Results 81 to 90 of about 98,375,777 (262)

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Characterization of Stimulated γδ T Cells: Phenotypic Analysis and Implications for Allogeneic Cellular Immunotherapy

Cells
Due to their anti-tumor activity and non-major histocompatibility complex (MHC) binding T cell receptor, γδ T cells are suitable candidates for allogeneic cellular immunotherapy in cancer.
Anna Bold, Heike Gross, Marco Bardenbacher, Elisabeth Holzmann, Stefan Knop, Martin Wilhelm   +5 more
doaj   +1 more source

ДИНАМИКА И ВЗАИМОСВЯЗИ СЫВОРОТОЧНЫХ КОНЦЕНТРАЦИЙ ИНТЕРЛЕЙКИНА-2, ИНТЕРЛЕЙКИНА-6, ФАКТОРА НЕКРОЗА ОПУХОЛИ АЛЬФА ПРИ ЦИРРОЗАХ ПЕЧЕНИ ВИРУСНОЙ ЭТИОЛОГИИ

, 2020
ELISA was used to assess serum levels of interleukin-2 (IL-2), interleukin-6 (IL-6) and tumor necrosis factor-a (TNF-a) in liver cirr- hosis patients referred to Child-Pugh Classes A, B, and C.
V. V. Zurabov, B. B. Fishman, С. Ш. Бутримова, Б. Б. Фишман, М. Э. Хапман, M. E. Hapman, M. A. Toneyeva, В. В. Зурабов, В. Е. Куликов, V. Ye. Kulikov, М. А. Тонеева, S. Sh. Butrimova   +11 more
core   +1 more source

Interleukin-2 therapy in patients with HIV infection. [PDF]

, 2009
International audienceBACKGROUND: Used in combination with antiretroviral therapy, subcutaneous recombinant interleukin-2 raises CD4+ cell counts more than does antiretroviral therapy alone.
LANE HC, Collins, G., Babiker, A, INSIGHT ESPRIT STUDY GROUP, WENTWORTH D, Lundgren, J D, ROUTY JP, Fox, L., MITSUYASU R, Lévy, Yves, A Babiker (13489939), Mitsuyasu, R., Routy, J P, Tambussi, G, M Fisher (9886829), LUNDGREN JD, TAMBUSSI G, Lane, H C, Fox, L, COLLINS G, Filice, G, LOSSO MH, Routy, J.,, M H Losso (13489954), Losso, M., H., J D Lundgren (13489990), Cooper, D. A., D A Cooper (13490032), CAGLIUSO, MARIA, H C Lane (16165676), Neaton, J. D., Neaton, J. D, Lundgren, J. D., PHILLIPS A, Darbyshire, J, Losso, M. H., Phillips, A., Routy, J., P., BABIKER A, EMERY S, D Wentworth (13490251), Darbyshire, J., Neaton, James, D., Emery, S, Losso, M.,, F Gordin (13489960), R Mitsuyasu (16165679), SILCAAT SCIENTIFIC COMMITTEE, Emery, S., J P Routy (16165682), Lane, H., C., Babilker, A., J Darbyshire (13490209), COOPER DA, DARBYSHIRE J, A Phillips (816918), Collins, G, Losso, M H, Lundgren, J., D., Tambussi, G., MURDACA, GIUSEPPE, Cooper, D., Levy, Y., Gordin, F, Neaton, J D, G Tambussi (13619023), Mitsuyasu, R, Y Lévy (16165673), Wentworth, D., Lundgren, J.,, Lane, H.,, FOX L, Neaton, James,, NEATON JD, GORDIN F, CONTI, VALENTINA, J D Neaton (13490050), Cooper, D A, Lévy, Y, Routy, J. P., Abrams, D, D Abrams (13398651), LÉVY Y, Abrams, Donald, Wentworth, D, Babiker, A., Gordin, F., Lane, H. C., S Emery (7719341), ABRAMS D, Abrams, D., G Collins (13280751), AIUTI, Fernando, Phillips, A, L Fox (13367124)   +94 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Oral administration of Lactiplantibacillus plantarum GKK1 ameliorates atopic dermatitis in a mouse model

Frontiers in Microbiology
Background/objectivesAtopic dermatitis (AD) is a prevalent chronic skin condition, especially in young children, with rising incidence in developed countries. AD causes repeated scratching, and thus affecting quality of life.
Tzu-Chun Lin, Yu-Chieh Wu, You-Shan Tsai, Shih-Wei Lin, Chin-Chu Chen, Chin-Chu Chen, Chin-Chu Chen, Ming-Ju Chen, Ming-Ju Chen, Yen-Po Chen, Yen-Po Chen   +10 more
doaj   +1 more source

Soluble interleukin 2 receptor levels.

, 2019
Soluble interleukin 2 receptor levels.
Jelle R. Miedema (7512251), Willem A. Dik (5871578), Paul L. A. van Daele (6398810), Laura E. M. Eurelings (7512248), P. Martin van Hagen (7329032), Jan A. M. van Laar (3145434), Virgil A. S. H. Dalm (6004133)   +6 more
core   +1 more source

Truncated Chicken Interleukin-1β with Increased Biologic Activity [PDF]

, 2003
Chicken interleukin-1β (ChIL-1β) is synthesized as a precursor molecule that unlike its mammalian counterpart, lacks a typical caspase-1 cleavage site. Therefore, it was unclear if proteolytic cleavage of ChIL-1β can occur and if cleavage might modulate ...
Erno Duda, Zsuzsa Gyorfy, Duda, Erno, Stäheli, Peter, Peter Staeheli, Staeheli, Peter, Annette Ohnemus, Kaspers, Bernd, Gyorfy, Zsuzsa, Ohnemus, Annette, Bernd Kaspers   +10 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Structure-function relationships for the interleukin 2 receptor system

Memorias do Instituto Oswaldo Cruz, 1987
Receptors for interleukin 2 (IL-2) esit in at least three forms which differ in their subunit compositio, their affinity for ligand and their ability to mediate a cellular reponse.
Richard J. Robb
doaj   +1 more source