Results 241 to 250 of about 689,003 (314)

Nanozyme‐Reinforced miR‐197‐3p Delivery Resets Metabolic and Senescence Pathways to Rejuvenate Osteoarthritic Cartilage

Advanced Science, EarlyView.
ABSTRACT Osteoarthritis (OA) is a progressive and disabling joint disease driven by oxidative stress, chondrocyte senescence and extracellular matrix (ECM) degradation, yet lacks effective disease‐modifying treatments. In this study, we identified miR‐197‐3p as a previously unrecognized, cartilage‐protective miRNA significantly downregulated in both ...
Xuejie Cai, Zehui Lv, Chen Zhang, Xingdong Yang, Ruoying Wang, Yixin Bian, Jiawei Xu, Han Wang, Yingjie Wang, Long Bai, Jiacan Su, Xisheng Weng   +11 more
wiley   +1 more source

The Impact of Amniotic Fluid Interleukin-6, Interleukin-8, and Metalloproteinase-9 on Preterm Labor: A Narrative Review. [PDF]

Biomedicines
Karampitsakos T, Mavrogianni D, Machairiotis N, Potiris A, Panagopoulos P, Stavros S, Antsaklis P, Drakakis P.   +7 more
europepmc   +1 more source

Targeting NSUN2‐Mediated m5C Modification Attenuates Chondrocyte Senescence and NLRP3 Activation in Osteoarthritis

Advanced Science, EarlyView.
NSUN2‐mediated m5C modification cooperates with ALYREF to stabilize and export IP3R3 mRNA, increasing IP3R3 expression and Ca2 + overload in chondrocytes. This signaling promotes mitochondrial dysfunction, NLRP3 inflammasome activation, and senescence, thereby accelerating osteoarthritis progression.
Guping Mao, Wei Li, Zhencan Lin, Zengfa Deng, Ming Li, Zongrui Jiang, Changzhao Li, Dianbo Long, Yan Kang   +8 more
wiley   +1 more source

Interleukin-8/Matrix Metalloproteinase-9 Axis Impairs Wound Healing in Type 2 Diabetes through Neutrophil Extracellular Traps-Fibroblast Crosstalk. [PDF]

Eur J Immunol
Tsilingiris D, Natsi AM, Gavriilidis E, Antoniadou C, Eleftheriadou I, Anastasiou IA, Tentolouris A, Papadimitriou E, Eftalitsidis E, Kolovos P, Tsironidou V, Giatromanolaki A, Koffa M, Tentolouris N, Skendros P, Ritis K.   +15 more
europepmc   +1 more source

Elevations in interleukin-8 levels in individuals with alcohol use disorder and clinical insomnia symptoms. [PDF]

Alcohol Clin Exp Res (Hoboken)
Grodin EN, Baskerville WA, McManus KR, Irwin MR, Ray LA.   +4 more
europepmc   +1 more source

The Diagnostic and Prognostic Role of Interleukin 6 and Interleukin 8 in Childhood Acute Gastroenteritis-A Review of the Literature. [PDF]

Int J Mol Sci
Adumitrăchioaiei H, Săsăran MO, Mărginean CO.   +2 more
europepmc   +1 more source

Expression of interleukin-8 and integrin β3 predicts prognosis of patients with hepatocellular carcinoma after hepatectomy. [PDF]

Medicine (Baltimore)
Zhang J, Yin Y, Tang J, Ma M, Shen H, Zhang Y, Sun F.   +6 more
europepmc   +1 more source

Postoperative evaluation of interleukin-8 and C1q/TNF-related protein-12 in patients undergoing coronary artery bypass graft surgery. [PDF]

Rev Assoc Med Bras (1992)
Sisakht MT, Pourghadamyari H, Dehesh T, Karim ZR, Nazari-Robati M.   +4 more
europepmc   +1 more source

Aqueous Humor Cytokine Profiling Reveals Distinct Roles for Serum Amyloid A, Interleukin-8, and Endothelin-1 in Pseudoexfoliation Syndrome and Glaucoma. [PDF]

Int J Mol Sci
Kadoh Y, Takayanagi Y, Sugihara K, Kaidzu S, Takai Y, Tanito M.   +5 more
europepmc   +1 more source