Results 231 to 240 of about 98,375,777 (262)

Reduced serum interleukin-2 associates with higher motor severity and along with CD4 T cell alterations may be an early event in isolated REM Sleep Behaviour Disorder. [PDF]

Brain Behav Immun Health
Afaar F, Youssef P, Hughes L, Chua M, Matar E, Kim WS, Halliday GM, Lewis SJG, Dzamko N.   +8 more
europepmc   +1 more source

Arrayed Magnetic Accelerator Synergistically Enhances Orthodontic Tooth Movement via Microtubule Assembly‐Mediated Periodontal Remodeling

Advanced Science, EarlyView.
Mechanical orthodontic treatment for malocclusion is limited by slow remodeling and risks due to poor biomechanical sensing. This study shows that static magnetic fields (SMFs) enhance mechanical sensation in periodontal ligament cells, promoting inflammation and osteoclast activity.
Yiling Lou, Jiwei Sun, Peng Chen, Caihong Mao, Junyuan Zhang, Haoqi Lei, Xiaoqing Han, Yaxuan Zhang, Yuheng Jiang, Yulin Jia, Bin Su, Lili Chen   +11 more
wiley   +1 more source

The therapeutic potential of interleukin‐2/anti‐interleukin‐2 antibody complex in cold storage‐associated kidney transplantation

Clinical and Translational Discovery
Yao Xia, Jiefu Zhu
doaj   +1 more source

Role of high-dose interleukin-2 for melanoma in the age of cellular therapy. [PDF]

J Immunother Cancer
Buchbinder E, Lotze MT, Margolin KA, Amaria R, Sarnaik A, Seery V, Eroglu Z, Khaddour K, Betof Warner A, Kluger HM, Sznol M, Atkins MB, Mcdermott DF, Silk AW.   +13 more
europepmc   +1 more source

Oral Nanomicelle‐Mediated Sequential Butyrate Production in the Intestine for Ulcerative Colitis and Immunosuppression Treatment

Advanced Science, EarlyView.
After oral administration, inodorous GLU‐BA self‐assembles into nanomicelles in aqueous environments to resist premature gastric adsorption. Upon reaching the intestine, endogenous esterases rapidly cleave the built‐in ester bonds in these nanomicelles to release BA and GLU, with GLU further metabolized by gut microbiota to gradually generate BA ...
Feifei Xin, Zhike Xie, Danyue Zhao, Lin Yang, Yiqun Wan, Zuwei Liu, Situ Xiong, Ying Zhang, Lei Feng, Hao Wan   +9 more
wiley   +1 more source

Enteric ChAT‐Expressing Neurons Mediate the Protective Effect of Lactobacillus plantarum in Inflammatory Bowel Disease

Advanced Science, EarlyView.
In colitis patients and mice, reduced Lactobacillus abundance is observed. Experimental studies show that L. plantarum A736 metabolizes dietary tryptophan into indole‐3‐lactic acid (ILA), while both L. plantarum A736 and ILA impact ChAT‐expressing enteric neurons and acetylcholine levels, thereby regulating intestinal immune responses and alleviating ...
Bing Xia, Yuwei Sun, Jialin Wang, Yike Liu, Lu Wang, Shiqi Jiang, Gaiyan Bai, Ruijing Zhang, Yu Zhang, Rongwei Kou, Danna Wang, Beita Zhao, Junjie Yi, Yu Fu, Xiaoning Liu, Xuebo Liu   +15 more
wiley   +1 more source

First-in-human evaluation of a no-alpha interleukin-2 mutein: safety and preliminary pharmacodynamic and clinical effect. [PDF]

Front Immunol
Caballero Aguirrechu I, Mestre Fernández B, Soriano García JL, Lim Alonso N, Soto García A, Fleites Calvo V, Mariño de la Puente D, Vega Carvajal G, Ávila Pérez JC, Mendoza Hernández I, García López E, Tarinas Reyes A, García-Pérez G, Díaz Borges C, Ledón Naranjo N, Lozada Chang SL, García Vega Y, Alvárez Lobaina A, Alvárez Cardona M, Lorenzo-Luaces Alvárez P, Crombet Ramos T, Carmenate Portilla T, León Monzón K.   +22 more
europepmc   +1 more source

Regulatory function of HSA-miR-186-5p on interleukin-2 expression in lumbar degenerative disc disease: a case-control study and subgroups analysis. [PDF]

Neurosurg Rev
Yaltırık CK, Öndüç GG, Álvarez Noval MK, Etli MU, Sarıkaya C, Bakirezer SD, Yilmaz SG, Şerifoğlu L, Özdoğan S.   +8 more
europepmc   +1 more source

Selectivity of bovine interleukin-2 mutein stimulation on bovine peripheral blood mononuclear cells. [PDF]

J Vet Med Sci
Mitoma S, Uto T, Fukaya T, Tominaga M, Sekiguchi S, Sato K, Norimine J.   +6 more
europepmc   +1 more source

From Scalpel to Syringe: Intralesional Interleukin-2-Based Therapy is Effective for Locally Advanced Periocular Cutaneous Squamous Cell Carcinoma. [PDF]

Ophthalmol Ther
Seddigh S, Lee F, Vidovic D, Gruchy JR, Giacomantonio C, Hussain A.   +5 more
europepmc   +1 more source