Results 241 to 250 of about 775,018 (304)

Leonurine Ameliorates Doxorubicin‐Induced Cardiotoxicity via STING/NF‐κB/NLRP3 Inflammasome Signaling Pathway

Advanced Science, EarlyView.
ABSTRACT Doxorubicin‐induced cardiomyopathy (DIC) remains a dose‐limiting clinical challenge. This study reveals that cardiac vascular endothelial cells (CVECs) act as initial sensors of doxorubicin cardiotoxicity: circulating doxorubicin activates the cGAS‑STING pathway in CVECs, triggering NLRP3 inflammasome‑mediated pyroptosis and release of ...
Wang Jun, Chen Xiaoyang, Xu Jianglin, Yang Zhi, Tao Meijiao, He Jiale, Zhao Jiangfeng, Hei Xuanding, Xu Xuegong, Wang Wei, Li Chun   +10 more
wiley   +1 more source

Effect of a freeze-thaw cycle on amniotic fluid interleukin-6 concentrations in pregnancies with preterm prelabor rupture of membranes: Implications for the diagnosis of intra-amniotic inflammation. [PDF]

PLoS One
Spacek R, Bubenikova S, Musilova I, Kuzniciusova N, Janochova K, Kostelkova M, Pavlikova L, Holeckova M, Lubusky M, Simetka O, Jacobsson B, Kacerovsky M.   +11 more
europepmc   +1 more source

Electrical‐Stimulation Hydrogel Electronic Skin for Sustainable Hybrid Biomechanical–Electromagnetic Energy Harvesting and Accelerating Wound Healing

Advanced Science, EarlyView.
A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou, Ming‐Han Lu, Wei‐Chen Peng, Wei‐Chun Yang, Pei‐Yi Liu, Yu‐Hsuan Yang, Yi‐Lin Huang, Cheng‐Hung Tsai, Ting‐Yu Yang, Xuan Zhang, Zhi‐Xian Yan, Ying‐Chih Lai, San‐Yuan Chen   +12 more
wiley   +1 more source

Targeting Interleukin-6 as a Novel Strategy to Overcome Eribulin Resistance in Breast Cancer. [PDF]

Cancer Med
Hattori A, Nagahashi M, Komatsu M, Urano S, Kuroiwa M, Matsushita Y, Katagiri T, Shimoda M, Miyoshi Y.   +8 more
europepmc   +1 more source

Epidermal METTL1‐Mediated m7G Modification Drives Psoriatic Inflammation by Stabilizing Bdkrb1 and Orchestrating Neutrophil Recruitment

Advanced Science, EarlyView.
This study unveils an unrecognized pro‐inflammatory epitranscriptomic checkpoint in psoriasis. By installing m7G modifications on the 5′ UTR of Bdkrb1 mRNA, METTL1 enhances receptor stability to orchestrate keratinocyte‐driven neutrophil recruitment via p38 MAPK signaling.
Chang Zhang, Jiayi Lu, Sihao Yan, Yirui Wang, Zhuo Li, Weiwei Chen, Yang Han, Ziyan Zhang, Yafen Yu, Qi Zhen, Liangdan Sun   +10 more
wiley   +1 more source

The value of interleukin-6 in predicting acute appendicitis in children and distinguishing complicated appendicitis: a systematic review and meta-analysis. [PDF]

Front Immunol
Tan L, Bo C.
europepmc   +1 more source

Cadherin-11 integrates Piezo1 and interleukin-6 signaling to promote fibroblast activation.

Biomater Sci
Astrab LR, Caliari SR.
europepmc   +1 more source

Interleukin-6 in Daily Use in the Intensive Care Unit: Does It Change the Patients' Outcome and Antimicrobial Prescription? An Explorative Study. [PDF]

Life (Basel)
Bexten T, Kasabov R, Bushuven S, Kamphausen A, Schneider-Lindner V, Lindner HA.   +5 more
europepmc   +1 more source

Seminal Interleukin-6 as a Biomarker of Inflammation, Oxidative Stress, and Sperm Dysfunction in Infertile Men. [PDF]

Diseases
Koumba L, Kabbour M, Ed-Doumy S, Norredine M, Zarhouti A, Mbaye MM, Ghazi B, Louanjli N, Benkhalifa M, Ait Mhand R, Aniq Filali O.   +10 more
europepmc   +1 more source