Results 101 to 110 of about 417,438 (262)

Targeting Post‐Irradiation Thyroid Dysfunction: Electrospun Scaffolds As A Dual‐Action Approach for Antioxidant and Immune Modulation

Advanced Healthcare Materials, EarlyView.
Radiation‐induced hypothyroidism follows head and neck radiotherapy due to oxidative stress and inflammation. Electrospun polycaprolactone scaffolds containing adenosine have potential to modulate thyroid repair. Scaffolds enhance thyrocyte proliferation, antioxidant enzymes glutathione peroxidase and catalase, reduce senescence and apoptosis markers ...
Maria Heim, Ella‐Louise Handley, Daniel Grant, Lizi M. Hegarty, Elaine Emmerson, Anthony Callanan   +5 more
wiley   +1 more source

Influence of oxidative stress, diaphragm fatigue and inspiratory muscle training on the plasma cytokine response to maximum sustainable voluntary ventilation

, 2014
The influence of oxidative stress, diaphragm fatigue and inspiratory muscle training (IMT) on the cytokine response to maximum sustainable voluntary ventilation (MSVV) is unknown.
Gonzalez, JT, Neil C. Williams (16672905), Mills, Dean E., Martin J. McPhilimey (16672902), Gonzalez, Javier T., Gonzalez, J.T., Neil C. Williams, Sharpe, GR, Sharpe, Graham R., McPhilimey, Martin J., Williams, NC, Graham R. Sharpe (16661214), Sharpe, G.R., Mills, Dean, Gonzalez, Javier, McPhilimey, Martin, McPhilimey, MJ, McPhilimey, M.J., Johnson, Michael A., Yvonne A. Barnett, Dean E. Mills (16661205), Yvonne A. Barnett (16661208), Graham R. Sharpe, Barnett, YA, Martin J. McPhilimey, Mills, DE, Javier T. Gonzalez (8473264), Barnett, Yvonne, Javier T. Gonzalez, Johnson, M.A., Sharpe, Graham, Williams, N.C., Williams, Neil C., Dean E. Mills, Johnson, MA, Mills, D.E., Barnett, Yvonne A., Barnett, Y.A., Michael A. Johnson, Michael A. Johnson (1317849), Williams, Neil   +40 more
core   +1 more source

Higher Circulating Concentration of Interleukin-38 in Patients with Knee Osteoarthritis: Its Association with Disease Severity

, 2021
Evidence showed that chronic inflammatory and immunopathological responses play a pivotal role in the development of osteoarthritis (OA). Interleukin-38 (IL-38) as a novel anti-inflammatory cytokine with influential modulatory properties on both innate ...
Shayan Rezaee, Abdollah Jafarzadeh, Rezaee, S., Khorramdelazad, H., Mitra Abassifard, Hossein Khorramdelazad, Jafarzadeh, A., Abassifard, M.   +7 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Sepsis beim Hund: Interleukin-6 als prognostischer Parameter

, 2007
Wie auch in der Humanmedizin stellen Sepsis und SIRS den behandelnden Arzt in der Veterinärmedizin vor eine große Herausforderung. Eine optimale therapeutische Intervention setzt besonders die Früherkennung dieser Erkrankungen und damit auch die ...
Rau, Stefanie Maria
core  

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Serum level of periostin and interleukin-38 in atopic asthma and their association with eosinophilic airway inflammatory response

Egyptian Journal of Chest Disease and Tuberculosis
Background Bronchial asthma is a prevalent long-term respiratory disorder that impacts the airways. Periostin and interleukin-38 (IL-38) are crucial in the pathogenesis of atopic asthma, serving as important biomarkers of the eosinophilic inflammatory ...
Aya M. Bedawy, Hanaa S. Hamed, Mohamed T. Anwar, Wesam A. Boghdady, Alaa O. Abdel-Kareem   +4 more
doaj   +1 more source

Serum interleukin-38 levels association with insulin resistance, liver injury and lipids in non-alcoholic fatty liver disease

Ain Shams Medical Journal
Background:Non-alcoholic fatty liver disease [NAFLD] is a prevalent metabolic liver disorder characterized by insulin resistance, dyslipidemia, and systemic inflammation. Interleukin-38 [IL-38], .
Mohamed Salama, Eman Barsy, Tarek Youssef, Nourhan ALY   +3 more
doaj   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source

A common variant of the interleukin 6 receptor (IL-6r) gene increases IL-6r and IL-6 levels, without other inflammatory effects.

, 2007
Interleukin-6 (IL-6) is a key inflammatory cytokine, signalling to most tissues by binding to a soluble IL-6 receptor (sIL-6r), making a complex with gp130.
A Murray, Henley, W, Bandinelli, S, S Rafiq, Rafiq, S, Weedon, MN, Guralnik, JM, Hurst, A, A-M Corsi, Ferrucci, L, K Stevens, S Bandinelli, M N Weedon, Corsi, A-M, L Ferrucci, Murray, A, D Melzer, W Henley, T M Frayling, J M Guralnik, A Hurst, Stevens, K, Melzer, D, Frayling, TM   +23 more
core   +1 more source