Results 91 to 100 of about 417,438 (262)

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice [PDF]

, 1996
MRL/MP-lpr/lpr (MRL/lpr) mice develop a spontaneous autoimmune disease. Serum from these mice contained significantly higher concentrations of nitrite/nitrate than serum from age-matched control MRL/MP-+/+ (MRL/+), BALB/c or CBA/6J mice.
Liew, F. W., G J Feng, Stott, D. I., Huang, Fangping, Feng, G.J., D I Stott, Feng, Gui Jie, Huang, F.P., G Lindop, Stott, David Ian, F Y Liew, Liew, F.Y., Lindop, George B M, F P Huang, Lindop, G., Huang, F. P., Liew, Fooyew, Stott, D.I., Feng, Guijie   +18 more
core   +1 more source

PDB - 5FB8: Structure of Interleukin-16 bound to the 14.1 antibody (311K, 38°C, 200 ns) - random seed #2

, 2023
5FB8: Structure of Interleukin-16 bound to the mAb 14.1 (311K, 38°C, 200 ns) - random seed #2.
Stan, Razvan
core   +1 more source

The protective role of muscone in the development of COPD

Frontiers in Immunology
BackgroundMuscone, a key component of musk, exhibits anti-inflammatory properties. However, its therapeutic potential in inflammatory lung diseases, such as chronic obstructive pulmonary disease (COPD), remains largely unexplored.
Tiantian Feng, Xiaolong Guo, Wei Chen, Yanying Zhang, Runjing Dai, Yinfang Zhang, Yongqi Liu, Yiya Liu, Peng Song, Jingchun Fan   +9 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis

, 2012
Idiopathic pulmonary fibrosis (IPF) is a fatal disease that is unresponsive to current therapies and characterized by excessive collagen deposition and subsequent fibrosis.
Bozinovski, S, O'Donoghue, R.J.J., Prêle, C.M., Ernst, M.R., Anderson, GP, Vlahos, R., Knight, DA, McKenzie, B.S., Wang, B, Jarnicki, AG, Prêle, CM, Laurent, GJ, McAnulty, R.J., Thiem, S, Lau, HL, Vlahos, R, Zhu, H.J., Richards, CD, Mutsaers, SE, Ernst, MR, Stumbles, P.A., Laurent, G.J., Knight, D.A., Thiem, S., Jarnicki, A.G., Lau, H.L., O'Donoghue, RJJ, McAnulty, RJ, Stumbles, P, Richards, C.D., Anderson, G.P., McKenzie, BS, Rose-John, S, Mutsaers, S.E., Zhu, HJ, Wang, B., Jones, J., Rose-John, S., Jones, J, Bozinovski, S.   +39 more
core   +1 more source

Blood Biomarkers and Surface‐Enhanced Raman Spectroscopy for Gout: A Comprehensive Review

Advanced Functional Materials, EarlyView.
Schematic illustrating gout disease progression from asymptomatic hyperuricemia to chronic tophaceous disease, highlighting the limitations of conventional imaging and biochemical diagnostics and the potential of engineered SERS platforms for ultrasensitive blood‐based detection of urate‐related biomarkers across disease stages, with the color gradient
Isuri Perera, Chiranjeevi Kanike, Appurva Tiwari, Hongyan Wu, Larry D. Unsworth, Ben Bin Xu, Xuehua Zhang   +6 more
wiley   +1 more source

Evaluation of serum interleukin-38 levels in different radiographic grades of idiopathic knee osteoarthritis

, 2021
The aim of this study was to assess interleukin-1 beta (IL-1 beta), IL-1Ra, IL-36, and IL-38 levels together with hs-CRP levels in patients with different radiographic grades of knee osteoarthritis (OA) in comparison to healthy individuals.
Gem, Mehmet, Duman, Baver Akcan, Çamurcu, Yalkın, Duman, Serda, Erdinç, Levent   +4 more
core   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Differential regulation of interleukin-17 and interferon-y production in inflammatory bowel disease

, 2010
PhDBackground and Aims. Interleukin (IL)-17 is now known to be involved in a number of chronic inflammatory disorders. However, the mechanisms regulating its production in inflammatory bowel disease (IBD) are still unclear. Methods.
Rovedatti, Laura
core  

Function of the Interleukin (IL)-1 family member IL-38 in human keratinocytes

, 2021
Interleukin (IL)-38 is a member of the IL-1 cytokine family, with the highest expression in differentiating keratinocytes and reported anti-inflammatory activity. However, little data are available regarding its biological functions such as inflammation,
Mermoud, Loïc Xavier
core   +1 more source