Results 191 to 200 of about 238,614 (342)

Muscle Protein Breakdown During Endotoxemia in Rats and After Treatment With Interleukin-1 Receptor Antagonist (IL-1 ra)

, 1992
O Zamir, Per-Olof Hasselgren, William J. O’Brien, Robert C. Thompson, Josef E. Fischer   +4 more
openalex   +2 more sources

Decursin‐Loaded Nanovesicles Target Macrophages Driven by the Pathological Process of Atherosclerosis

Advanced Science, EarlyView.
This study presents decursin, a traditional Chinese medicine monomer, that inhibits lipid accumulation and inflammation in atherosclerosis through PKCδ interaction. A novel targeted delivery system (ALD@EM) is developed to overcome decursin's short half‐life, combining antibody‐mediated targeting, LDL‐facilitated chemotaxis, and enhanced macrophage ...
Hui Chen, Yifeng Zhang, Mirenuer Aikebaier, Yawei Du, Yan Liu, Qing Zha, Lan Zheng, Shuyao Shan, Yanping Wang, Jiawei Chen, Yiping Li, Ke Yang, Ying Yang, Wenguo Cui   +13 more
wiley   +1 more source

Comparison of Peripheral Blood Leukocyte Kinetics After Live Escherichia coli, Endotoxin, or Interleukin-1 α Administration Studies Using a Novel Interleukin-1 Receptor Antagonist

, 1993
A S Hawes, Eva K. Fischer, Michael A. Marano, Kimberly J. Van Zee, Craig S. Rock, Stephen F. Lowry, Steve E. Calvano, Lyle L. Moldawer   +7 more
openalex   +2 more sources

Interleukin-1 Receptor Antagonist Expression in Human Endothelial Cells and Atherosclerosis [PDF]

, 2000
Rachael Dewberry, Hazel M. Holden, David C. Crossman, Sheila E. Francis   +3 more
openalex   +1 more source

Red Blood Cell‐Induced Bacterial Margination Improves Microbial Hemoadsorption on Engineered Cell‐Depleted Thrombi, Restoring Severe Bacteremia in Rats

Advanced Science, EarlyView.
A highly efficient extracorporeal device for treating bacteremia is developed by integrating microfluidic bacterial margination and engineered cell‐depleted thrombi strategically constructed in the device. The rodent models, severely infected with antibiotic‐resistant bacteria, recover from bacteremia after two subsequent extracorporeal blood ...
Bong Hwan Jang, Su Hyun Jung, Seyong Kwon, Sung Jin Park, Joo H. Kang   +4 more
wiley   +1 more source

Arterial Inflammation in Mice Lacking the Interleukin 1 Receptor Antagonist Gene [PDF]

, 2000
Martin J.H. Nicklin, D. E. Hughes, Jenny L. Barton, Jan Ure, Gordon W. Duff   +4 more
openalex   +1 more source

Immunotyping the Tumor Microenvironment Reveals Molecular Heterogeneity for Personalized Immunotherapy in Cancer

Advanced Science, EarlyView.
This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng, Yunfang Yu, Wenjun Qiu, Qiyun Ou, Qianqian Mao, Luyang Jiang, Jianhua Wu, Jiani Wu, Huiyan Luo, Peng Luo, Wenchao Gu, Na Huang, Siting Zheng, Shaowei Li, Yonghong Lai, Xiatong Huang, Yiran Fang, Qiongzhi Zhao, Rui Zhou, Huiying Sun, Wei Zhang, Jianping Bin, Yulin Liao, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Min Shi, Wangjun Liao   +27 more
wiley   +1 more source

Cytokines and Bone Loss in a 5-Year Longitudinal Study—Hormone Replacement Therapy Suppresses Serum Soluble Interleukin-6 Receptor and Increases Interleukin-1-Receptor Antagonist: The Danish Osteoporosis Prevention Study [PDF]

, 2000
Bo Abrahamsen, V. Bonnevie‐Nielsen, E.N. Ebbesen, Jeppe Gram, Henning Beck‐Nielsen   +4 more
openalex   +1 more source

Engineered Tissue Models to Decode Host–Microbiota Interactions

Advanced Science, EarlyView.
Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio, Grace E. Callen, Xuesong He, Bruce J. Paster, Hatice Hasturk, Chiara E. Ghezzi   +5 more
wiley   +1 more source

Radiolabelled interleukin‐1 receptor antagonist for detection of synovitis in patients with rheumatoid arthritis [PDF]

, 2000
Pilar Barrera, Conny J. van der Laken, Otto C. Boerman, Wim J.G. Oyen, Marjo T. P. van de Ven, Peter L. E. M. van Lent, L. B. A. van de Putte, Frans H.M. Corstens   +7 more
openalex   +1 more source