Biocatalytic Nanoregulators Restore Joint Redox‐Immune Homeostasis in Rheumatoid Arthritis
Mesenchymal stem cell‐derived extracellular vesicles (EVs) coat ruthenium‐loaded metal‐organic frameworks (Ru@ZrMOF), creating a targeted therapeutic (Ru@ZrMOF/EVs). This platform scavenges ROS, generates oxygen, and polarizes macrophages from M1 to M2, alleviating inflammation, inhibiting pannus, promoting cartilage repair, and downregulating HIF‐1α ...
Xingheng Wang +7 more
wiley +1 more source
Genetic Deficiency of Interleukin-4 and Interleukin-13 Exacerbates Alcohol- and Cigarette Smoke-Associated Chronic Pancreatitis via the Pancreas-Intestine Axis. [PDF]
Wang J +5 more
europepmc +1 more source
Interleukin-4 induces the activation and collagen production of cultured human intrahepatic fibroblasts via the STAT-6 pathway [PDF]
Lynda Aoudjehane +8 more
openalex +1 more source
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao +8 more
wiley +1 more source
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis. [PDF]
Das M +27 more
europepmc +1 more source
Association of interleukin-4 polymorphisms with multiple sclerosis in southeastern Iranian patients
Mohammad Kazemi Arababadi +4 more
openalex +1 more source
Differential effects of age on chicken heterophil functional activation by recombinant chicken interleukin-2 [PDF]
Kaiser, Pete +2 more
core +1 more source
This study identifies Rubicon as a key platelet protein that bidirectionally regulates GPVI and integrin αIIbβ3 signaling. Platelet Rubicon protects against cerebral ischemia‐reperfusion injury by limiting infarction without increasing hemorrhage.
Xiaoyan Chen +11 more
wiley +1 more source
A functional interleukin-4 homolog is encoded in the genome of infectious laryngotracheitis virus: Unveiling a novel virulence factor. [PDF]
Volkening JD +9 more
europepmc +1 more source

