Results 241 to 250 of about 1,103,478 (297)

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

Prognostic role of serum interleukin-6 levels in polytrauma patients: a comprehensive narrative review. [PDF]

J Trauma Inj
Madani N, Halayqeh S, Almahariq H, Al-Badawi A, Alomari M, Haddad B.   +5 more
europepmc   +1 more source

Risk Factors and Predictive Value of Interleukin-6 and Lymphocyte Count in Sepsis-Induced Coagulopathy: A Retrospective Study. [PDF]

Clin Appl Thromb Hemost
B S, Yang L.
europepmc   +1 more source

Circulating Interleukin-6 Levels and Timing of Acute Ischemic Stroke Onset. [PDF]

Ann Clin Transl Neurol
Kowalski RG, Ledreux A, Violette JE, Paustian W, Sillau S, Thompson JA, Neumann RT, Ornelas D, Monte AA, Dylla L, Ginde AA, Farcas AM, Coughlan CM, Jones WJ, Grotta JC, Graner MW.   +15 more
europepmc   +1 more source

Increased levels of systemic iron content in adult-onset interleukin-6 knockout mice. [PDF]

Redox Rep
Zhang F, Zhang C, Luo Q, Li J, Qiu X, Qian Z.   +5 more
europepmc   +1 more source

Interleukin-6, CD8⁺ T cells, and Alzheimer's disease: unraveling neuroimmune crosstalk via genetic and mechanistic insights. [PDF]

Front Aging Neurosci
Xu R, Song W, Zhang X.
europepmc   +1 more source

Association of interleukin-6 (IL-6) with suicide attempt.

Ind Psychiatry J
Shah IR, Manzoor S, Hussain A, Majid S, Khan K.   +4 more
europepmc   +1 more source