 more
core   +1 more source

Interleukin-1 Receptor Antagonist as Therapy for Traumatic Brain Injury. [PDF]

Neurotherapeutics, 2023
Lindblad C, Rostami E, Helmy A.
europepmc   +1 more source

Recombinant Human Interleukin-1 Receptor Antagonist in Severe Traumatic Brain Injury: A Phase II Randomized Control Trial [PDF]

, 2014
Adel Helmy, Mathew R. Guilfoyle, Keri L.H. Carpenter, John D. Pickard, David Menon, Peter J. Hutchinson   +5 more
openalex   +1 more source

Schizophrenia is a TH2 dominant autoimmune disease possibly against acetylcholine receptors of CNS [PDF]

, 2012
Schizophrenia is a very common psychiatric disorder. However, its etiology and pathogenesis is still unknown. Current theory saying that neurotransmitter imbalance such as serotonin or dopamine only provides limited effectiveness in schizophrenia ...
Wanchung(Wan-Jiung) Hu
core   +1 more source