Results 251 to 260 of about 1,051,125 (350)

RETRACTION: Interleukin-4 Activates Androgen Receptor Through CBP/p300. [PDF]

Prostate
europepmc   +1 more source

The E3 ligases Itch and WWP2 regulate autoimmune neuroinflammation by controlling T_H2 to T_H17 cell conversion via interleukin-4-STAT5 axis in mice. [PDF]

Nat Commun
Zhao M, Zhang C, Zhang X, Mu Q, Li Q, Liu YC.   +5 more
europepmc   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

Advanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li, Yanjie Guo, Jianlin Li, Yimeng Li, Leqian Lin, Hoi Kit Matthew Leung, Qingqing Zhang, Kai‐Fai Lee, Ka‐Wang Cheung, Ernest H. Y. Ng, William S. B. Yeung, Philip C. N. Chiu, Cheuk‐Lun Lee   +12 more
wiley   +1 more source

Impact of Newcastle disease virus vaccines and genetic variations on interleukin-4 activation in broiler chicken. [PDF]

Open Vet J
Edan RJ, Jumaa RS.
europepmc   +1 more source

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Interleukin-4 and -13 Gene Expression Profiles in Immune-Related Bullous Pemphigoid Indicate Efficacy of IL-4/IL-13 Inhibitors. [PDF]

Cancers (Basel)
Arnold L, Morak M, Kramer N, Berking C, Schefzyk M, Hassel JC, Ziemer M, French LE, Gutzmer R, Nashan D, Heinzerling L.   +10 more
europepmc   +1 more source

An asymmetrically dimethylarginated nuclear 90 kDa protein (p90aDMA) induced by interleukin (IL)-2, IL-4 or IL-6 in the tumor microenvironment is selectively degraded by autophagy

, 2016
Lei Sun, Wu-Yan Xia, Shaohua Zhao, Ning Liu, Shanshan Liu, Peng Xiu, Linfeng Li, Xuelei Cao, Jianxin Gao   +8 more
openalex   +2 more sources

Single‐Nucleus Multi‐Omics Reveals Hypoxia‐Driven Angiogenic Programs and Their Epigenetic Control in Sinonasal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Single‐nucleus multi‐omics profiling of sinonasal squamous cell carcinoma unveils a hypoxia‐driven angiogenic axis. A specific hypoxic tumor subpopulation orchestrates endothelial tip cell differentiation via epigenetically regulated ADM and VEGFA secretion.
Chaelin You, Jaewoo Park, Jung Yeon Jang, Junho Noh, Jaehyun Lee, Geunho Kwon, Myeong Sang Yu, Yoo‐Sam Chung, Seung‐Jun Lee, Keunsoo Kang, Jihwan Park, Ji Heui Kim, Kyuho Kang   +12 more
wiley   +1 more source

Trem2 acts as a non-classical receptor of interleukin-4 to promote diabetic wound healing. [PDF]

Clin Transl Med
Zhu X, Zhang C, Jiang W, Zeng Z, Zhang K, Du M, Chen J, Wu Q, Liao W, Chen Y, Fang W, Pan W.   +11 more
europepmc   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source