Granulomatous Diseases Review Heterogeneity in the granulomatous response to mycobacterial infection in patients with defined genetic mutations in the interleukin 12-dependent interferon-gamma production ...
Kumararatne, D.S. +49 more
core +1 more source
The Biology of Interleukin-38 in Health and Disease [PDF]
Radboud University, 06 december ...
openaire
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Sex-dependent susceptibility to Listeria monocytogenes infection is mediated by differential interleukin-10 production [PDF]
It is well documented that sex-dependent factors affect susceptibility to infection, with most mouse models demonstrating higher resistance in females.
Bastian Pasche +29 more
core +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Interleukin-38 levels and haematological alterations in Giardiasis patients: A case-control study
Objective: Giardiasis, caused by the protozoan Giardia lamblia, remains a globally prevalent parasitic infection linked to considerable morbidity, especially in children.
Milad abdulkathem Lahmod +1 more
doaj +1 more source
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel +4 more
wiley +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Vascular endothelial growth factor production and regulation in rodent and human pituitary tumor cells in vitro [PDF]
Angiogenesis, the formation of a new blood supply, is an essential step in tumorigenesis. Although vascular endothelial growth factor (VEGF) is known to be a very potent angiogenic factor in most solid tumors, little is known about its production and ...
Losa, Marco +16 more
core +1 more source
PDB - 5FB8: Structure of Interleukin-16 bound to the mAb 14.1 (311K, 38°C, 200 ns) - random seed #3
5FB8: Structure of Interleukin-16 bound to the mAb 14.1 (311K, 38°C, 200 ns) - random seed #3.
Stan, Razvan
core +1 more source

