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Interleukin-8 and Interleukin-17 for Cancer
Cancer Investigation, 2014Pro-inflammatory cytokines have been associated with chronic inflammation and inflammatory diseases. Increased levels of interleukins (ILs) have been associated with inflammatory disease exacerbation. ILs levels have been observed to be associated with advance stage cancer for several types of cancer and a poor prognostic maker for malignant disease ...
Paul, Zarogoulidis +5 more
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The expression of interleukin-8 and interleukin-8 receptors in endometrial carcinoma
Cytokine, 2012Interleukin-8 (IL-8) is a pro-inflammatory cytokine which exerts its effects via binding to 2 receptors, CXCR1 and CXCR2 and is known to promote angiogenesis, mitogenesis and motogenesis in cancer. IL-8 is over expressed in endometrial carcinoma, but the expression of CXCR1 and CXCR2 in endometrial carcinoma has not been previously investigated.
Lauren, Ewington +5 more
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Interleukin-8: An evolving chemokine
Cytokine, 2022Early in the 1980s several laboratories mistakenly reported that partially purified interleukin-1 (IL-1) was chemotactic for neutrophils. However, further investigations by us, revealed that our purified IL-1 did not have neutrophil chemotactic activity and this activity in the LPS-stimulated human monocyte conditioned media could clearly be separated ...
Kouji, Matsushima +2 more
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Interleukin‐8 in neonatal sepsis
Acta Paediatrica, 2001This study was conducted to evaluate the accuracy and kinetics of interleukin 8 (IL-8) as a test for early-onset bacterial infections (EOBI) in neonates and to examine whether IL-8 would allow unnecessary antibiotic therapy to be reduced. First, IL-8 was measured 378 times on admission, along with C-reactive protein (CRP), immature to total neutrophil ...
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Interleukin-6 and Interleukin-8 in Newborn Bacterial Infection
American Journal of Perinatology, 2001The objective of this study is to determine the plasma concentrations and diagnostic accuracy of interleukin-6 (IL-6) and interleukin-8 (IL-8) in newborn infection. One hundred and one newborn infants with clinical signs of infection during their primary hospitalization were investigated with the minimum of a blood culture, C-reactive protein (CRP ...
Mehr, Sam S. +4 more
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Interleukin 8 in Behçet's Disease
The Journal of Dermatology, 1994AbstractActivated peripheral polymorphonuclear leukocytes (PMNs) and infiltration of PMNs into the lesions are characteristic findings of Behçet's disease (BD). A variety of cytokines, including interleukin 8 (IL‐8), have been shown to activate PMNs. To investigate the role of IL‐8 in the development of BD lesions, IL‐8 production in vivo and in vitro ...
R, Itoh +4 more
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Interleukin 8 in the Human Colostrum
Neonatology, 2002We investigated the postpartum changes in colostral interleukin (IL) 8 concentrations during the first 3 postpartum days and examined the IL-8 production of colostral cells at the levels of both protein and mRNA. Colostrum samples were obtained from healthy mothers after full-term delivery.
Shintaro, Hashira +2 more
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Amniochorion: A Source of Interleukin‐8
American Journal of Reproductive Immunology, 1995PROBLEM: Preterm labor and premature rupture of the membranes are major complications of pregnancy. We have reported the possible role of amniochorionic membrane in the production of inflammatory cytokines and the early onset of labor. This study was conducted to detect the expression of IL‐8 mRNA and peptide production in cultured fetal membranes ...
S J, Fortunato, R, Menon, K F, Swan
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