Results 141 to 150 of about 238,614 (342)

Adipose tissue is a major source of interleukin-1 receptor antagonist: upregulation in obesity and inflammation.

open access: yesDiabetes, 2003
The secreted form of the interleukin-1 receptor antagonist (IL-1Ra) is an acute-phase protein intervening in the counterregulation of inflammatory processes. We previously showed that this cytokine antagonist is upregulated in the serum of obese patients,
C. Juge-Aubry   +9 more
semanticscholar   +1 more source

Partial response to anakinra in life-threatening Henoch-Schönlein purpura: case report

open access: yesPediatric Rheumatology Online Journal, 2011
Henoch-Schönlein purpura is one of the most common forms of systemic vasculitis of childhood. We report the response to anakinra, the interleukin-1 receptor antagonist, in a 9 year old girl without prior medical problems who developed life-threatening ...
Boyer Erynn M   +2 more
doaj   +1 more source

Digitonin‐Loaded Nanoscale Metal–Organic Framework for Mitochondria‐Targeted Radiotherapy‐Radiodynamic Therapy and Disulfidptosis

open access: yesAdvanced Materials, EarlyView.
A mitochondria‐targeted cationic nanoscale metal organic framework shows strong radiotherapy‐radiodynamic therapy effects and selectively releases digitonin in acidic tumor microenvironments to induce disulfidptosis of cancer cells and downregulate immune checkpoints in cancer and T cells, thereby eliciting strong antitumor immunity to effectively ...
Wenyao Zhen   +7 more
wiley   +1 more source

Adjusting Cell‐Surface Interactions Through a Covalent Immobilization of Biomolecules

open access: yesAdvanced Materials Interfaces, EarlyView.
This review presents an overview of current and emerging immobilization techniques coupled with an in‐depth investigation of the underlying mechanisms governing the activity and stability of covalently immobilized biomolecules. The aim of this study is to serve as a guide for the development of long‐lasting biomedical coatings with versatile biological
Sara Shakibania   +2 more
wiley   +1 more source

Surface Functionalized Ti3CNTx MXene for Monitoring Sweat pH with Superhydrophobic Protection

open access: yesAdvanced Materials Interfaces, EarlyView.
The highly sensitive, stable, and superhydrophobic pH sensor is made by functionalizing the Ti3CNTx MXene surface with fluoroalkyl silane grafting. This strategy is expected to push forward the application of MXene in sweat pH sensing in the near future. Abstract Real‐time tracking of metabolites, ions, and biomarkers in sweat using wearable sensors is
Hui Yang   +7 more
wiley   +1 more source

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Spatially Controlled 3‐D Multiplexed Aptamer Patterning in Hydrogels

open access: yesAdvanced Materials Interfaces, EarlyView.
A hydrogel platform based on norbornene‐functionalized polyvinyl alcohol enables high‐resolution, 3‐D multiplexed patterning of DNA aptamers via two‐photon polymerization. Two distinct aptamers are covalently immobilized with single micron‐scale precision across the x, y, and z dimensions.
Kevin Roost   +9 more
wiley   +1 more source

Cloning and expression of murine interleukin-1 receptor antagonist in macrophages stimulated by colony-stimulating factor 1 [PDF]

open access: bronze, 1991
H Matsushime   +4 more
openalex   +1 more source

Evolving clinical profile of IL-1β, IL-10 and CTLA-4 gene in rheumatoid factor positive Caucasian population [PDF]

open access: yes, 2011
Rheumatoid arthritis (RA), a systemic autoimmune condition, causes joint damage and sometimes extra-articular lesions (cutaneous vasculitis, neuropathy, Felty’s syndrome, pericarditis, intersticial lung disease) that may be life threatening.
Anupama Sharma, Ajay kumar Singh, Sanjeev kumar Singh, Neelima Singh, Varsha Gupta, Int J Cur Bio Med Sci.
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