Increased expression of interleukin-6 gene in gastritis and gastric cancer [PDF]
Brazilian Journal of Medical and Biological ResearchHelicobacter pylori (H. pylori) induces an intense inflammatory response, mediated by proinflammatory cytokines, including interleukin (IL)-6 and its membrane receptor (IL-6R), which activates important signaling pathways in the development of gastric ...
M.P. Santos +7 more
doaj +2 more sources
Interleukin-6 Signaling Pathway and Its Role in Kidney Disease: An Update
Frontiers in Immunology, 2017 Interleukin-6 (IL-6) is a pleiotropic cytokine that not only regulates the immune and inflammatory response but also affects hematopoiesis, metabolism, and organ development.
H. Su, Chuntao Lei, Chun Zhang
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela +13 more
wiley +1 more source
Sexually dimorphic production of interleukin‐6 in respiratory disease
Physiological Reports, 2020 Diverging susceptibility and severity in respiratory diseases is prevalent between males and females. Sex hormones have inconclusively been attributed as the cause of these differences, however, strong evidence exists promoting genetic factors leading to
Karosham D. Reddy +9 more
doaj +1 more source
Changes of Interleukins in Patients with Nosocomial Pneumonia Against a Background of Traumatic Brain Injury: Role in the Diagnosis and Monitoring of Disease [PDF]
, 2017 Introduction. Nosocomial pneumonia (NP) is the second leading frequency and mortality among nosocomial infections. NP is a frequent complication of severe traumatic brain injury (TBI).
Ilchenko, A. (Anastasiia)
core +2 more sources
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo +9 more
wiley +1 more source
Interleukin 6 as an energy allocator in muscle tissue
Nature Metabolism, 2022 Timothy M. Kistner +2 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Neuromyelitis Optica Spectrum Disorder (NMOSD) is a chronic autoimmune neuroinflammatory disease, typically characterized by antibodies against aquaporin 4 (AQP4‐IgG) or myelin oligodendrocyte glycoprotein (MOG‐IgG). Simultaneous seropositivity for both antibodies in a single patient is exceedingly rare.
Yeting Luo, Shuhua Xie, Xianghong Liu
wiley +1 more source
The effect of adolescent treadmill mandatory exercise on symptoms of depression and brain inflammatory responses following maternal separation stress in mature male rats [PDF]
فصلنامه ابن سینا, 2017 Background: Early life stressful events have detrimental effects on brain and behavior associated with development of depression. Also immune-inflammatory responses have been reported to contribute in pathophysiology of depression and many studies have ...
F Zolfaghari +2 more
doaj
Carvacrol alleviates the proconvulsive effects of lipopolysaccharide (LPS) and reduces the gene expression of proinflammatory cytokines interleukin-1 and tumor necrosis factor-α [PDF]
Avicenna Journal of PhytomedicineObjective: Carvacrol has anti-inflammatory effects. According to the links between inflammatory processes and seizures, this study was designed to investigate the potential effect of carvacrol in reducing seizure severity and involvement of hippocampal ...
Hesamodin Bagheripoor +2 more
doaj +1 more source