Microglia M2A Polarization as Potential Link between Food Allergy and Autism Spectrum Disorders
Pharmaceuticals, 2017 Atopic diseases are frequently co-morbid with autism spectrum disorders (ASD). Allergic responses are associated with an activation of mast cells, innate lymphoid cells, and Th2 cells.
Hans O. Kalkman, Dominik Feuerbach
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IL-13R alpha 2 reverses the effects of IL-13 and IL-4 on bronchial reactivity and acetylcholine-induced Ca2+ signaling [PDF]
, 2007 Background: The interleukins IL-4 and IL-13 play a key role in the pathophysiology of asthma. The interleukin receptor IL-13R alpha 2 is believed to act as a decoy receptor, but until now, the functional significance of IL-13R alpha 2 remains vague ...
Bergner, Albrecht +5 more
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The Regulatory Effects of Interleukin-4 Receptor Signaling on Neutrophils in Type 2 Immune Responses
Frontiers in Immunology, 2019 Interleukin-4 (IL-4) receptor (IL-4R) signaling plays a pivotal role in type 2 immune responses. Type 2 immunity ensures several host-protective processes such as defense against helminth parasites and wound repair, however, type 2 immune responses also ...
Cecilie Egholm +4 more
doaj +1 more source
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. [PDF]
, 1996 Reversible airway hyperreactivity underlies the pathophysiology of asthma, yet the precise mediators of the response remain unclear. Human studies have correlated aberrant activation of T helper (Th) 2-like effector systems in the airways with disease. A
Corry, DB +6 more
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Virus-Like Particle-Mediated Vaccination against Interleukin-13 May Harbour General Anti-Allergic Potential beyond Atopic Dermatitis [PDF]
, 2020 Virus-like particle (VLP)-based anti-infective prophylactic vaccination has been established in clinical use. Although validated in proof-of-concept clinical trials in humans, no VLP-based therapeutic vaccination against self-proteins to modulate chronic
Foerster, John, Molęda, Aleksandra
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Russian Open Medical JournalObjective — To evaluate the expression of receptors for interleukin-4 (IL-4R), 6 (IL-6R), toll-like receptors 2 (TLR2) and 4 (TLR4) of T helper (Th) cells (CD4+), as well as the content of interleukin-4 (IL-4) and 6 (IL-6) in the blood serum of patients ...
Tatyana I. Vitkina +2 more
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Dupilumab for Chronic Obstructive Pulmonary Disease: A Systematic Review
BiologicsBackground/Objectives: Dupilumab was recently approved to treat eosinophilic phenotypes of chronic obstructive pulmonary disease (COPD). This systematic review aimed to collect and appraise the efficacy and safety of dupilumab to treat patients with COPD.
Julia Young +6 more
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A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood [PDF]
, 2004 Background: The interleukin (IL) 4/IL13 pathway is involved in the regulation of IgE production associated with atopic diseases. Numerous polymorphisms have been identified in the coding region of the IL4 receptor alpha chain (IL4Ra) and previous ...
Carr, David +7 more
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PENGARUH OLAHRAGA PERNAFASAN TERHADAP PERUBAHAN KADAR BETA ENDORPHIN, INTERLEUKIN-2, INTERLEUKIN-4, INTERLEUKIN-6, IMUNOGLOBULIN G, dan HORMON KORTISOL (Sebuah Kajian Imunologi Pada Aktivitas Fisik) [PDF]
, 2007 The purpose of the research to expressing the changing of immunity at breathing exercise. This research represent of experimental. Device used “randomized pretest-posttest control group design. Population is student M A Mu'Alimin Yogyakarta.
Rumpis Agus Sudarko, M. S
core
Association of interleukin 10 rs1800896 polymorphism with susceptibility to breast cancer: a meta-analysis. [PDF]
, 2020 Objective: To evaluate the correlation between interleukin 10 (IL-10) -1082A/G polymorphism (rs1800896) and breast cancers by performing a meta-analysis.
Liu, Ji-Bin +3 more
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