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Mental disorders are common in the general population; every year about 25% of the total European population is affected by a mental condition. The prevalence of psychiatric disorders might be underestimated.
Gianluca Pandolfo +6 more
doaj +1 more source
Replicating viral vector platform exploits alarmin signals for potent CD8+ T cell-mediated tumour immunotherapy. [PDF]
Viral infections lead to alarmin release and elicit potent cytotoxic effector T lymphocyte (CTL <sup>eff</sup> ) responses. Conversely, the induction of protective tumour-specific CTL <sup>eff</sup> and their recruitment into the
A Hyvarinen +69 more
core +2 more sources
Behavioral Changes in Mice Lacking Interleukin-33 [PDF]
AbstractInterleukin (IL)-33 is a member of the IL-1 family of cytokines. IL-33 is expressed in nuclei and secreted as alarmin upon cellular damage to deliver a danger signal to the surrounding cells. Previous studies showed that IL-33 is expressed in the brain and that it is involved in neuroinflammatory and neurodegenerative processes in both humans ...
Eisuke Dohi +6 more
openaire +2 more sources
Neonatal malnutrition and macrophage in Candida albicans infection [PDF]
Neonatal malnutrition is an important environmental exposure factor that can influence the development and health of all body systems, including the immune system.
N. G. Morais-Coneglian +6 more
doaj +1 more source
The early transcriptomic response to interleukin 1β and interleukin 33 in rat neonatal cardiomyocytes [PDF]
In the heart, inflammatory cytokines including interleukin (IL) 1β are implicated in regulating adaptive and maladaptive changes, whereas IL33 negatively regulates cardiomyocyte hypertrophy and promotes cardioprotection.
Barrett, Oliver P T +4 more
core +1 more source
Cytokines (interleukin-9, IL-17, IL-22, IL-25 and IL-33) and asthma
Asthma is a reversible airway obstruction that is characterized by constriction of airway smooth muscle, hyper secretion of mucus, edema and airway hyper responsiveness (AHR), mucus secretion and thickening of the basement membrane underlying the airway ...
Rahim Farahani +4 more
doaj +1 more source
Objective: To investigate the clinical significance of interleukin-33(IL-33) and soluble ST2 (sST2) in patients with vitiligo. Methods: The serum concentrations of IL-33 and sST2 were determined by enzyme linked immunosorbent assay (ELISA) respectively ...
Li YANG, Dong-qing LU, Han MA
doaj +1 more source
Leukotrienes provide an NFAT-dependent signal that synergizes with IL-33 to activate ILC2s. [PDF]
Group 2 innate lymphoid cells (ILC2s) and type 2 helper T cells (Th2 cells) are the primary source of interleukin 5 (IL-5) and IL-13 during type 2 (allergic) inflammation in the lung.
Austen, K Frank +5 more
core +1 more source
Effects of IL-33 on HaCAT cell line and psoriasis-like lesion in mouse model [PDF]
Objective To investigate the effects of interleukin-33(IL-33)on HaCAT cells and psoriasis-like inflammation induced by imiquimod(IMQ) in mice. Methods Twenty-four hours after HaCAT cells were plated, the cell proliferation and autophagy-related protein ...
DUAN Ya-ju, WANG Wen-qian, HU Hua, FU Dan-dan, SONG Xiang-feng, TIAN Zhong-wei
doaj
IL-31 and IL-33 in rheumatoid arthritis patients
Objective – to investigate clinical and diagnostic significance of IL-31 and IL-33 determination in patients with rheumatoid arthritis (RA).Material and methods. 154 patients with a reliable diagnosis of RA were examined.
N. A. Lapkina +8 more
doaj +1 more source

