A qualitative analysis of a A$β$-monomer model with inflammation processes for Alzheimer's disease [PDF]
We introduce and study a new model for the progression of Alzheimer's disease incorporating the interactions of A$\beta$-monomers, oligomers, microglial cells and interleukins with neurons through different mechanisms such as protein polymerization, inflammation processes and neural stress reactions.
arxiv
A new assay for interleukin-1 in the presence of interleukin-2 [PDF]
A simple and reliable assay for interleukin-1 (IL-1) is described which has the advantage over other assays that it is independent of interleukin-2 (IL-2) production by the test cells. The assay makes possible the detection of IL-1 in the supernatants of T cell populations. The ability of IL-1 to induce IL-2 receptor expression in the absence of T cell
Falk, Werner+2 more
openaire +3 more sources
Activation in lectin-free interleukin 2 (IL-2) containing supernatants of peripheral blood mononuclear leukocytes (PBL) from cancer patients or normal individuals resulted in expression of cytotoxicity toward 20 of 21 natural killer (NK)-resistant fresh ...
E. Grimm+3 more
semanticscholar +1 more source
Placental-mediated increased cytokine response to lipopolysaccharides: a potential mechanism for enhanced inflammation susceptibility of the preterm fetus. [PDF]
BackgroundCerebral palsy is a nonprogressive motor impairment syndrome that has no effective cure. The etiology of most cases of cerebral palsy remains unknown; however, recent epidemiologic data have demonstrated an association between fetal neurologic ...
Belkacemi, Louiza+4 more
core +1 more source
A Fast Second-Order Explicit Predictor-Corrector Numerical Technique To Investigating And Predicting The Dynamic Of Cytokine Levels And Human Immune Cells Activation In Response To Gram-Positive Bacteria: Staphylococcus Aureus [PDF]
This paper develops a second-order explicit predictor-corrector numerical approach for solving a mathematical model on the dynamic of cytokine expressions and human immune cell activation in response to the bacterium staphylococcus aureus (S. aureus). The proposed algorithm is at least zero-stable and second-order accurate.
arxiv
Spontaneous Expression of Interleukin-2 In Vivo in Specific Tissues of Young Mice [PDF]
In situ hybridization and immunohistochemistry were used to determine the spectrum of tissues in which interleukin-2 (IL-2) mRNA and protein are found in healthy, normal young mice.
Rothenberg, Ellen V.+1 more
core +4 more sources
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Recovery of T‐cell function in healthy dogs following cessation of oral cyclosporine administration
Cyclosporine is a potent immunosuppressive agent used to treat immune‐mediated disorders in dogs. Secondary infections sometimes necessitate withdrawal of cyclosporine, but it is not known how long it takes for the immune system to recover after ...
Lakshmi Narayanan+8 more
doaj +1 more source
Background: The cytokine storm and specific biochemical results were both observed during Coronavirus disease 2019 (COVID-19) infection. The aim of this study was to see if there was any correlation between biochemical findings and cytokine levels ...
Ismael Raheem Al-Muhana+3 more
doaj +1 more source
Influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training on the plasma cytokine response to maximum sustainable voluntary ventilation [PDF]
The influence of oxidative stress, diaphragm fatigue, and inspiratory muscle training (IMT) on the cytokine response to maximum sustainable voluntary ventilation (MSVV) is unknown.
Brown PI+10 more
core +1 more source