Results 91 to 100 of about 78,083 (294)
Association of inflammatory cytokines with lung function, chronic lung diseases, and COVID-19
iScienceSummary: We investigated the effects of 35 inflammatory cytokines on respiratory outcomes, including COVID-19, asthma (atopic and non-atopic), chronic obstructive pulmonary disease (COPD), and pulmonary function indices, using Mendelian randomization and
Marina O. Rontogianni +21 more
doaj +1 more source
Journal of Neuroinflammation, 2010 Background In the present study, we investigated the roles of P2X7 receptor in recruitment and infiltration of neutrophil during epileptogenesis in rat epilepsy models.
Kang Tae-Cheon +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad +3 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.AngioPlate384 is a 384‐well open‐top platform that automates production of more than 100 miniaturized, perfusable blood vessels embedded in hydrogel and supported by stromal cells. Stromal‐endothelial co‐culture strengthens blood vessel barrier function and yields responses useful for translational planning. Scalable and automation‐ready, it suits drug
Dawn S. Y. Lin +14 more
wiley +1 more source
A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model [PDF]
, 2018 George Thom +10 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.The biomimetic nanoplatform IMNP (ETS1 pDNA/PBAE@ITP‐MM) undergoes targeted disassembly at inflammatory vascular sites to release the ETS1 plasmid (pETS1). This release initiates a cascade of effects that inhibit pathogenic pathways and support immune homeostasis. (Abbreviations: EndMT, endothelial‐to‐mesenchymal transition; EC, endothelial cell; TC, T
Feng Zhang +13 more
wiley +1 more source
Early intervention with Interleukin-1 Receptor Antagonist Protein modulates catabolic microRNA and mRNA expression in cartilage after impact injury [PDF]
, 2015 Amaris A. Genemaras +3 more
openalex +1 more source
Advanced Healthcare Materials, EarlyView.An advanced microneedle patch integrating niobium carbide nanosheets and curcumin is engineered for diabetic wound healing. The system enables dual ROS scavenging and NIR‐enhanced antimicrobial activity, effectively rebalancing the oxidative microenvironment, promoting macrophage repolarization and angiogenesis, and accelerating full‐thickness wound ...
Zhi Zheng +12 more
wiley +1 more source
The effect of tumor necrosis factor binding protein and interleukin-1 receptor antagonist on the development of abdominal aortic aneurysms in a rat model [PDF]
, 1998 Anil Hingorani +6 more
openalex +1 more source