Results 61 to 70 of about 22,989,400 (391)

Expression of interleukin 2 receptors on activated human B cells. [PDF]

open access: yes, 1984
Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF   +8 more
core  

Role of IL-33 in inflammation and disease [PDF]

open access: yes, 2011
Interleukin (IL)-33 is a new member of the IL-1 superfamily of cytokines that is expressed by mainly stromal cells, such as epithelial and endothelial cells, and its expression is upregulated following pro-inflammatory stimulation.
Miller, Ashley M.
core   +3 more sources

RECOMBINANT CYTOKINES IN THE TREATMENT OF PNEUMONIA. CLINICAL EXPERIENCE

open access: yesInterdisciplinary Approaches to Medicine, 2021
Antimicrobial chemotherapy is a keystone of the treatment of pneumonia. Prescription of antibacterial drugs does not always ensure the success of treatment due to the secondary immune deficiency developing in the process of the disease and the rapid ...
O.A. Gizinger   +2 more
doaj   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy

open access: yesMolecular Therapy: Oncolytics, 2017
Adoptive cell therapy holds much promise in the treatment of cancer but results in solid tumors have been modest. The notable exception is tumor-infiltrating lymphocyte (TIL) therapy of melanoma, but this approach only works with high-dose ...
Riikka Havunen   +12 more
doaj   +1 more source

Elevations in Liver Transaminases in COVID-19: (How) Are They Related?

open access: yesFrontiers in Medicine, 2021
Liver involvement in COVID-19 is not yet well-understood, but elevations in liver transaminases have been described to occur in 14–53% of the cases and are more frequently seen in severe disease.
Henrique Pott-Junior   +7 more
doaj   +1 more source

THE CHANGES IN THE LEVEL OF BETA ENDORPHIN, INTERSLEUKIN-2, INTERLEUKIN-4, INTERLEUKIN-6, IMUNOGLOBULIN AND CORTISOL HORMONE ON THE PRACTICES OF SATRIA NUSANTARA [PDF]

open access: yes, 2010
The purpose of this research is to reveal the changes of immunity at breathing exercises. This is an experimental research study. This research used “randomized pretest-posttest control group design.
Sudarko, Rumpis Agus
core  

Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis [PDF]

open access: yes, 2020
Virus-like particle (VLP)-based anti-infective prophylactic vaccination has been established in clinical use. Although validated in proof-of-concept clinical trials in humans, no VLP-based therapeutic vaccination against self-proteins to modulate chronic
Foerster, John, Molęda, Aleksandra
core   +2 more sources

Binding of interleukin 2 to gangliosides [PDF]

open access: yesFEBS Letters, 1984
Exogenous gangliosides inhibit interleukin 2 (IL2)‐dependent growth of a T cell line, AKIL‐1.E8. IL2 activity is retained by columns of ganglioside covalently linked to poly(L‐lysine)‐agarose and is not eluted with ethylene glycol but is completely recovered by elution with 1% SDS. The ability of gangliosides to inhibit IL2 activity is directly related
Patricia B. Ahrens   +4 more
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

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