Results 251 to 260 of about 22,989,400 (391)

Cytokine Engineering Approaches for Regenerative Medicine

Advanced Therapeutics, EarlyView.
Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley   +1 more source

Selective activation of interleukin-2/interleukin-15 receptor signaling in tumor microenvironment using paired bispecific antibodies. [PDF]

J Immunother Cancer
Montorfani J, Hatterer E, Chatel L, Lesnier A, Viandier A, Daubeuf B, Nouveau L, Malinge P, Calloud S, Masternak K, Ferlin W, Fischer N, Jandus C, Shang L.   +13 more
europepmc   +1 more source

A phase I clinical trial of recombinant interleukin 2 following high dose chemo-radiotherapy for haematological malignancy: applicability to the elimination of minimal residual disease

, 1989
David Gottlieb, MK Brenner, HE Heslop, ACM Bianchi, C Bello-Fernández, AB Mehta, AC Newland, AR Galazka, EM Scott, A. V. Hoffbrand, H. G. Prentice   +10 more
openalex   +1 more source

An antigen receptor-driven, interleukin 2-independent pathway for proliferation of murine cytolytic T lymphocyte clones. [PDF]

, 1986
R L Moldwin, D W Lancki, Kevan C. Herold, F W Fitch   +3 more
openalex   +1 more source

Loss of NR2F6 Protects from Salmonella Typhimurium Infection

Advanced Science, EarlyView.
Loss of nuclear receptor NR2F6 reduces tissue‐resident macrophage populations. Nr2f6‐deficient mice are protected from weight loss and bacterial load during infection with Salmonella Typhimurium. Pro‐inflammatory cytokines and iron levels are altered in infected Nr2f6‐deficient mice.
Johannes Woelk, Christa Pfeifhofer‐Obermair, Julia Benz, Natascha Brigo, Milena Bamberger, Alexeja Kleiter, Martin Hermann, Guenter Weiss, Natascha Hermann‐Kleiter   +8 more
wiley   +1 more source

Zinc Deficiency Exacerbates Lead-Induced Interleukin-2 Suppression by Regulating CREM Expression. [PDF]

Int J Mol Sci
Trojan HE, Rink L, Jakobs J.
europepmc   +1 more source

Effects of anti-proliferative cyclic AMP on interleukin 2-stimulated gene expression. [PDF]

, 1987
William L. Farrar, Stephen Evans, U R Rapp, John L. Cleveland   +3 more
openalex   +1 more source

Fibronectin Fibers Progressively Lose Their Tension in Invasive Human Breast Carcinoma while Being Tensed in DCIS and Healthy Breast Tissue

Advanced Science, EarlyView.
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville, Charlotte M. Fonta, Cornelia Leo, Lucine Christe, Jörg Goldhahn, Gad Singer, Viola Vogel   +6 more
wiley   +1 more source

Low-dose interleukin-2 induces clonal expansion of BACH2-repressed effector regulatory T cells following acute coronary syndrome. [PDF]

Nat Cardiovasc Res
Case AG, O'Brien JW, Lu Y, Charlier FTW, Zhao X, Weng Y, Masters L, Tuong ZK, Sriranjan R, Cheriyan J, Kemper C, Clatworthy MR, Mallat Z, Zhao TX.   +13 more
europepmc   +1 more source

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment.

Immunity, 1995
D. Willerford, Jianzhu Chen, J. Ferry, L. Davidson, A. Ma, A. Ma, F. Alt, F. Alt   +7 more
semanticscholar   +1 more source