Results 251 to 260 of about 14,940,727 (341)

Tumor‐Derived Exosomal circAP2B1 Induces M2 Macrophage Polarization by Enhancing Mitochondrial Homeostasis to Promote Esophageal Squamous Cell Carcinoma Progression

Advanced Science, EarlyView.
ESCC‐derived exosomal circAP2B1 promotes tumor progression by reprogramming mitochondrial metabolism via the ESRRA/KPNA1/MFN2 axis to induce M2 polarization of macrophages. ABSTRACT Esophageal squamous cell carcinoma (ESCC) remodels the immunosuppressive tumor microenvironment via exosome‐mediated intercellular communication.
Yiru Wang, Gang Feng, Youyu Wang, Ruihao Liang, Haixia Pan, Kai Lei   +5 more
wiley   +1 more source

Safety and pharmacology of AMY109, a long-acting anti-interleukin-8 antibody, for endometriosis: a double-blind, randomized phase 1 trial. [PDF]

F S Rep
Wang PH, Hsiao SM, Matsuki S, Hanada R, Chen CA, Nishimoto-Kakiuchi A, Sekiya M, Nakai K, Matsushima J, Sawada M.   +9 more
europepmc   +1 more source

Crosstalk Between CTSB+ Glioblastoma Cells and S100A10+ Macrophages: A Self‐Reinforcing Circuit Promotes Immune Evasion and Limits Response to Immunotherapy

Advanced Science, EarlyView.
In glioblastoma, M2‐polarized macrophages secrete IL‐6, which activates STAT3 signaling in tumor cells to upregulate CTSB. Tumor‐derived CTSB binds the C‐terminus of macrophage S100A10, reinforcing M2 polarization and further IL‐6 secretion, thereby establishing a feedforward IL‐6/STAT3/CTSB/S100A10 loop. This cascade drives tumor growth, invasion, and
Hao Zhang, Nan Zhang, Xisong Liang, Jie Wen, Ziyu Dai, Wantao Wu, Shuyu Li, Songshan Feng, Zaoqu Liu, Zhiwei Xia, Peng Luo, Quan Cheng   +11 more
wiley   +1 more source

Comment on: "Postoperative evaluation of interleukin-8 and C1q/TNF-related protein-12 in patients undergoing coronary artery bypass grafting surgery". [PDF]

Rev Assoc Med Bras (1992)
Rahman ÖF, Ayyıldız F.
europepmc   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Retraction Note: Osteogenic differentiation of mesenchymal stem cells promotes c-Jun-dependent secretion of Interleukin 8 and mediates the migration and differentiation of CD4+T cells. [PDF]

Stem Cell Res Ther
Ye F, Li J, Xu P, Xie Z, Zheng G, Liu W, Ye G, Yu W, Lin J, Su Z, Che Y, Zhang Z, Wang P, Wu Y, Shen H.   +14 more
europepmc   +1 more source

USP5 Stabilizes TGFBR1 to Drive Vascular Smooth Muscle Cell Senescence and Atherosclerosis

Advanced Science, EarlyView.
This study reveals that USP5 drives vascular smooth muscle cell senescence and atherosclerosis by stabilizing TGFBR1, suppressing IDH2, and promoting glycolytic reprogramming, identifying the USP5‐TGFBR1‐IDH2 axis as a potential therapeutic target. ABSTRACT Vascular smooth muscle cell (VSMC) senescence contributes importantly to atherosclerotic plaque ...
Xinhai Cui, Yuanlong Hu, Lin Lin, Lei Zhang, Chao Li, Yunlun Li   +5 more
wiley   +1 more source

An auxiliary diagnostic strategy for distinguishing Guillain-Barré syndrome and chronic inflammatory demyelinating polyneuropathy: combining platelet-to-lymphocyte ratio and cerebrospinal fluid interleukin-8 levels. [PDF]

BMC Neurol
Song S, Bai Y, Mu H, Xiao J, Li W, Zhao Y, Yan C, Zheng J, Wang C, Wang Q.   +9 more
europepmc   +1 more source

Effect of interleukin-6 and interleukin-8 levels on pathogenic bacteria types in patients with advanced lung cancer and pulmonary infection during chemotherapy. [PDF]

Am J Transl Res
Zheng X, Lan H, Hu Y, Tian P.
europepmc   +1 more source

Assessing the Usefulness of Interleukin-8 as a Biomarker of Inflammation and Metabolic Dysregulation in Dairy Cows. [PDF]

Int J Mol Sci
Puppel K, Slósarz J, Solarczyk P, Grodkowski G, Kostusiak P, Kalińska A, Balcerak M, Kunowska-Slósarz M, Gołębiewski M.   +8 more
europepmc   +1 more source