Results 91 to 100 of about 689,003 (314)

Analysis of Interieukin-8 Gene Promoter function in Human Osteoblast-like Cells : Regulation by Ca^<2+>-signaling and Cyclosporin A [PDF]

, 2002
2002-12We previously reported that an increase in intracellular calcium by calcium ionophore (A23187) and 4p-phorbol-12β- myristate-13α-acetate (PMA) induced the expression of IL-8 mRNA in human osteoblast-like HOS-TE85 cells and this induction was ...
KAMBE, Fukushi, MURAKAMI, Ryuichiro, MITSUYAMA, Hirohito, ISHIGURO, Naoki, SEO, Hisao   +4 more
core   +1 more source

Correlation Between Different Salivary Interleukins and Clinical Periodontal Parameters

Medical Journal of Babylon
Background: Periodontitis is a multifactorial disease that affects tooth-supporting structures which consequently lead to loss of tooth support and tooth loss. Interleukins showed an important role in periodontal destruction.
Sura Dakhil Jassim, Zainab Hadi Kamil, Zeyad Nazar Majeed   +2 more
doaj   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

In vitro and in vivo activity of human interleukin-8 in dogs [PDF]

, 1994
Interleukin-8 (IL-8), a proinflammatory cytokine produced by human monocytes, fibroblasts, and endothelial and epithelial cells, is effective not only on cells and tissues of human beings but also on those of several animal species.
D. Spreng, Zwahlen, R D, Wyder-Walther, M, R. D. Zwahlen, M. Wyder-Walther, Spreng, David   +5 more
core   +1 more source

Histopathological Evidence of Neurodegenerative Pathology in Epilepsy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Epilepsy affects > 50 million people worldwide and is associated with a disproportionate burden of cognitive impairment. Emerging evidence suggests that neurodegenerative proteinopathies, particularly hyperphosphorylated tau (p‐tau) and amyloid‐β (Aβ), may contribute to cognitive dysfunction in people with epilepsy (PWE), even in the absence ...
Syeda Amrah Hashmi, Aleksander Luniewski, Vanessa Smith, Matthew McCord, Jaideep Kapur, Mark Quigg, Catherine Joshua, Ifrah Zawar   +7 more
wiley   +1 more source

Probiotic therapy in the prevention of pouchitis onset: decreased interleukin-1beta, interleukin-8, and interferon-gamma gene expression. [PDF]

, 2005
BACKGROUND: Probiotic therapy has been shown to prevent the onset of pouchitis and to improve the quality of life in ulcerative colitis patients who required ileal pouch anal anastomosis.
RIZZELLO, FERNANDO, MORSELLI, CLAUDIA, Babel N., Volk H.D., CARAMELLI, ELISABETTA, CAMPIERI, MASSIMO, D'ERRICO, ANTONIETTA, GIONCHETTI, PAOLO, Vergopoulos A., FIORENTINO, MICHELANGELO, Lammers K.M.   +10 more
core   +1 more source

Crucial role of IL-6, IL-8, IL-11 and leptin in tumor microenvironment in a group of patients with GEP-NETs- crosstalk between inflammation and cancer

Frontiers in Endocrinology
IntroductionGEP-NETs constitute a heterogeneous group of rare cancers arising in biologically diverse microenvironments, while their cytokine profiles remain insufficiently characterized.ObjectivesThis study assessed IL-6, IL-8, IL-11 and leptin ...
Agata Świętek, Joanna K. Strzelczyk, Dorota Hudy, Zenon P. Czuba, Karolina Snopek-Miśta, Mariusz Kryj, Katarzyna Kuśnierz, Marcin Zeman, Malgorzata Oczko-Wojciechowska, Daria Handkiewicz-Junak, Janusz Strzelczyk   +10 more
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Characterization of a gp130 Signaling Receptor Polymorphism [PDF]

, 2013
We previously reported an association between human herpesvirus 8 (HHV-8) seroprevalence and increased prostate cancer risk among men on the Caribbean island of Tobago.
Kercher, Katherine
core  

Interleukin 8 as a vaso-occlusive marker in Brazilian patients with sickle cell disease

Brazilian Journal of Medical and Biological Research, 2001
Sickle cell disease has a worldwide distribution and is a public health problem in Brazil. Although vaso-occlusive crisis (VOC) is one of the most important clinical features of the disease, there are still several steps of its pathogenesis which are ...
M.S. Gonçalves, I.L. Queiroz, S.A. Cardoso, A. Zanetti, A.C. Strapazoni, E. Adorno, A. Albuquerque, A. Sant'Ana, M.G. dos Reis, A. Barral, M. Barral Netto   +10 more
doaj   +1 more source